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The prevalence of abnormal leukocyte count, and its predisposing factors, in patients with sickle cell disease in Saudi Arabia.

Ahmed AE, Ali YZ, Al-Suliman AM, Albagshi JM, Al Salamah M, Elsayid M, Alanazi WR, Ahmed RA, McClish DK, Al-Jahdali H.

J Blood Med. 2017 Oct 25;8:185-191. doi: 10.2147/JBM.S148463. eCollection 2017.


Assessment of patient-controlled analgesia versus intermittent opioid therapy to manage sickle-cell disease vaso-occlusive crisis in adult patients.

Al-Anazi A, Al-Swaidan L, Al-Ammari M, Al-Debasi T, Alkatheri AM, Al-Harbi S, Obaidat AA, Al-Bekairy AM.

Saudi J Anaesth. 2017 Oct-Dec;11(4):437-441. doi: 10.4103/sja.SJA_228_17.


The endothelin B receptor plays a crucial role in the adhesion of neutrophils to the endothelium in sickle cell disease.

Koehl B, Nivoit P, El Nemer W, Lenoir O, Hermand P, Pereira C, Brousse V, Guyonnet L, Ghinatti G, Benkerrou M, Colin Y, Le Van Kim C, Tharaux PL.

Haematologica. 2017 Jul;102(7):1161-1172. doi: 10.3324/haematol.2016.156869. Epub 2017 Apr 6.


Hydroxycarbamine: from an Old Drug Used in Malignant Hemopathies to a Current Standard in Sickle Cell Disease.

Cannas G, Poutrel S, Thomas X.

Mediterr J Hematol Infect Dis. 2017 Feb 15;9(1):e2017015. doi: 10.4084/MJHID.2017.015. eCollection 2017. Review.


Intravascular hemolysis and the pathophysiology of sickle cell disease.

Kato GJ, Steinberg MH, Gladwin MT.

J Clin Invest. 2017 Mar 1;127(3):750-760. doi: 10.1172/JCI89741. Epub 2017 Mar 1. Review.


Pulmonary function in children and adolescents with sickle cell disease: have we paid proper attention to this problem?

Vieira AK, Alvim CG, Carneiro MC, Ibiapina CD.

J Bras Pneumol. 2016 Nov-Dec;42(6):409-415. doi: 10.1590/S1806-37562016000000057. English, Portuguese.


Secondhand Smoke Is an Important Modifiable Risk Factor in Sickle Cell Disease: A Review of the Current Literature and Areas for Future Research.

Sadreameli SC, Kopp BT, Creary SE, Eakin MN, McGrath-Morrow S, Strouse JJ.

Int J Environ Res Public Health. 2016 Nov 12;13(11). pii: E1131. Review.


Score Predicting Acute Chest Syndrome During Vaso-occlusive Crises in Adult Sickle-cell Disease Patients.

Bartolucci P, Habibi A, Khellaf M, Roudot-Thoraval F, Melica G, Lascaux AS, Moutereau S, Loric S, Wagner-Ballon O, Berkenou J, Santin A, Michel M, Renaud B, Lévy Y, Galactéros F, Godeau B.

EBioMedicine. 2016 Aug;10:305-11. doi: 10.1016/j.ebiom.2016.06.038. Epub 2016 Jun 29.


Targeting Mac-1-mediated leukocyte-RBC interactions uncouples the benefits for acute vaso-occlusion and chronic organ damage.

Chen G, Chang J, Zhang D, Pinho S, Jang JE, Frenette PS.

Exp Hematol. 2016 Oct;44(10):940-6. doi: 10.1016/j.exphem.2016.06.252. Epub 2016 Jul 5.


Evolving locally appropriate models of care for indian sickle cell disease.

Serjeant GR.

Indian J Med Res. 2016 Apr;143(4):405-13. doi: 10.4103/0971-5916.184282. Review.


The intersection between asthma and acute chest syndrome in children with sickle-cell anaemia.

DeBaun MR, Strunk RC.

Lancet. 2016 Jun 18;387(10037):2545-53. doi: 10.1016/S0140-6736(16)00145-8. Review.


Treating hemoglobinopathies using gene-correction approaches: promises and challenges.

Cottle RN, Lee CM, Bao G.

Hum Genet. 2016 Sep;135(9):993-1010. doi: 10.1007/s00439-016-1696-0. Epub 2016 Jun 17. Review.


Pattern of Lung Function Is Not Associated with Prior or Future Morbidity in Children with Sickle Cell Anemia.

Cohen RT, Strunk RC, Rodeghier M, Rosen CL, Kirkham FJ, Kirkby J, DeBaun MR.

Ann Am Thorac Soc. 2016 Aug;13(8):1314-23. doi: 10.1513/AnnalsATS.201510-706OC.


Customizing the genome as therapy for the β-hemoglobinopathies.

Canver MC, Orkin SH.

Blood. 2016 May 26;127(21):2536-45. doi: 10.1182/blood-2016-01-678128. Epub 2016 Apr 6. Review.


Minireview: Multiomic candidate biomarkers for clinical manifestations of sickle cell severity: Early steps to precision medicine.

Goodman SR, Pace BS, Hansen KC, D'alessandro A, Xia Y, Daescu O, Glatt SJ.

Exp Biol Med (Maywood). 2016 Apr;241(7):772-81. doi: 10.1177/1535370216640150. Epub 2016 Mar 27. Review.


Regulation of the fetal hemoglobin silencing factor BCL11A.

Basak A, Sankaran VG.

Ann N Y Acad Sci. 2016 Mar;1368(1):25-30. doi: 10.1111/nyas.13024. Epub 2016 Mar 9. Review.


Complications of sickle cell anaemia in children in Northwestern Tanzania.

Saidi H, Smart LR, Kamugisha E, Ambrose EE, Soka D, Peck RN, Makani J.

Hematology. 2016 May;21(4):248-256. doi: 10.1080/10245332.2015.1101976. Epub 2016 Feb 17.


Novel insights in the management of sickle cell disease in childhood.

Iughetti L, Bigi E, Venturelli D.

World J Clin Pediatr. 2016 Feb 8;5(1):25-34. doi: 10.5409/wjcp.v5.i1.25. eCollection 2016 Feb 8. Review.


Neutrophils, platelets, and inflammatory pathways at the nexus of sickle cell disease pathophysiology.

Zhang D, Xu C, Manwani D, Frenette PS.

Blood. 2016 Feb 18;127(7):801-9. doi: 10.1182/blood-2015-09-618538. Epub 2016 Jan 12. Review.

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