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Items: 17

1.

Calcium Signaling Pathway Is Associated with the Long-Term Clinical Response to Selective Serotonin Reuptake Inhibitors (SSRI) and SSRI with Antipsychotics in Patients with Obsessive-Compulsive Disorder.

Umehara H, Numata S, Tajima A, Nishi A, Nakataki M, Imoto I, Sumitani S, Ohmori T.

PLoS One. 2016 Jun 9;11(6):e0157232. doi: 10.1371/journal.pone.0157232.

2.

A new role of the Rac-GAP β2-chimaerin in cell adhesion reveals opposite functions in breast cancer initiation and tumor progression.

Casado-Medrano V, Barrio-Real L, García-Rostán G, Baumann M, Rocks O, Caloca MJ.

Oncotarget. 2016 May 10;7(19):28301-19. doi: 10.18632/oncotarget.8597.

3.

Update on genetics and diabetic retinopathy.

Hampton BM, Schwartz SG, Brantley MA Jr, Flynn HW Jr.

Clin Ophthalmol. 2015 Nov 23;9:2175-93. doi: 10.2147/OPTH.S94508. Review.

4.

Comprehensive molecular pathology analysis of small bowel adenocarcinoma reveals novel targets with potential for clinical utility.

Alvi MA, McArt DG, Kelly P, Fuchs MA, Alderdice M, McCabe CM, Bingham V, McGready C, Tripathi S, Emmert-Streib F, Loughrey MB, McQuaid S, Maxwell P, Hamilton PW, Turkington R, James JA, Wilson RH, Salto-Tellez M.

Oncotarget. 2015 Aug 28;6(25):20863-74.

5.

Guanine nucleotide exchange factor Dock7 mediates HGF-induced glioblastoma cell invasion via Rac activation.

Murray DW, Didier S, Chan A, Paulino V, Van Aelst L, Ruggieri R, Tran NL, Byrne AT, Symons M.

Br J Cancer. 2014 Mar 4;110(5):1307-15. doi: 10.1038/bjc.2014.39.

6.

β3-chimaerin, a novel member of the chimaerin Rac-GAP family.

Zubeldia-Brenner L, Gutierrez-Uzquiza A, Barrio-Real L, Wang H, Kazanietz MG, Leskow FC.

Mol Biol Rep. 2014;41(4):2067-76. doi: 10.1007/s11033-014-3055-3.

7.

Coordinated activation of the Rac-GAP β2-chimaerin by an atypical proline-rich domain and diacylglycerol.

Gutierrez-Uzquiza A, Colon-Gonzalez F, Leonard TA, Canagarajah BJ, Wang H, Mayer BJ, Hurley JH, Kazanietz MG.

Nat Commun. 2013;4:1849. doi: 10.1038/ncomms2834.

8.

A novel cross-talk in diacylglycerol signaling: the Rac-GAP beta2-chimaerin is negatively regulated by protein kinase Cdelta-mediated phosphorylation.

Griner EM, Caino MC, Sosa MS, Colón-González F, Chalmers MJ, Mischak H, Kazanietz MG.

J Biol Chem. 2010 May 28;285(22):16931-41. doi: 10.1074/jbc.M109.099036.

9.

Biochemical characterization of hyperactive beta2-chimaerin mutants revealed an enhanced exposure of C1 and Rac-GAP domains.

Sosa MS, Lewin NE, Choi SH, Blumberg PM, Kazanietz MG.

Biochemistry. 2009 Sep 1;48(34):8171-8. doi: 10.1021/bi9010623.

10.

Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes.

Pezzolesi MG, Poznik GD, Mychaleckyj JC, Paterson AD, Barati MT, Klein JB, Ng DP, Placha G, Canani LH, Bochenski J, Waggott D, Merchant ML, Krolewski B, Mirea L, Wanic K, Katavetin P, Kure M, Wolkow P, Dunn JS, Smiles A, Walker WH, Boright AP, Bull SB; DCCT/EDIC Research Group., Doria A, Rogus JJ, Rich SS, Warram JH, Krolewski AS.

Diabetes. 2009 Jun;58(6):1403-10. doi: 10.2337/db08-1514.

11.

T cell receptor-dependent tyrosine phosphorylation of beta2-chimaerin modulates its Rac-GAP function in T cells.

Siliceo M, Mérida I.

J Biol Chem. 2009 Apr 24;284(17):11354-63. doi: 10.1074/jbc.M806098200.

12.

The guanine nucleotide exchange factors trio, Ect2, and Vav3 mediate the invasive behavior of glioblastoma.

Salhia B, Tran NL, Chan A, Wolf A, Nakada M, Rutka F, Ennis M, McDonough WS, Berens ME, Symons M, Rutka JT.

Am J Pathol. 2008 Dec;173(6):1828-38. doi: 10.2353/ajpath.2008.080043.

13.
14.

Chimaerin and Rac regulate cell number, adherens junctions, and ERK MAP kinase signaling in the Drosophila eye.

Bruinsma SP, Cagan RL, Baranski TJ.

Proc Natl Acad Sci U S A. 2007 Apr 24;104(17):7098-103.

15.

Phospholipase Cgamma/diacylglycerol-dependent activation of beta2-chimaerin restricts EGF-induced Rac signaling.

Wang H, Yang C, Leskow FC, Sun J, Canagarajah B, Hurley JH, Kazanietz MG.

EMBO J. 2006 May 17;25(10):2062-74.

16.

The zebrafish homologue of mammalian chimerin Rac-GAPs is implicated in epiboly progression during development.

Leskow FC, Holloway BA, Wang H, Mullins MC, Kazanietz MG.

Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5373-8.

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