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Items: 1 to 20 of 28

1.

Induction and suppression of antiviral RNA interference by influenza A virus in mammalian cells.

Li Y, Basavappa M, Lu J, Dong S, Cronkite DA, Prior JT, Reinecker HC, Hertzog P, Han Y, Li WX, Cheloufi S, Karginov FV, Ding SW, Jeffrey KL.

Nat Microbiol. 2016 Dec 5;2:16250. doi: 10.1038/nmicrobiol.2016.250.

2.

Inactivation of the type I interferon pathway reveals long double-stranded RNA-mediated RNA interference in mammalian cells.

Maillard PV, Van der Veen AG, Deddouche-Grass S, Rogers NC, Merits A, Reis E Sousa C.

EMBO J. 2016 Dec 1;35(23):2505-2518. Epub 2016 Nov 4.

3.

Design, Characterization, and Lead Selection of Therapeutic miRNAs Targeting Huntingtin for Development of Gene Therapy for Huntington's Disease.

Miniarikova J, Zanella I, Huseinovic A, van der Zon T, Hanemaaijer E, Martier R, Koornneef A, Southwell AL, Hayden MR, van Deventer SJ, Petry H, Konstantinova P.

Mol Ther Nucleic Acids. 2016 Mar 22;5:e297. doi: 10.1038/mtna.2016.7.

4.

Temporal order of RNase IIIb and loss-of-function mutations during development determines phenotype in DICER1 syndrome: a unique variant of the two-hit tumor suppression model.

Brenneman M, Field A, Yang J, Williams G, Doros L, Rossi C, Schultz KA, Rosenberg A, Ivanovich J, Turner J, Gordish-Dressman H, Stewart D, Yu W, Harris A, Schoettler P, Goodfellow P, Dehner L, Messinger Y, Hill DA.

F1000Res. 2015 Jul 10;4:214. doi: 10.12688/f1000research.6746.1. eCollection 2015.

5.

Dicer interacts with SIRT7 and regulates H3K18 deacetylation in response to DNA damaging agents.

Zhang PY, Li G, Deng ZJ, Liu LY, Chen L, Tang JZ, Wang YQ, Cao ST, Fang YX, Wen F, Xu Y, Chen X, Shi KQ, Li WF, Xie C, Tang KF.

Nucleic Acids Res. 2016 May 5;44(8):3629-42. doi: 10.1093/nar/gkv1504. Epub 2015 Dec 23.

6.

MicroRNAs: From Female Fertility, Germ Cells, and Stem Cells to Cancer in Humans.

Virant-Klun I, Ståhlberg A, Kubista M, Skutella T.

Stem Cells Int. 2016;2016:3984937. doi: 10.1155/2016/3984937. Epub 2015 Nov 9. Review.

7.

The oncogenic roles of DICER1 RNase IIIb domain mutations in ovarian Sertoli-Leydig cell tumors.

Wang Y, Chen J, Yang W, Mo F, Senz J, Yap D, Anglesio MS, Gilks B, Morin GB, Huntsman DG.

Neoplasia. 2015 Aug;17(8):650-60. doi: 10.1016/j.neo.2015.08.003.

8.

High copy number variation of cancer-related microRNA genes and frequent amplification of DICER1 and DROSHA in lung cancer.

Czubak K, Lewandowska MA, Klonowska K, Roszkowski K, Kowalewski J, Figlerowicz M, Kozlowski P.

Oncotarget. 2015 Sep 15;6(27):23399-416.

9.

The many faces of Dicer: the complexity of the mechanisms regulating Dicer gene expression and enzyme activities.

Kurzynska-Kokorniak A, Koralewska N, Pokornowska M, Urbanowicz A, Tworak A, Mickiewicz A, Figlerowicz M.

Nucleic Acids Res. 2015 May 19;43(9):4365-80. doi: 10.1093/nar/gkv328. Epub 2015 Apr 16. Review.

