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Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases.

Man SM, Karki R, Kanneganti TD.

Immunol Rev. 2017 May;277(1):61-75. doi: 10.1111/imr.12534. Review.


Differential roles of caspase-1 and caspase-11 in infection and inflammation.

Man SM, Karki R, Briard B, Burton A, Gingras S, Pelletier S, Kanneganti TD.

Sci Rep. 2017 Mar 27;7:45126. doi: 10.1038/srep45126.


Roles of Caspases in Necrotic Cell Death.

Yuan J, Najafov A, Py BF.

Cell. 2016 Dec 15;167(7):1693-1704. doi: 10.1016/j.cell.2016.11.047. Review.


Growth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death.

Thurston TL, Matthews SA, Jennings E, Alix E, Shao F, Shenoy AR, Birrell MA, Holden DW.

Nat Commun. 2016 Nov 3;7:13292. doi: 10.1038/ncomms13292.


Novel perspectives on non-canonical inflammasome activation.

Diamond CE, Khameneh HJ, Brough D, Mortellaro A.

Immunotargets Ther. 2015 Jul 24;4:131-41. doi: 10.2147/ITT.S57976. eCollection 2015. Review.


Listeria monocytogenes and the Inflammasome: From Cytosolic Bacteriolysis to Tumor Immunotherapy.

Theisen E, Sauer JD.

Curr Top Microbiol Immunol. 2016;397:133-60. doi: 10.1007/978-3-319-41171-2_7.


Caspase Exploitation by Legionella pneumophila.

Krause K, Amer AO.

Front Microbiol. 2016 Apr 13;7:515. doi: 10.3389/fmicb.2016.00515. eCollection 2016. Review.


Neutrophil and Alveolar Macrophage-Mediated Innate Immune Control of Legionella pneumophila Lung Infection via TNF and ROS.

Ziltener P, Reinheckel T, Oxenius A.

PLoS Pathog. 2016 Apr 22;12(4):e1005591. doi: 10.1371/journal.ppat.1005591. eCollection 2016 Apr.


Aging is associated with hypermethylation of autophagy genes in macrophages.

Khalil H, Tazi M, Caution K, Ahmed A, Kanneganti A, Assani K, Kopp B, Marsh C, Dakhlallah D, Amer AO.

Epigenetics. 2016 May 3;11(5):381-8. doi: 10.1080/15592294.2016.1144007. Epub 2016 Feb 24.


Primary Role for Toll-Like Receptor-Driven Tumor Necrosis Factor Rather than Cytosolic Immune Detection in Restricting Coxiella burnetii Phase II Replication within Mouse Macrophages.

Bradley WP, Boyer MA, Nguyen HT, Birdwell LD, Yu J, Ribeiro JM, Weiss SR, Zamboni DS, Roy CR, Shin S.

Infect Immun. 2016 Mar 24;84(4):998-1015. doi: 10.1128/IAI.01536-15. Print 2016 Apr.


The Sphingosine-1-Phosphate Lyase (LegS2) Contributes to the Restriction of Legionella pneumophila in Murine Macrophages.

Abu Khweek A, Kanneganti A, Guttridge D DC, Amer AO.

PLoS One. 2016 Jan 7;11(1):e0146410. doi: 10.1371/journal.pone.0146410. eCollection 2016.


Lyn Delivers Bacteria to Lysosomes for Eradication through TLR2-Initiated Autophagy Related Phagocytosis.

Li X, He S, Zhou X, Ye Y, Tan S, Zhang S, Li R, Yu M, Jundt MC, Hidebrand A, Wang Y, Li G, Huang C, Wu M.

PLoS Pathog. 2016 Jan 6;12(1):e1005363. doi: 10.1371/journal.ppat.1005363. eCollection 2016 Jan.


Caspase-11 and caspase-1 differentially modulate actin polymerization via RhoA and Slingshot proteins to promote bacterial clearance.

Caution K, Gavrilin MA, Tazi M, Kanneganti A, Layman D, Hoque S, Krause K, Amer AO.

Sci Rep. 2015 Dec 21;5:18479. doi: 10.1038/srep18479.


Converging roles of caspases in inflammasome activation, cell death and innate immunity.

Man SM, Kanneganti TD.

Nat Rev Immunol. 2016 Jan;16(1):7-21. doi: 10.1038/nri.2015.7. Epub 2015 Dec 14. Review.


Subversion of Cell-Autonomous Immunity and Cell Migration by Legionella pneumophila Effectors.

Simon S, Hilbi H.

Front Immunol. 2015 Sep 14;6:447. doi: 10.3389/fimmu.2015.00447. eCollection 2015. Review.


Dangerous Liaisons: Caspase-11 and Reactive Oxygen Species Crosstalk in Pathogen Elimination.

Roberts JS, Yilmaz Ӧ.

Int J Mol Sci. 2015 Sep 28;16(10):23337-54. doi: 10.3390/ijms161023337. Review.


The cytoskeleton in cell-autonomous immunity: structural determinants of host defence.

Mostowy S, Shenoy AR.

Nat Rev Immunol. 2015 Sep 15;15(9):559-73. doi: 10.1038/nri3877. Epub 2015 Aug 21. Review.


Cutting Edge: Caspase-11 Limits the Response of CD8+ T Cells to Low-Abundance and Low-Affinity Antigens.

Bergsbaken T, Bevan MJ.

J Immunol. 2015 Jul 1;195(1):41-5. doi: 10.4049/jimmunol.1500812. Epub 2015 May 15.


Human caspase-4 mediates noncanonical inflammasome activation against gram-negative bacterial pathogens.

Casson CN, Yu J, Reyes VM, Taschuk FO, Yadav A, Copenhaver AM, Nguyen HT, Collman RG, Shin S.

Proc Natl Acad Sci U S A. 2015 May 26;112(21):6688-93. doi: 10.1073/pnas.1421699112. Epub 2015 May 11.


IL-1 signaling inhibits Trichophyton rubrum conidia development and modulates the IL-17 response in vivo.

Yoshikawa FS, Ferreira LG, de Almeida SR.

Virulence. 2015;6(5):449-57. doi: 10.1080/21505594.2015.1020274. Epub 2015 May 7.

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