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Items: 1 to 20 of 55

1.

The LRRK2-macroautophagy axis and its relevance to Parkinson's disease.

Manzoni C.

Biochem Soc Trans. 2017 Feb 8;45(1):155-162. doi: 10.1042/BST20160265. Review.

2.

Autophagy regulates MAVS signaling activation in a phosphorylation-dependent manner in microglia.

Cheng J, Liao Y, Xiao L, Wu R, Zhao S, Chen H, Hou B, Zhang X, Liang C, Xu Y, Yuan Z.

Cell Death Differ. 2017 Feb;24(2):276-287. doi: 10.1038/cdd.2016.121. Epub 2016 Nov 4.

PMID:
28141795
3.

Endolysosomal dysfunction in Parkinson's disease: Recent developments and future challenges.

Kett LR, Dauer WT.

Mov Disord. 2016 Oct;31(10):1433-1443. doi: 10.1002/mds.26797.

PMID:
27619535
4.

Impairment of chaperone-mediated autophagy induces dopaminergic neurodegeneration in rats.

Xilouri M, Brekk OR, Polissidis A, Chrysanthou-Piterou M, Kloukina I, Stefanis L.

Autophagy. 2016 Nov;12(11):2230-2247. Epub 2016 Aug 19.

PMID:
27541985
5.

G2019S-LRRK2 Expression Augments α-Synuclein Sequestration into Inclusions in Neurons.

Volpicelli-Daley LA, Abdelmotilib H, Liu Z, Stoyka L, Daher JP, Milnerwood AJ, Unni VK, Hirst WD, Yue Z, Zhao HT, Fraser K, Kennedy RE, West AB.

J Neurosci. 2016 Jul 13;36(28):7415-27. doi: 10.1523/JNEUROSCI.3642-15.2016.

6.

Mechanisms of neuronal homeostasis: Autophagy in the axon.

Maday S.

Brain Res. 2016 Oct 15;1649(Pt B):143-150. doi: 10.1016/j.brainres.2016.03.047. Epub 2016 Mar 30. Review.

PMID:
27038755
7.

ULK1 and JNK are involved in mitophagy incurred by LRRK2 G2019S expression.

Zhu Y, Wang C, Yu M, Cui J, Liu L, Xu Z.

Protein Cell. 2013 Sep;4(9):711-21. doi: 10.1007/s13238-013-3910-3. Epub 2013 Sep 10.

8.

Disrupted iron homeostasis causes dopaminergic neurodegeneration in mice.

Matak P, Matak A, Moustafa S, Aryal DK, Benner EJ, Wetsel W, Andrews NC.

Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3428-35. doi: 10.1073/pnas.1519473113. Epub 2016 Feb 29.

9.

The Roles of Microtubule-Based Transport at Presynaptic Nerve Terminals.

Yagensky O, Kalantary Dehaghi T, Chua JJ.

Front Synaptic Neurosci. 2016 Feb 10;8:3. doi: 10.3389/fnsyn.2016.00003. eCollection 2016. Review.

10.

Beclin1 and HMGB1 ameliorate the α-synuclein-mediated autophagy inhibition in PC12 cells.

Wang K, Huang J, Xie W, Huang L, Zhong C, Chen Z.

Diagn Pathol. 2016 Jan 29;11:15. doi: 10.1186/s13000-016-0459-5.

11.

Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury.

Xie C, Ginet V, Sun Y, Koike M, Zhou K, Li T, Li H, Li Q, Wang X, Uchiyama Y, Truttmann AC, Kroemer G, Puyal J, Blomgren K, Zhu C.

Autophagy. 2016;12(2):410-23. doi: 10.1080/15548627.2015.1132134.

12.

Targeting the Autophagy/Lysosomal Degradation Pathway in Parkinson's Disease.

Rivero-Ríos P, Madero-Pérez J, Fernández B, Hilfiker S.

Curr Neuropharmacol. 2016;14(3):238-49. Review.

13.

Inhibition of Protein Ubiquitination by Paraquat and 1-Methyl-4-Phenylpyridinium Impairs Ubiquitin-Dependent Protein Degradation Pathways.

Navarro-Yepes J, Anandhan A, Bradley E, Bohovych I, Yarabe B, de Jong A, Ovaa H, Zhou Y, Khalimonchuk O, Quintanilla-Vega B, Franco R.

Mol Neurobiol. 2016 Oct;53(8):5229-51. doi: 10.1007/s12035-015-9414-9. Epub 2015 Sep 26.

14.

GBA deficiency promotes SNCA/α-synuclein accumulation through autophagic inhibition by inactivated PPP2A.

Du TT, Wang L, Duan CL, Lu LL, Zhang JL, Gao G, Qiu XB, Wang XM, Yang H.

Autophagy. 2015;11(10):1803-20. doi: 10.1080/15548627.2015.1086055.

15.

Impairment of autophagosome-lysosome fusion in the buff mutant mice with the VPS33A(D251E) mutation.

Zhen Y, Li W.

Autophagy. 2015;11(9):1608-22. doi: 10.1080/15548627.2015.1072669.

16.

Genetic perspective on the role of the autophagy-lysosome pathway in Parkinson disease.

Gan-Or Z, Dion PA, Rouleau GA.

Autophagy. 2015;11(9):1443-57. doi: 10.1080/15548627.2015.1067364. Review.

17.

Alpha-Synuclein affects neurite morphology, autophagy, vesicle transport and axonal degeneration in CNS neurons.

Koch JC, Bitow F, Haack J, d'Hedouville Z, Zhang JN, Tönges L, Michel U, Oliveira LM, Jovin TM, Liman J, Tatenhorst L, Bähr M, Lingor P.

Cell Death Dis. 2015 Jul 9;6:e1811. doi: 10.1038/cddis.2015.169.

18.

The Docosanoid Neuroprotectin D1 Induces TH-Positive Neuronal Survival in a Cellular Model of Parkinson's Disease.

Calandria JM, Sharp MW, Bazan NG.

Cell Mol Neurobiol. 2015 Nov;35(8):1127-36. doi: 10.1007/s10571-015-0206-6. Epub 2015 Jun 6.

19.

LRRK2 dephosphorylation increases its ubiquitination.

Zhao J, Molitor TP, Langston JW, Nichols RJ.

Biochem J. 2015 Jul 1;469(1):107-20. doi: 10.1042/BJ20141305. Epub 2015 May 5.

20.

α-Synuclein-independent histopathological and motor deficits in mice lacking the endolysosomal Parkinsonism protein Atp13a2.

Kett LR, Stiller B, Bernath MM, Tasset I, Blesa J, Jackson-Lewis V, Chan RB, Zhou B, Di Paolo G, Przedborski S, Cuervo AM, Dauer WT.

J Neurosci. 2015 Apr 8;35(14):5724-42. doi: 10.1523/JNEUROSCI.0632-14.2015.

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