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Cystic Fibrosis Gene Therapy in the UK and Elsewhere.

Griesenbach U, Pytel KM, Alton EW.

Hum Gene Ther. 2015 May;26(5):266-75. doi: 10.1089/hum.2015.027. Review.


Ferret and pig models of cystic fibrosis: prospects and promise for gene therapy.

Yan Z, Stewart ZA, Sinn PL, Olsen JC, Hu J, McCray PB Jr, Engelhardt JF.

Hum Gene Ther Clin Dev. 2015 Mar;26(1):38-49. doi: 10.1089/humc.2014.154. Review.


Efficacy and immunogenicity of single-dose AdVAV intranasal anthrax vaccine compared to anthrax vaccine absorbed in an aerosolized spore rabbit challenge model.

Krishnan V, Andersen BH, Shoemaker C, Sivko GS, Tordoff KP, Stark GV, Zhang J, Feng T, Duchars M, Roberts MS.

Clin Vaccine Immunol. 2015 Apr;22(4):430-9. doi: 10.1128/CVI.00690-14.


Rapid generation of a mouse model for Middle East respiratory syndrome.

Zhao J, Li K, Wohlford-Lenane C, Agnihothram SS, Fett C, Zhao J, Gale MJ Jr, Baric RS, Enjuanes L, Gallagher T, McCray PB Jr, Perlman S.

Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):4970-5. doi: 10.1073/pnas.1323279111.


Gene transfection in high serum levels: case studies with new cholesterol based cationic gemini lipids.

Misra SK, Biswas J, Kondaiah P, Bhattacharya S.

PLoS One. 2013;8(7):e68305. doi: 10.1371/journal.pone.0068305.


Gene therapy for the treatment of cystic fibrosis.

Burney TJ, Davies JC.

Appl Clin Genet. 2012;5:29-36. doi: 10.2147/TACG.S8873.


Gene therapy: light is finally in the tunnel.

Cao H, Molday RS, Hu J.

Protein Cell. 2011 Dec;2(12):973-89. doi: 10.1007/s13238-011-1126-y. Review.


Nasal potential difference measurements to assess CFTR ion channel activity.

Rowe SM, Clancy JP, Wilschanski M.

Methods Mol Biol. 2011;741:69-86. doi: 10.1007/978-1-61779-117-8_6.


CFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium.

Zhang L, Button B, Gabriel SE, Burkett S, Yan Y, Skiadopoulos MH, Dang YL, Vogel LN, McKay T, Mengos A, Boucher RC, Collins PL, Pickles RJ.

PLoS Biol. 2009 Jul;7(7):e1000155. doi: 10.1371/journal.pbio.1000155.


Functional cystic fibrosis transmembrane conductance regulator expression in cystic fibrosis airway epithelial cells by AAV6.2-mediated segmental trans-splicing.

Song Y, Lou HH, Boyer JL, Limberis MP, Vandenberghe LH, Hackett NR, Leopold PL, Wilson JM, Crystal RG.

Hum Gene Ther. 2009 Mar;20(3):267-81. doi: 10.1089/hum.2008.173.


Detection of cystic fibrosis transmembrane conductance regulator activity in early-phase clinical trials.

Rowe SM, Accurso F, Clancy JP.

Proc Am Thorac Soc. 2007 Aug 1;4(4):387-98. Review.


Recombinant adenoviral vectors can induce expression of p73 via the E4-orf6/7 protein.

Shapiro GS, Van Peursem C, Ornelles DA, Schaack J, DeGregori J.

J Virol. 2006 Jun;80(11):5349-60.


Replicating rather than nonreplicating adenovirus-human immunodeficiency virus recombinant vaccines are better at eliciting potent cellular immunity and priming high-titer antibodies.

Peng B, Wang LR, Gómez-Román VR, Davis-Warren A, Montefiori DC, Kalyanaraman VS, Venzon D, Zhao J, Kan E, Rowell TJ, Murthy KK, Srivastava I, Barnett SW, Robert-Guroff M.

J Virol. 2005 Aug;79(16):10200-9.


Novel molecular approaches to cystic fibrosis gene therapy.

Lee TW, Matthews DA, Blair GE.

Biochem J. 2005 Apr 1;387(Pt 1):1-15. Review.


Glycocalyx restricts adenoviral vector access to apical receptors expressed on respiratory epithelium in vitro and in vivo: role for tethered mucins as barriers to lumenal infection.

Stonebraker JR, Wagner D, Lefensty RW, Burns K, Gendler SJ, Bergelson JM, Boucher RC, O'Neal WK, Pickles RJ.

J Virol. 2004 Dec;78(24):13755-68.


Novel replication-incompetent vector derived from adenovirus type 11 (Ad11) for vaccination and gene therapy: low seroprevalence and non-cross-reactivity with Ad5.

Holterman L, Vogels R, van der Vlugt R, Sieuwerts M, Grimbergen J, Kaspers J, Geelen E, van der Helm E, Lemckert A, Gillissen G, Verhaagh S, Custers J, Zuijdgeest D, Berkhout B, Bakker M, Quax P, Goudsmit J, Havenga M.

J Virol. 2004 Dec;78(23):13207-15.


Biodistribution of radioiodinated adenovirus fiber protein knob domain after intravenous injection in mice.

Awasthi V, Meinken G, Springer K, Srivastava SC, Freimuth P.

J Virol. 2004 Jun;78(12):6431-8.


Adenovirus type 11 uses CD46 as a cellular receptor.

Segerman A, Atkinson JP, Marttila M, Dennerquist V, Wadell G, Arnberg N.

J Virol. 2003 Sep;77(17):9183-91.

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