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Combining thioridazine and loratadine for the treatment of gastrointestinal tumor.

Chen T, Hu Y, Liu B, Huang X, Li Q, Gao N, Jin Z, Jia T, Guo D, Jin G.

Oncol Lett. 2017 Oct;14(4):4573-4580. doi: 10.3892/ol.2017.6815. Epub 2017 Aug 24.


Profile of Michael N. Hall, 2017 Albert Lasker Basic Medical Research Awardee: Target of rapamycin, cell growth, and translational control.

Sonenberg N.

Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):11564-11567. doi: 10.1073/pnas.1716203114. Epub 2017 Oct 19. No abstract available.


Twenty-five years of mTOR: Uncovering the link from nutrients to growth.

Sabatini DM.

Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):11818-11825. doi: 10.1073/pnas.1716173114. Epub 2017 Oct 25.


High mTOR activity is a hallmark of reactive natural killer cells and amplifies early signaling through activating receptors.

Marçais A, Marotel M, Degouve S, Koenig A, Fauteux-Daniel S, Drouillard A, Schlums H, Viel S, Besson L, Allatif O, Bléry M, Vivier E, Bryceson Y, Thaunat O, Walzer T.

Elife. 2017 Sep 6;6. pii: e26423. doi: 10.7554/eLife.26423.


The Architecture of the Rag GTPase Signaling Network.

Nicastro R, Sardu A, Panchaud N, De Virgilio C.

Biomolecules. 2017 Jun 30;7(3). pii: E48. doi: 10.3390/biom7030048. Review.


Auxin Signaling in Regulation of Plant Translation Reinitiation.

Schepetilnikov M, Ryabova LA.

Front Plant Sci. 2017 Jun 14;8:1014. doi: 10.3389/fpls.2017.01014. eCollection 2017. Review.


Control of B lymphocyte development and functions by the mTOR signaling pathways.

Iwata TN, Ramírez-Komo JA, Park H, Iritani BM.

Cytokine Growth Factor Rev. 2017 Jun;35:47-62. doi: 10.1016/j.cytogfr.2017.04.005. Epub 2017 May 22. Review.


The TOR Pathway Is Involved in Adventitious Root Formation in Arabidopsis and Potato.

Deng K, Dong P, Wang W, Feng L, Xiong F, Wang K, Zhang S, Feng S, Wang B, Zhang J, Ren M.

Front Plant Sci. 2017 May 12;8:784. doi: 10.3389/fpls.2017.00784. eCollection 2017.


Mammalian SWI/SNF Enzymes and the Epigenetics of Tumor Cell Metabolic Reprogramming.

Nickerson JA, Wu Q, Imbalzano AN.

Front Oncol. 2017 Apr 4;7:49. doi: 10.3389/fonc.2017.00049. eCollection 2017. Review.


Rab7 GTPase controls lipid metabolic signaling in myeloid-derived suppressor cells.

Ding X, Zhang W, Zhao T, Yan C, Du H.

Oncotarget. 2017 May 2;8(18):30123-30137. doi: 10.18632/oncotarget.16280.


Genetic visualization of protein interactions harnessing liquid phase transitions.

Watanabe T, Seki T, Fukano T, Sakaue-Sawano A, Karasawa S, Kubota M, Kurokawa H, Inoue K, Akatsuka J, Miyawaki A.

Sci Rep. 2017 Apr 13;7:46380. doi: 10.1038/srep46380.


mTOR function and therapeutic targeting in breast cancer.

Hare SH, Harvey AJ.

Am J Cancer Res. 2017 Mar 1;7(3):383-404. eCollection 2017. Review.


mTOR Signaling in Growth, Metabolism, and Disease.

Saxton RA, Sabatini DM.

Cell. 2017 Mar 9;168(6):960-976. doi: 10.1016/j.cell.2017.02.004. Review. Erratum in: Cell. 2017 Apr 6;169(2):361-371.


Disruption of the vacuolar-type H+-ATPase complex in liver causes MTORC1-independent accumulation of autophagic vacuoles and lysosomes.

Kissing S, Rudnik S, Damme M, Lüllmann-Rauch R, Ichihara A, Kornak U, Eskelinen EL, Jabs S, Heeren J, De Brabander JK, Haas A, Saftig P.

Autophagy. 2017 Apr 3;13(4):670-685. doi: 10.1080/15548627.2017.1280216. Epub 2017 Jan 27.


Mammalian target of rapamycin (mTOR): a central regulator of male fertility?

Jesus TT, Oliveira PF, Sousa M, Cheng CY, Alves MG.

Crit Rev Biochem Mol Biol. 2017 Jun;52(3):235-253. doi: 10.1080/10409238.2017.1279120. Epub 2017 Jan 26. Review.


Muscle-specific deletion of BDK amplifies loss of myofibrillar protein during protein undernutrition.

Ishikawa T, Kitaura Y, Kadota Y, Morishita Y, Ota M, Yamanaka F, Xu M, Ikawa M, Inoue N, Kawano F, Nakai N, Murakami T, Miura S, Hatazawa Y, Kamei Y, Shimomura Y.

Sci Rep. 2017 Jan 4;7:39825. doi: 10.1038/srep39825.


Tomato FK506 Binding Protein 12KD (FKBP12) Mediates the Interaction between Rapamycin and Target of Rapamycin (TOR).

Xiong F, Dong P, Liu M, Xie G, Wang K, Zhuo F, Feng L, Yang L, Li Z, Ren M.

Front Plant Sci. 2016 Nov 18;7:1746. eCollection 2016.


mTORC1 and mTORC2 in cancer and the tumor microenvironment.

Kim LC, Cook RS, Chen J.

Oncogene. 2017 Apr 20;36(16):2191-2201. doi: 10.1038/onc.2016.363. Epub 2016 Oct 17. Review.


The role of Sema4A in angiogenesis, immune responses, carcinogenesis, and retinal systems.

Ito D, Kumanogoh A.

Cell Adh Migr. 2016 Nov;10(6):692-699. Epub 2016 Oct 13. Review.


Mechanistic target of rapamycin modulation: an emerging therapeutic approach in a wide variety of disease processes.

Ferro A.

Br J Clin Pharmacol. 2016 Nov;82(5):1156-1157. doi: 10.1111/bcp.13117. No abstract available.

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