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Items: 1 to 20 of 137

1.

Co-targeting of Tiam1/Rac1 and Notch ameliorates chemoresistance against doxorubicin in a biomimetic 3D lymphoma model.

Ikram M, Lim Y, Baek SY, Jin S, Jeong YH, Kwak JY, Yoon S.

Oncotarget. 2017 Dec 8;9(2):2058-2075. doi: 10.18632/oncotarget.23156. eCollection 2018 Jan 5.

2.

RAC1 Missense Mutations in Developmental Disorders with Diverse Phenotypes.

Reijnders MRF, Ansor NM, Kousi M, Yue WW, Tan PL, Clarkson K, Clayton-Smith J, Corning K, Jones JR, Lam WWK, Mancini GMS, Marcelis C, Mohammed S, Pfundt R, Roifman M, Cohn R, Chitayat D; Deciphering Developmental Disorders Study, Millard TH, Katsanis N, Brunner HG, Banka S.

Am J Hum Genet. 2017 Sep 7;101(3):466-477. doi: 10.1016/j.ajhg.2017.08.007.

3.

A CDC42-centered signaling unit is a dominant positive regulator of endothelial integrity.

Amado-Azevedo J, Reinhard NR, van Bezu J, de Menezes RX, van Beusechem VW, van Nieuw Amerongen GP, van Hinsbergh VWM, Hordijk PL.

Sci Rep. 2017 Aug 31;7(1):10132. doi: 10.1038/s41598-017-10392-0.

4.

TIAM1 variants improve clinical outcome in neuroblastoma.

Sanmartín E, Yáñez Y, Fornés-Ferrer V, Zugaza JL, Cañete A, Castel V, Font de Mora J.

Oncotarget. 2017 Jul 11;8(28):45286-45297. doi: 10.18632/oncotarget.16787.

5.

Clinical implication of Tiam1 overexpression in the prognosis of patients with serous ovarian carcinoma.

Li H, Cui X, Chen D, Yang Y, Piao J, Lin Z, Yan G, Shen D.

Oncol Lett. 2016 Nov;12(5):3492-3498. Epub 2016 Sep 5.

6.

Tiam1/Rac1 complex controls Il17a transcription and autoimmunity.

Kurdi AT, Bassil R, Olah M, Wu C, Xiao S, Taga M, Frangieh M, Buttrick T, Orent W, Bradshaw EM, Khoury SJ, Elyaman W.

Nat Commun. 2016 Oct 11;7:13048. doi: 10.1038/ncomms13048.

7.

Clinicopathological implications of Tiam1 overexpression in invasive ductal carcinoma of the breast.

Li Z, Liu Q, Piao J, Hua F, Wang J, Jin G, Lin Z, Zhang Y.

BMC Cancer. 2016 Aug 25;16(1):681. doi: 10.1186/s12885-016-2724-0.

8.

KDM4B-mediated epigenetic silencing of miRNA-615-5p augments RAB24 to facilitate malignancy of hepatoma cells.

Chen Z, Wang X, Liu R, Chen L, Yi J, Qi B, Shuang Z, Liu M, Li X, Li S, Tang H.

Oncotarget. 2017 Mar 14;8(11):17712-17725. doi: 10.18632/oncotarget.10832.

9.

Proteomic analysis of Rac1 signaling regulation by guanine nucleotide exchange factors.

Marei H, Carpy A, Macek B, Malliri A.

Cell Cycle. 2016 Aug 2;15(15):1961-74. doi: 10.1080/15384101.2016.1183852. Epub 2016 May 6.

10.

PAR3-aPKC regulates Tiam1 by modulating suppressive internal interactions.

Matsuzawa K, Akita H, Watanabe T, Kakeno M, Matsui T, Wang S, Kaibuchi K.

Mol Biol Cell. 2016 May 1;27(9):1511-23. doi: 10.1091/mbc.E15-09-0670. Epub 2016 Mar 3.

11.

Biological effects of RNAi targeted inhibiting Tiam1 gene expression on cholangiocarcinoma cells.

Cheng W, Liu Y, Zuo Z, Yin X, Jiang B, Chen D, Peng C, Yang J.

Int J Clin Exp Pathol. 2015 Dec 1;8(12):15511-26. eCollection 2015.

12.

The prognostic value of Tiam1 protein expression in head and neck squamous cell carcinoma: a retrospective study.

Yang H, Cai YC, Cao Y, Song M, An X, Xia Y, Wei J, Jiang WQ, Shi YX.

Chin J Cancer. 2015 Sep 14;34(12):614-21. doi: 10.1186/s40880-015-0053-3.

13.

Constructing de novo H2O2 signaling via induced protein proximity.

Zeng G, Zhang R, Xuan W, Wang W, Liang FS.

ACS Chem Biol. 2015 Jun 19;10(6):1404-10. doi: 10.1021/acschembio.5b00170. Epub 2015 Mar 18.

14.

MicroRNA-377 suppresses cell proliferation and invasion by inhibiting TIAM1 expression in hepatocellular carcinoma.

Chen G, Lu L, Liu C, Shan L, Yuan D.

PLoS One. 2015 Mar 4;10(3):e0117714. doi: 10.1371/journal.pone.0117714. eCollection 2015.

15.

By downregulating TIAM1 expression, microRNA-329 suppresses gastric cancer invasion and growth.

Li Z, Yu X, Wang Y, Shen J, Wu WK, Liang J, Feng F.

Oncotarget. 2015 Jul 10;6(19):17559-69.

16.

RhoC mediates epidermal growth factor-stimulated migration and invasion in head and neck squamous cell carcinoma.

Tumur Z, Katebzadeh S, Guerra C, Bhushan L, Alkam T, Henson BS.

Neoplasia. 2015 Jan;17(1):141-51. doi: 10.1016/j.neo.2014.12.002.

17.

HUWE1 ubiquitylates and degrades the RAC activator TIAM1 promoting cell-cell adhesion disassembly, migration, and invasion.

Vaughan L, Tan CT, Chapman A, Nonaka D, Mack NA, Smith D, Booton R, Hurlstone AF, Malliri A.

Cell Rep. 2015 Jan 6;10(1):88-102. doi: 10.1016/j.celrep.2014.12.012. Epub 2014 Dec 24.

18.

Light control of cellular processes by using photocaged abscisic acid.

Wright CW, Guo ZF, Liang FS.

Chembiochem. 2015 Jan 19;16(2):254-61. doi: 10.1002/cbic.201402576. Epub 2014 Dec 21.

19.

Degradation of Tiam1 by casein kinase 1 and the SCFβTrCP ubiquitin ligase controls the duration of mTOR-S6K signaling.

Magliozzi R, Kim J, Low TY, Heck AJ, Guardavaccaro D.

J Biol Chem. 2014 Oct 3;289(40):27400-9. doi: 10.1074/jbc.M114.575571. Epub 2014 Aug 14.

20.

Expression of Tiam1 predicts lymph node metastasis and poor survival of lung adenocarcinoma patients.

Liu S, Li Y, Qi W, Zhao Y, Huang A, Sheng W, Lei B, Lin P, Zhu H, Li W, Shen H.

Diagn Pathol. 2014 Mar 24;9:69. doi: 10.1186/1746-1596-9-69.

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