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TNF blockade induces a dysregulated type I interferon response without autoimmunity in paradoxical psoriasis.

Conrad C, Di Domizio J, Mylonas A, Belkhodja C, Demaria O, Navarini AA, Lapointe AK, French LE, Vernez M, Gilliet M.

Nat Commun. 2018 Jan 2;9(1):25. doi: 10.1038/s41467-017-02466-4.


Misoprostol Inhibits Lipopolysaccharide-Induced Pro-inflammatory Cytokine Production by Equine Leukocytes.

Martin EM, Messenger KM, Sheats MK, Jones SL.

Front Vet Sci. 2017 Sep 28;4:160. doi: 10.3389/fvets.2017.00160. eCollection 2017.


Class A CpG Oligonucleotide Priming Rescues Mice from Septic Shock via Activation of Platelet-Activating Factor Acetylhydrolase.

Yamamoto Y, Sugimura R, Watanabe T, Shigemori S, Okajima T, Nigar S, Namai F, Sato T, Ogita T, Shimosato T.

Front Immunol. 2017 Aug 30;8:1049. doi: 10.3389/fimmu.2017.01049. eCollection 2017.


Transfusion of Red Blood Cells to Patients with Sepsis.

Chan YL, Han ST, Li CH, Wu CC, Chen KF.

Int J Mol Sci. 2017 Sep 11;18(9). pii: E1946. doi: 10.3390/ijms18091946. Review.


Time-dependent proteomic and genomic alterations in Toll-like receptor-4-activated human chondrocytes: increased expression of lamin A/C and annexins.

Ha SH, Kim HK, Anh NTT, Kim N, Ko KS, Rhee BD, Han J.

Korean J Physiol Pharmacol. 2017 Sep;21(5):531-546. doi: 10.4196/kjpp.2017.21.5.531. Epub 2017 Aug 22.


Pyrin-only protein 2 limits inflammation but improves protection against bacteria.

Periasamy S, Porter KA, Atianand MK, T Le H, Earley S, Duffy EB, Haller MC, Chin H, Harton JA.

Nat Commun. 2017 Jun 5;8:15564. doi: 10.1038/ncomms15564.


The meteorology of cytokine storms, and the clinical usefulness of this knowledge.

Clark IA, Vissel B.

Semin Immunopathol. 2017 Jul;39(5):505-516. doi: 10.1007/s00281-017-0628-y. Epub 2017 Apr 27. Review.


Cheminformatics-aided discovery of small-molecule Protein-Protein Interaction (PPI) dual inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL).

Melagraki G, Ntougkos E, Rinotas V, Papaneophytou C, Leonis G, Mavromoustakos T, Kontopidis G, Douni E, Afantitis A, Kollias G.

PLoS Comput Biol. 2017 Apr 20;13(4):e1005372. doi: 10.1371/journal.pcbi.1005372. eCollection 2017 Apr.


miR-718 represses proinflammatory cytokine production through targeting phosphatase and tensin homolog (PTEN).

Kalantari P, Harandi OF, Agarwal S, Rus F, Kurt-Jones EA, Fitzgerald KA, Caffrey DR, Golenbock DT.

J Biol Chem. 2017 Apr 7;292(14):5634-5644. doi: 10.1074/jbc.M116.749325. Epub 2017 Feb 16.


The role of tumour necrosis factor in hepatitis B infection: Jekyll and Hyde.

Valaydon Z, Pellegrini M, Thompson A, Desmond P, Revill P, Ebert G.

Clin Transl Immunology. 2016 Dec 9;5(12):e115. doi: 10.1038/cti.2016.68. eCollection 2016 Dec. Review.


Common Adverse Effects of Anti-TNF Agents on Gestation.

Fasoulakis Z, Antsaklis P, Galanopoulos N, Kontomanolis E.

Obstet Gynecol Int. 2016;2016:8648651. doi: 10.1155/2016/8648651. Epub 2016 Dec 1. Review.


The diverse roles of the TNF axis in cancer progression and metastasis.

Ham B, Fernandez MC, D'Costa Z, Brodt P.

Trends Cancer Res. 2016 Jan 1;11(1):1-27.


DNA Methylation Variation Trends during the Embryonic Development of Chicken.

Li S, Zhu Y, Zhi L, Han X, Shen J, Liu Y, Yao J, Yang X.

PLoS One. 2016 Jul 20;11(7):e0159230. doi: 10.1371/journal.pone.0159230. eCollection 2016.


Carbamylated LL-37 as a modulator of the immune response.

Koro C, Hellvard A, Delaleu N, Binder V, Scavenius C, Bergum B, Główczyk I, Roberts HM, Chapple IL, Grant MM, Rapala-Kozik M, Klaga K, Enghild JJ, Potempa J, Mydel P.

Innate Immun. 2016 Apr;22(3):218-29. doi: 10.1177/1753425916631404. Epub 2016 Feb 15.


Blimp-1-Dependent IL-10 Production by Tr1 Cells Regulates TNF-Mediated Tissue Pathology.

Montes de Oca M, Kumar R, de Labastida Rivera F, Amante FH, Sheel M, Faleiro RJ, Bunn PT, Best SE, Beattie L, Ng SS, Edwards CL, Muller W, Cretney E, Nutt SL, Smyth MJ, Haque A, Hill GR, Sundar S, Kallies A, Engwerda CR.

PLoS Pathog. 2016 Jan 14;12(1):e1005398. doi: 10.1371/journal.ppat.1005398. eCollection 2016 Jan. Erratum in: PLoS Pathog. 2016 Feb;12(2):e1005460.


Impact of treatment with biologic DMARDs on the risk of sepsis or mortality after serious infection in patients with rheumatoid arthritis.

Richter A, Listing J, Schneider M, Klopsch T, Kapelle A, Kaufmann J, Zink A, Strangfeld A.

Ann Rheum Dis. 2016 Sep;75(9):1667-73. doi: 10.1136/annrheumdis-2015-207838. Epub 2015 Nov 13.


Protective role of murine norovirus against Pseudomonas aeruginosa acute pneumonia.

Thépaut M, Grandjean T, Hober D, Lobert PE, Bortolotti P, Faure K, Dessein R, Kipnis E, Guery B.

Vet Res. 2015 Sep 4;46:91. doi: 10.1186/s13567-015-0239-3.


Genetically modified "obligate" anaerobic Salmonella typhimurium as a therapeutic strategy for neuroblastoma.

Guo ZL, Yu B, Ning BT, Chan S, Lin QB, Li JC, Huang JD, Chan GC.

J Hematol Oncol. 2015 Aug 19;8:99. doi: 10.1186/s13045-015-0196-3.


A Neurologist's Guide to TNF Biology and to the Principles behind the Therapeutic Removal of Excess TNF in Disease.

Clark IA, Vissel B.

Neural Plast. 2015;2015:358263. doi: 10.1155/2015/358263. Epub 2015 Jul 22. Review.


From historical perspectives to modern therapy: a review of current and future biological treatments for Crohn's disease.

Randall CW, Vizuete JA, Martinez N, Alvarez JJ, Garapati KV, Malakouti M, Taboada CM.

Therap Adv Gastroenterol. 2015 May;8(3):143-59. doi: 10.1177/1756283X15576462. Review.

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