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Items: 1 to 20 of 53


Perspectives on Intra- and Intercellular Trafficking of Hedgehog for Tissue Patterning.

Simon E, Aguirre-Tamaral A, Aguilar G, Guerrero I.

J Dev Biol. 2016 Dec 2;4(4). pii: E34. doi: 10.3390/jdb4040034. Review.


Emerging Roles of DYRK Kinases in Embryogenesis and Hedgehog Pathway Control.

Singh R, Lauth M.

J Dev Biol. 2017 Nov 21;5(4). pii: E13. doi: 10.3390/jdb5040013. Review.


Hedgehog mediated degradation of Ihog adhesion proteins modulates cell segregation in Drosophila wing imaginal discs.

Hsia EYC, Zhang Y, Tran HS, Lim A, Chou YH, Lan G, Beachy PA, Zheng X.

Nat Commun. 2017 Nov 2;8(1):1275. doi: 10.1038/s41467-017-01364-z.


Cytoneme-mediated cell-cell contacts for Hedgehog reception.

González-Méndez L, Seijo-Barandiarán I, Guerrero I.

Elife. 2017 Aug 21;6. pii: e24045. doi: 10.7554/eLife.24045.


Mechanism of inhibition of the tumor suppressor Patched by Sonic Hedgehog.

Tukachinsky H, Petrov K, Watanabe M, Salic A.

Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):E5866-E5875. Epub 2016 Sep 19.


MicroRNAs in liver fibrosis: Focusing on the interaction with hedgehog signaling.

Hyun J, Jung Y.

World J Gastroenterol. 2016 Aug 7;22(29):6652-62. doi: 10.3748/wjg.v22.i29.6652. Review.


Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling.

Huang P, Nedelcu D, Watanabe M, Jao C, Kim Y, Liu J, Salic A.

Cell. 2016 Aug 25;166(5):1176-1187.e14. doi: 10.1016/j.cell.2016.08.003. Epub 2016 Aug 18.


Activities of the Cytoplasmic Domains of Patched-1 Modulate but Are Not Essential for the Regulation of Canonical Hedgehog Signaling.

Fleet A, Lee JP, Tamachi A, Javeed I, Hamel PA.

J Biol Chem. 2016 Aug 19;291(34):17557-68. doi: 10.1074/jbc.M116.731745. Epub 2016 Jun 20.


Modeling congenital disease and inborn errors of development in Drosophila melanogaster.

Moulton MJ, Letsou A.

Dis Model Mech. 2016 Mar;9(3):253-69. doi: 10.1242/dmm.023564. Review.


The Hedgehog signalling pathway in bone formation.

Yang J, Andre P, Ye L, Yang YZ.

Int J Oral Sci. 2015 Jun 26;7(2):73-9. doi: 10.1038/ijos.2015.14. Review.


Injury-stimulated Hedgehog signaling promotes regenerative proliferation of Drosophila intestinal stem cells.

Tian A, Shi Q, Jiang A, Li S, Wang B, Jiang J.

J Cell Biol. 2015 Mar 16;208(6):807-19. doi: 10.1083/jcb.201409025. Epub 2015 Mar 9.


Smoothened goes molecular: new pieces in the hedgehog signaling puzzle.

McCabe JM, Leahy DJ.

J Biol Chem. 2015 Feb 6;290(6):3500-7. doi: 10.1074/jbc.R114.617936. Epub 2014 Dec 17. Review.


Hedgehog induces formation of PKA-Smoothened complexes to promote Smoothened phosphorylation and pathway activation.

Li S, Ma G, Wang B, Jiang J.

Sci Signal. 2014 Jul 1;7(332):ra62. doi: 10.1126/scisignal.2005414.


Context-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapy.

Aberger F, Ruiz I Altaba A.

Semin Cell Dev Biol. 2014 Sep;33:93-104. doi: 10.1016/j.semcdb.2014.05.003. Epub 2014 May 19. Review.


The Little Fly that Could: Wizardry and Artistry of Drosophila Genomics.

Ejsmont RK, Hassan BA.

Genes (Basel). 2014 May 13;5(2):385-414. doi: 10.3390/genes5020385.


Low-affinity transcription factor binding sites shape morphogen responses and enhancer evolution.

Ramos AI, Barolo S.

Philos Trans R Soc Lond B Biol Sci. 2013 Nov 11;368(1632):20130018. doi: 10.1098/rstb.2013.0018. Print 2013 Dec 19.


Essential role for ligand-dependent feedback antagonism of vertebrate hedgehog signaling by PTCH1, PTCH2 and HHIP1 during neural patterning.

Holtz AM, Peterson KA, Nishi Y, Morin S, Song JY, Charron F, McMahon AP, Allen BL.

Development. 2013 Aug;140(16):3423-34. doi: 10.1242/dev.095083.


Signaling pathway and molecular subgroups of medulloblastoma.

Li KK, Lau KM, Ng HK.

Int J Clin Exp Pathol. 2013 Jun 15;6(7):1211-22. Print 2013. Review. Erratum in: Int J Clin Exp Pathol. 2015;8(9):11945.


The Drosophila WIF1 homolog Shifted maintains glypican-independent Hedgehog signaling and interacts with the Hedgehog co-receptors Ihog and Boi.

Avanesov A, Blair SS.

Development. 2013 Jan 1;140(1):107-16. doi: 10.1242/dev.078444. Epub 2012 Nov 15.


The Hedgehog signal transduction network.

Robbins DJ, Fei DL, Riobo NA.

Sci Signal. 2012 Oct 16;5(246):re6. doi: 10.1126/scisignal.2002906. Review.

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