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Items: 1 to 20 of 27


TET1 Depletion Induces Aberrant CpG Methylation in Colorectal Cancer Cells.

Kai M, Niinuma T, Kitajima H, Yamamoto E, Harada T, Aoki H, Maruyama R, Toyota M, Sasaki Y, Sugai T, Tokino T, Nakase H, Suzuki H.

PLoS One. 2016 Dec 15;11(12):e0168281. doi: 10.1371/journal.pone.0168281. eCollection 2016.


Grb7 and Hax1 may colocalize partially to mitochondria in EGF-treated SKBR3 cells and their interaction can affect Caspase3 cleavage of Hax1.

Qian L, Bradford AM, Cooke PH, Lyons BA.

J Mol Recognit. 2016 Jul;29(7):318-33. doi: 10.1002/jmr.2533. Epub 2016 Feb 12.


The role of small adaptor proteins in the control of oncogenic signalingr driven by tyrosine kinases in human cancer.

Naudin C, Chevalier C, Roche S.

Oncotarget. 2016 Mar 8;7(10):11033-55. doi: 10.18632/oncotarget.6929. Review.


Grb10 promotes lipolysis and thermogenesis by phosphorylation-dependent feedback inhibition of mTORC1.

Liu M, Bai J, He S, Villarreal R, Hu D, Zhang C, Yang X, Liang H, Slaga TJ, Yu Y, Zhou Z, Blenis J, Scherer PE, Dong LQ, Liu F.

Cell Metab. 2014 Jun 3;19(6):967-80. doi: 10.1016/j.cmet.2014.03.018. Epub 2014 Apr 17.


Grb7 and Filamin-a associate and are colocalized to cell membrane ruffles upon EGF stimulation.

Paudyal P, Shrestha S, Madanayake T, Shuster CB, Rohrschneider LR, Rowland A, Lyons BA.

J Mol Recognit. 2013 Nov;26(11):532-41. doi: 10.1002/jmr.2297.


Dissecting GRB7-mediated signals for proliferation and migration in HER2 overexpressing breast tumor cells: GTP-ase rules.

Pradip D, Bouzyk M, Dey N, Leyland-Jones B.

Am J Cancer Res. 2013 Apr 3;3(2):173-95. Print 2013.


FLT3 signals via the adapter protein Grb10 and overexpression of Grb10 leads to aberrant cell proliferation in acute myeloid leukemia.

Kazi JU, Rönnstrand L.

Mol Oncol. 2013 Jun;7(3):402-18. doi: 10.1016/j.molonc.2012.11.003. Epub 2012 Nov 29.


Dimerization in the Grb7 protein.

Peterson TA, Benallie RL, Bradford AM, Pias SC, Yazzie J, Lor SN, Haulsee ZM, Park CK, Johnson DL, Rohrschneider LR, Spuches A, Lyons BA.

J Mol Recognit. 2012 Aug;25(8):427-34. doi: 10.1002/jmr.2205.


Novel nonphosphorylated peptides with conserved sequences selectively bind to Grb7 SH2 domain with affinity comparable to its phosphorylated ligand.

Zhang D, Shao C, Hu S, Ma S, Gao Y.

PLoS One. 2012;7(1):e29902. doi: 10.1371/journal.pone.0029902. Epub 2012 Jan 11.


Tyrosine phosphorylation of Grb14 by Tie2.

Sturk C, Dumont DJ.

Cell Commun Signal. 2010 Oct 25;8:30. doi: 10.1186/1478-811X-8-30.


Genomic organization and control of the grb7 gene family.

Lucas-Fernández E, García-Palmero I, Villalobo A.

Curr Genomics. 2008 Mar;9(1):60-8. doi: 10.2174/138920208783884847.


Mice with a disruption of the imprinted Grb10 gene exhibit altered body composition, glucose homeostasis, and insulin signaling during postnatal life.

Smith FM, Holt LJ, Garfield AS, Charalambous M, Koumanov F, Perry M, Bazzani R, Sheardown SA, Hegarty BD, Lyons RJ, Cooney GJ, Daly RJ, Ward A.

Mol Cell Biol. 2007 Aug;27(16):5871-86. Epub 2007 Jun 11.


Grb10 and Grb14: enigmatic regulators of insulin action--and more?

Holt LJ, Siddle K.

Biochem J. 2005 Jun 1;388(Pt 2):393-406. Review.


Disruption of the imprinted Grb10 gene leads to disproportionate overgrowth by an Igf2-independent mechanism.

Charalambous M, Smith FM, Bennett WR, Crew TE, Mackenzie F, Ward A.

Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8292-7. Epub 2003 Jun 26.


The Grb10/Nedd4 complex regulates ligand-induced ubiquitination and stability of the insulin-like growth factor I receptor.

Vecchione A, Marchese A, Henry P, Rotin D, Morrione A.

Mol Cell Biol. 2003 May;23(9):3363-72.


The adapter protein ZIP binds Grb14 and regulates its inhibitory action on insulin signaling by recruiting protein kinase Czeta.

Cariou B, Perdereau D, Cailliau K, Browaeys-Poly E, Béréziat V, Vasseur-Cognet M, Girard J, Burnol AF.

Mol Cell Biol. 2002 Oct;22(20):6959-70.


Role for the adaptor protein Grb10 in the activation of Akt.

Jahn T, Seipel P, Urschel S, Peschel C, Duyster J.

Mol Cell Biol. 2002 Feb;22(4):979-91.


Imprinting of human GRB10 and its mutations in two patients with Russell-Silver syndrome.

Yoshihashi H, Maeyama K, Kosaki R, Ogata T, Tsukahara M, Goto Y, Hata J, Matsuo N, Smith RJ, Kosaki K.

Am J Hum Genet. 2000 Aug;67(2):476-82. Epub 2000 Jun 12.

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