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Items: 1 to 20 of 37

1.

Investigating the Influence of Magnesium Ions on p53-DNA Binding Using Atomic Force Microscopy.

Chen Y, Gao T, Wang Y, Yang G.

Int J Mol Sci. 2017 Jul 21;18(7). pii: E1585. doi: 10.3390/ijms18071585.

2.

Two p53 tetramers bind one consensus DNA response element.

Kearns S, Lurz R, Orlova EV, Okorokov AL.

Nucleic Acids Res. 2016 Jul 27;44(13):6185-99. doi: 10.1093/nar/gkw215. Epub 2016 Mar 31.

3.

A novel radiation-induced p53 mutation is not implicated in radiation resistance via a dominant-negative effect.

Sun Y, Myers CJ, Dicker AP, Lu B.

PLoS One. 2014 Feb 18;9(2):e87492. doi: 10.1371/journal.pone.0087492. eCollection 2014.

4.

Wild-type and mutant p53 mediate cisplatin resistance through interaction and inhibition of active caspase-9.

Chee JL, Saidin S, Lane DP, Leong SM, Noll JE, Neilsen PM, Phua YT, Gabra H, Lim TM.

Cell Cycle. 2013 Jan 15;12(2):278-88. doi: 10.4161/cc.23054. Epub 2012 Jan 15.

5.

Quaternary structure of the specific p53-DNA complex reveals the mechanism of p53 mutant dominance.

Aramayo R, Sherman MB, Brownless K, Lurz R, Okorokov AL, Orlova EV.

Nucleic Acids Res. 2011 Nov 1;39(20):8960-71. doi: 10.1093/nar/gkr386. Epub 2011 Jul 14.

6.

Control of gene expression by modulated self-assembly.

Vilar JM, Saiz L.

Nucleic Acids Res. 2011 Sep 1;39(16):6854-63. doi: 10.1093/nar/gkr272. Epub 2011 May 20.

7.

Single-Molecule characterization of oligomerization kinetics and equilibria of the tumor suppressor p53.

Rajagopalan S, Huang F, Fersht AR.

Nucleic Acids Res. 2011 Mar;39(6):2294-303. doi: 10.1093/nar/gkq800. Epub 2010 Nov 18.

8.

Cooperativity dominates the genomic organization of p53-response elements: a mechanistic view.

Pan Y, Nussinov R.

PLoS Comput Biol. 2009 Jul;5(7):e1000448. doi: 10.1371/journal.pcbi.1000448. Epub 2009 Jul 24.

9.

Zinc coordination is required for and regulates transcription activation by Epstein-Barr nuclear antigen 1.

Aras S, Singh G, Johnston K, Foster T, Aiyar A.

PLoS Pathog. 2009 Jun;5(6):e1000469. doi: 10.1371/journal.ppat.1000469. Epub 2009 Jun 12.

10.

Loss of IKKbeta activity increases p53 stability and p21 expression leading to cell cycle arrest and apoptosis.

Yang PM, Huang WC, Lin YC, Huang WY, Wu HA, Chen WL, Chang YF, Chou CW, Tzeng CC, Chen YL, Chen CC.

J Cell Mol Med. 2010 Mar;14(3):687-98. doi: 10.1111/j.1582-4934.2009.00712.x. Epub 2009 Feb 20.

11.

Noncanonical DNA motifs as transactivation targets by wild type and mutant p53.

Jordan JJ, Menendez D, Inga A, Noureddine M, Bell DA, Resnick MA.

PLoS Genet. 2008 Jun 27;4(6):e1000104. doi: 10.1371/journal.pgen.1000104. Erratum in: PLoS Genet. 2008 Nov;4(11).doi.org/10.1371/annotation/f7fc9c28-14ae-480d-a69e-ee9cc4fba9a7. PLoS Genet. 2008 Jul;4(7). doi: 10.1371/annotation/13bc83be-2345-401d-b953-f1886e9fbdff. Nourredine, Maher [corrected to Noureddine, Maher]; Bell, Douglas [corrected to Bell, Douglas A].

12.

Dimerization of the human papillomavirus type 16 E2 N terminus results in DNA looping within the upstream regulatory region.

Hernandez-Ramon EE, Burns JE, Zhang W, Walker HF, Allen S, Antson AA, Maitland NJ.

J Virol. 2008 May;82(10):4853-61. doi: 10.1128/JVI.02388-07. Epub 2008 Mar 12.

13.

Ab initio thermodynamic modeling of distal multisite transcription regulation.

Saiz L, Vilar JM.

Nucleic Acids Res. 2008 Feb;36(3):726-31. Epub 2007 Dec 1.

14.

Genetic and epigenetic mechanisms of gene regulation during lens development.

Cvekl A, Duncan MK.

Prog Retin Eye Res. 2007 Nov;26(6):555-97. Epub 2007 Jul 28. Review.

15.

Biological consequences of tightly bent DNA: the other life of a macromolecular celebrity.

Garcia HG, Grayson P, Han L, Inamdar M, Kondev J, Nelson PC, Phillips R, Widom J, Wiggins PA.

Biopolymers. 2007 Feb 5;85(2):115-30. Review.

16.

The structure of p53 tumour suppressor protein reveals the basis for its functional plasticity.

Okorokov AL, Sherman MB, Plisson C, Grinkevich V, Sigmundsson K, Selivanova G, Milner J, Orlova EV.

EMBO J. 2006 Nov 1;25(21):5191-200. Epub 2006 Oct 19.

17.

Structural and dynamic basis of a supercoiling-responsive DNA element.

Bae SH, Yun SH, Sun D, Lim HM, Choi BS.

Nucleic Acids Res. 2006 Jan 9;34(1):254-61. Print 2006.

18.

Comparison of the protein-protein interfaces in the p53-DNA crystal structures: towards elucidation of the biological interface.

Ma B, Pan Y, Gunasekaran K, Venkataraghavan RB, Levine AJ, Nussinov R.

Proc Natl Acad Sci U S A. 2005 Mar 15;102(11):3988-93. Epub 2005 Feb 28.

19.

Disruption of protein-mediated DNA looping by tension in the substrate DNA.

Blumberg S, Tkachenko AV, Meiners JC.

Biophys J. 2005 Mar;88(3):1692-701. Epub 2005 Jan 14.

20.

Replication of damaged DNA in vitro is blocked by p53.

Zhou J, Prives C.

Nucleic Acids Res. 2003 Jul 15;31(14):3881-92.

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