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Computational and biochemical characterization of two partially overlapping interfaces and multiple weak-affinity K-Ras dimers.

Prakash P, Sayyed-Ahmad A, Cho KJ, Dolino DM, Chen W, Li H, Grant BJ, Hancock JF, Gorfe AA.

Sci Rep. 2017 Jan 9;7:40109. doi: 10.1038/srep40109.


A Single Nucleotide Polymorphism in the RASGRF2 Gene Is Associated with Alcoholic Liver Cirrhosis in Men.

Novo-Veleiro I, Cieza-Borrella C, Pastor I, Chamorro AJ, Laso FJ, González-Sarmiento R, Marcos M.

PLoS One. 2016 Dec 19;11(12):e0168685. doi: 10.1371/journal.pone.0168685.


Quercetin as an Emerging Anti-Melanoma Agent: A Four-Focus Area Therapeutic Development Strategy.

Harris Z, Donovan MG, Branco GM, Limesand KH, Burd R.

Front Nutr. 2016 Oct 31;3:48. Review.


Targeting the KRAS Pathway in Non-Small Cell Lung Cancer.

Tomasini P, Walia P, Labbe C, Jao K, Leighl NB.

Oncologist. 2016 Dec;21(12):1450-1460. Review.


Structural basis of recognition of farnesylated and methylated KRAS4b by PDEδ.

Dharmaiah S, Bindu L, Tran TH, Gillette WK, Frank PH, Ghirlando R, Nissley DV, Esposito D, McCormick F, Stephen AG, Simanshu DK.

Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):E6766-E6775.


Exome chip analyses in adult attention deficit hyperactivity disorder.

Zayats T, Jacobsen KK, Kleppe R, Jacob CP, Kittel-Schneider S, Ribasés M, Ramos-Quiroga JA, Richarte V, Casas M, Mota NR, Grevet EH, Klein M, Corominas J, Bralten J, Galesloot T, Vasquez AA, Herms S, Forstner AJ, Larsson H, Breen G, Asherson P, Gross-Lesch S, Lesch KP, Cichon S, Gabrielsen MB, Holmen OL, Bau CH, Buitelaar J, Kiemeney L, Faraone SV, Cormand B, Franke B, Reif A, Haavik J, Johansson S.

Transl Psychiatry. 2016 Oct 18;6(10):e923. doi: 10.1038/tp.2016.196.


Molecular Diagnostic Applications in Colorectal Cancer.

Huth L, Jäkel J, Dahl E.

Microarrays (Basel). 2014 Jun 26;3(3):168-79. doi: 10.3390/microarrays3030168. Review.


KRAS mutation leads to decreased expression of regulator of calcineurin 2, resulting in tumor proliferation in colorectal cancer.

Niitsu H, Hinoi T, Kawaguchi Y, Sentani K, Yuge R, Kitadai Y, Sotomaru Y, Adachi T, Saito Y, Miguchi M, Kochi M, Sada H, Shimomura M, Oue N, Yasui W, Ohdan H.

Oncogenesis. 2016 Aug 15;5(8):e253. doi: 10.1038/oncsis.2016.47.


Oncogenic Ras triggers hyperproliferation and impairs polarized colonic morphogenesis by autocrine ErbB3 signaling.

Möller Y, Morkel M, Schmid J, Beyes S, Hendrick J, Strotbek M, Riemer P, Schmid S, Schmitt LC, Kontermann R, Mürdter T, Schwab M, Sers C, Olayioye MA.

Oncotarget. 2016 Aug 16;7(33):53526-53539. doi: 10.18632/oncotarget.10658.


Regulation of K-Ras4B Membrane Binding by Calmodulin.

Sperlich B, Kapoor S, Waldmann H, Winter R, Weise K.

Biophys J. 2016 Jul 12;111(1):113-22. doi: 10.1016/j.bpj.2016.05.042.


Drugging Ras GTPase: a comprehensive mechanistic and signaling structural view.

Lu S, Jang H, Gu S, Zhang J, Nussinov R.

Chem Soc Rev. 2016 Sep 21;45(18):4929-52. doi: 10.1039/c5cs00911a.


Therapeutic Approaches to RAS Mutation.

Scott AJ, Lieu CH, Messersmith WA.

Cancer J. 2016 May-Jun;22(3):165-74. doi: 10.1097/PPO.0000000000000187. Review.


Reverse engineering GTPase programming languages with reconstituted signaling networks.

Coyle SM.

Small GTPases. 2016 Jul 2;7(3):168-72. doi: 10.1080/21541248.2016.1178367.


Effects of endotoxin on expression of ras, p53 and bcl-2 oncoprotein in hepatocarcinogenesis induced by thioacetamide in rats.

Yang JM, Han DW, Liang QC, Zhao JL, Hao SY, Ma XH, Zhao YC.

World J Gastroenterol. 1997 Dec 15;3(4):213-7. doi: 10.3748/wjg.v3.i4.213.


Invited review: Activation of G proteins by GTP and the mechanism of Gα-catalyzed GTP hydrolysis.

Sprang SR.

Biopolymers. 2016 Aug;105(8):449-62. doi: 10.1002/bip.22836. Review.


Kras is Required for Adult Hematopoiesis.

Damnernsawad A, Kong G, Wen Z, Liu Y, Rajagopalan A, You X, Wang J, Zhou Y, Ranheim EA, Luo HR, Chang Q, Zhang J.

Stem Cells. 2016 Jul;34(7):1859-71. doi: 10.1002/stem.2355.


Intrinsic GTP hydrolysis is observed for a switch 1 variant of Cdc42 in the presence of a specific GTPase inhibitor.

Morris KM, Henderson R, Suresh Kumar TK, Heyes CD, Adams PD.

Small GTPases. 2016;7(1):1-11. doi: 10.1080/21541248.2015.1123797.

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