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Selective Inhibitors of Histone Deacetylases 1 and 2 Synergize with Azacitidine in Acute Myeloid Leukemia.

Min C, Moore N, Shearstone JR, Quayle SN, Huang P, van Duzer JH, Jarpe MB, Jones SS, Yang M.

PLoS One. 2017 Jan 6;12(1):e0169128. doi: 10.1371/journal.pone.0169128. eCollection 2017.


Vitamin C enhances epigenetic modifications induced by 5-azacytidine and cell cycle arrest in the hepatocellular carcinoma cell lines HLE and Huh7.

Sajadian SO, Tripura C, Samani FS, Ruoss M, Dooley S, Baharvand H, Nussler AK.

Clin Epigenetics. 2016 Apr 30;8:46. doi: 10.1186/s13148-016-0213-6. eCollection 2016.


p21 induction plays a dual role in anti-cancer activity of ursolic acid.

Zhang X, Song X, Yin S, Zhao C, Fan L, Hu H.

Exp Biol Med (Maywood). 2016 Mar;241(5):501-8. doi: 10.1177/1535370215616195. Epub 2015 Nov 17.


The protein activator of protein kinase R, PACT/RAX, negatively regulates protein kinase R during mouse anterior pituitary development.

Dickerman BK, White CL, Kessler PM, Sadler AJ, Williams BR, Sen GC.

FEBS J. 2015 Dec;282(24):4766-81. doi: 10.1111/febs.13533. Epub 2015 Oct 26.


A fluorescent bimolecular complementation screen reveals MAF1, RNF7 and SETD3 as PCNA-associated proteins in human cells.

Cooper SE, Hodimont E, Green CM.

Cell Cycle. 2015 Aug 3;14(15):2509-19. doi: 10.1080/15384101.2015.1053667. Epub 2015 Jun 1.


The activity and stability of the intrinsically disordered Cip/Kip protein family are regulated by non-receptor tyrosine kinases.

Huang Y, Yoon MK, Otieno S, Lelli M, Kriwacki RW.

J Mol Biol. 2015 Jan 30;427(2):371-86. doi: 10.1016/j.jmb.2014.11.011. Epub 2014 Nov 20.


Aberrant cell cycle reentry in human and experimental inclusion body myositis and polymyositis.

Kwon B, Kumar P, Lee HK, Zeng L, Walsh K, Fu Q, Barakat A, Querfurth HW.

Hum Mol Genet. 2014 Jul 15;23(14):3681-94. doi: 10.1093/hmg/ddu077. Epub 2014 Feb 20.


Polycomb protein SCML2 regulates the cell cycle by binding and modulating CDK/CYCLIN/p21 complexes.

Lecona E, Rojas LA, Bonasio R, Johnston A, Fernández-Capetillo O, Reinberg D.

PLoS Biol. 2013 Dec;11(12):e1001737. doi: 10.1371/journal.pbio.1001737. Epub 2013 Dec 17.


The tail that wags the dog: p12, the smallest subunit of DNA polymerase δ, is degraded by ubiquitin ligases in response to DNA damage and during cell cycle progression.

Lee MY, Zhang S, Lin SH, Wang X, Darzynkiewicz Z, Zhang Z, Lee EY.

Cell Cycle. 2014;13(1):23-31. doi: 10.4161/cc.27407. Epub 2013 Dec 3.


Recruitment of trimeric proliferating cell nuclear antigen by G1-phase cyclin-dependent kinases following DNA damage with platinum-based antitumour agents.

He G, Kuang J, Koomen J, Kobayashi R, Khokhar AR, Siddik ZH.

Br J Cancer. 2013 Oct 29;109(9):2378-88. doi: 10.1038/bjc.2013.613. Epub 2013 Oct 8.


A novel function of CRL4(Cdt2): regulation of the subunit structure of DNA polymerase δ in response to DNA damage and during the S phase.

Zhang S, Zhao H, Darzynkiewicz Z, Zhou P, Zhang Z, Lee EY, Lee MY.

J Biol Chem. 2013 Oct 11;288(41):29550-61. doi: 10.1074/jbc.M113.490466. Epub 2013 Aug 2.


UV-triggered p21 degradation facilitates damaged-DNA replication and preserves genomic stability.

Mansilla SF, Soria G, Vallerga MB, Habif M, Martínez-López W, Prives C, Gottifredi V.

Nucleic Acids Res. 2013 Aug;41(14):6942-51. doi: 10.1093/nar/gkt475. Epub 2013 May 30.


Quantitative profiling of DNA damage and apoptotic pathways in UV damaged cells using PTMScan Direct.

Stokes MP, Silva JC, Jia X, Lee KA, Polakiewicz RD, Comb MJ.

Int J Mol Sci. 2012 Dec 21;14(1):286-307. doi: 10.3390/ijms14010286.


Aminoimidazole carboxamide ribonucleotide (AICAR) inhibits the growth of retinoblastoma in vivo by decreasing angiogenesis and inducing apoptosis.

Theodoropoulou S, Brodowska K, Kayama M, Morizane Y, Miller JW, Gragoudas ES, Vavvas DG.

PLoS One. 2013;8(1):e52852. doi: 10.1371/journal.pone.0052852. Epub 2013 Jan 3.


Differential activities of the two closely related withanolides, Withaferin A and Withanone: bioinformatics and experimental evidences.

Vaishnavi K, Saxena N, Shah N, Singh R, Manjunath K, Uthayakumar M, Kanaujia SP, Kaul SC, Sekar K, Wadhwa R.

PLoS One. 2012;7(9):e44419. doi: 10.1371/journal.pone.0044419. Epub 2012 Sep 4.


PCNA structure and function: insights from structures of PCNA complexes and post-translationally modified PCNA.

Dieckman LM, Freudenthal BD, Washington MT.

Subcell Biochem. 2012;62:281-99. doi: 10.1007/978-94-007-4572-8_15. Review.


Mouse Rif1 is a key regulator of the replication-timing programme in mammalian cells.

Cornacchia D, Dileep V, Quivy JP, Foti R, Tili F, Santarella-Mellwig R, Antony C, Almouzni G, Gilbert DM, Buonomo SB.

EMBO J. 2012 Sep 12;31(18):3678-90. doi: 10.1038/emboj.2012.214. Epub 2012 Jul 31.


p21CIP1 mediates reciprocal switching between proliferation and invasion during metastasis.

Qian X, Hulit J, Suyama K, Eugenin EA, Belbin TJ, Loudig O, Smirnova T, Zhou ZN, Segall J, Locker J, Phillips GR, Norton L, Hazan RB.

Oncogene. 2013 May 2;32(18):2292-303, 2303.e1-7. doi: 10.1038/onc.2012.249. Epub 2012 Jul 2.


Insights into phosphorylation-dependent mechanisms regulating USP1 protein stability during the cell cycle.

Cotto-Rios XM, Jones MJ, Huang TT.

Cell Cycle. 2011 Dec 1;10(23):4009-16. doi: 10.4161/cc.10.23.18501. Epub 2011 Dec 1. Review.

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