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Items: 17


Variable Virulence and Efficacy of BCG Vaccine Strains in Mice and Correlation With Genome Polymorphisms.

Zhang L, Ru HW, Chen FZ, Jin CY, Sun RF, Fan XY, Guo M, Mai JT, Xu WX, Lin QX, Liu J.

Mol Ther. 2016 Feb;24(2):398-405. doi: 10.1038/mt.2015.216.


Prospects in Mycobacterium bovis Bacille Calmette et Guérin (BCG) vaccine diversity and delivery: why does BCG fail to protect against tuberculosis?

Moliva JI, Turner J, Torrelles JB.

Vaccine. 2015 Sep 22;33(39):5035-41. doi: 10.1016/j.vaccine.2015.08.033. Review.


Models derived from in vitro analyses of spleen, liver, and lung leukocyte functions predict vaccine efficacy against the Francisella tularensis Live Vaccine Strain (LVS).

De Pascalis R, Chou AY, Ryden P, Kennett NJ, Sjöstedt A, Elkins KL.

MBio. 2014 Apr 8;5(2):e00936. doi: 10.1128/mBio.00936-13.


Identification of a new tuberculosis antigen recognized by γδ T cell receptor.

Xi X, Han X, Li L, Zhao Z.

Clin Vaccine Immunol. 2013 Apr;20(4):530-9. doi: 10.1128/CVI.00584-12.


Low cost tuberculosis vaccine antigens in capsules: expression in chloroplasts, bio-encapsulation, stability and functional evaluation in vitro.

Lakshmi PS, Verma D, Yang X, Lloyd B, Daniell H.

PLoS One. 2013;8(1):e54708. doi: 10.1371/journal.pone.0054708.


The BCG World Atlas: a database of global BCG vaccination policies and practices.

Zwerling A, Behr MA, Verma A, Brewer TF, Menzies D, Pai M.

PLoS Med. 2011 Mar;8(3):e1001012. doi: 10.1371/journal.pmed.1001012. No abstract available.


The co-operonic PE25/PPE41 protein complex of Mycobacterium tuberculosis elicits increased humoral and cell mediated immune response.

Tundup S, Pathak N, Ramanadham M, Mukhopadhyay S, Murthy KJ, Ehtesham NZ, Hasnain SE.

PLoS One. 2008;3(10):e3586. doi: 10.1371/journal.pone.0003586.


Novel genome polymorphisms in BCG vaccine strains and impact on efficacy.

Leung AS, Tran V, Wu Z, Yu X, Alexander DC, Gao GF, Zhu B, Liu J.

BMC Genomics. 2008 Sep 15;9:413. doi: 10.1186/1471-2164-9-413.


Immune response induced by three Mycobacterium bovis BCG substrains with diverse regions of deletion in a C57BL/6 mouse model.

Irwin SM, Goodyear A, Keyser A, Christensen R, Troudt JM, Taylor JL, Bohsali A, Briken V, Izzo AA.

Clin Vaccine Immunol. 2008 May;15(5):750-6. doi: 10.1128/CVI.00018-08.


The Delta fbpA mutant derived from Mycobacterium tuberculosis H37Rv has an enhanced susceptibility to intracellular antimicrobial oxidative mechanisms, undergoes limited phagosome maturation and activates macrophages and dendritic cells.

Katti MK, Dai G, Armitige LY, Rivera Marrero C, Daniel S, Singh CR, Lindsey DR, Dhandayuthapani S, Hunter RL, Jagannath C.

Cell Microbiol. 2008 Jun;10(6):1286-303. doi: 10.1111/j.1462-5822.2008.01126.x.


BCG vaccination confers poor protection against M. tuberculosis HN878-induced central nervous system disease.

Tsenova L, Harbacheuski R, Sung N, Ellison E, Fallows D, Kaplan G.

Vaccine. 2007 Jul 9;25(28):5126-32.


Evaluation of the Mtb72F polyprotein vaccine in a rabbit model of tuberculous meningitis.

Tsenova L, Harbacheuski R, Moreira AL, Ellison E, Dalemans W, Alderson MR, Mathema B, Reed SG, Skeiky YA, Kaplan G.

Infect Immun. 2006 Apr;74(4):2392-401.


Tracking antigen-specific CD8 T lymphocytes in the lungs of mice vaccinated with the Mtb72F polyprotein.

Irwin SM, Izzo AA, Dow SW, Skeiky YA, Reed SG, Alderson MR, Orme IM.

Infect Immun. 2005 Sep;73(9):5809-16.


Mycobacterium bovis BCG vaccines exhibit defects in alanine and serine catabolism.

Chen JM, Alexander DC, Behr MA, Liu J.

Infect Immun. 2003 Feb;71(2):708-16.


Cloning, expression, and immunological evaluation of two putative secreted serine protease antigens of Mycobacterium tuberculosis.

Skeiky YA, Lodes MJ, Guderian JA, Mohamath R, Bement T, Alderson MR, Reed SG.

Infect Immun. 1999 Aug;67(8):3998-4007.


Molecular cloning, expression, and immunogenicity of MTB12, a novel low-molecular-weight antigen secreted by Mycobacterium tuberculosis.

Webb JR, Vedvick TS, Alderson MR, Guderian JA, Jen SS, Ovendale PJ, Johnson SM, Reed SG, Skeiky YA.

Infect Immun. 1998 Sep;66(9):4208-14.

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