10.

Recurrent DGCR8, DROSHA, and SIX homeodomain mutations in favorable histology Wilms tumors.

Walz AL, Ooms A, Gadd S, Gerhard DS, Smith MA, Guidry Auvil JM, Meerzaman D, Chen QR, Hsu CH, Yan C, Nguyen C, Hu Y, Bowlby R, Brooks D, Ma Y, Mungall AJ, Moore RA, Schein J, Marra MA, Huff V, Dome JS, Chi YY, Mullighan CG, Ma J, Wheeler DA, Hampton OA, Jafari N, Ross N, Gastier-Foster JM, Perlman EJ.

Cancer Cell. 2015 Feb 9;27(2):286-97. doi: 10.1016/j.ccell.2015.01.003. Erratum in: Cancer Cell. 2015 Mar 9;27(3):426. Guidry Auvil, Jamie M [corrected to Guidry Auvil, Jaime M].

12.

Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours.

Rakheja D, Chen KS, Liu Y, Shukla AA, Schmid V, Chang TC, Khokhar S, Wickiser JE, Karandikar NJ, Malter JS, Mendell JT, Amatruda JF.

Nat Commun. 2014 Sep 5;2:4802. doi: 10.1038/ncomms5802.

13.

Germ-line and somatic DICER1 mutations in pineoblastoma.

de Kock L, Sabbaghian N, Druker H, Weber E, Hamel N, Miller S, Choong CS, Gottardo NG, Kees UR, Rednam SP, van Hest LP, Jongmans MC, Jhangiani S, Lupski JR, Zacharin M, Bouron-Dal Soglio D, Huang A, Priest JR, Perry A, Mueller S, Albrecht S, Malkin D, Grundy RG, Foulkes WD.

Acta Neuropathol. 2014 Oct;128(4):583-95. doi: 10.1007/s00401-014-1318-7. Epub 2014 Jul 15.

14.

Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop sequences.

Pugh TJ, Yu W, Yang J, Field AL, Ambrogio L, Carter SL, Cibulskis K, Giannikopoulos P, Kiezun A, Kim J, McKenna A, Nickerson E, Getz G, Hoffher S, Messinger YH, Dehner LP, Roberts CW, Rodriguez-Galindo C, Williams GM, Rossi CT, Meyerson M, Hill DA.

Oncogene. 2014 Nov 6;33(45):5295-302. doi: 10.1038/onc.2014.150. Epub 2014 Jun 9.

15.

MicroRNA Machinery Genes as Novel Biomarkers for Cancer.

Huang JT, Wang J, Srivastava V, Sen S, Liu SM.

Front Oncol. 2014 May 19;4:113. doi: 10.3389/fonc.2014.00113. eCollection 2014. Review.

16.

Pituitary blastoma: a pathognomonic feature of germ-line DICER1 mutations.

de Kock L, Sabbaghian N, Plourde F, Srivastava A, Weber E, Bouron-Dal Soglio D, Hamel N, Choi JH, Park SH, Deal CL, Kelsey MM, Dishop MK, Esbenshade A, Kuttesch JF, Jacques TS, Perry A, Leichter H, Maeder P, Brundler MA, Warner J, Neal J, Zacharin M, Korbonits M, Cole T, Traunecker H, McLean TW, Rotondo F, Lepage P, Albrecht S, Horvath E, Kovacs K, Priest JR, Foulkes WD.

Acta Neuropathol. 2014 Jul;128(1):111-22. doi: 10.1007/s00401-014-1285-z. Epub 2014 May 20.

17.

Global microRNA depletion suppresses tumor angiogenesis.

Chen S, Xue Y, Wu X, Le C, Bhutkar A, Bell EL, Zhang F, Langer R, Sharp PA.

Genes Dev. 2014 May 15;28(10):1054-67. doi: 10.1101/gad.239681.114. Epub 2014 May 1.

18.

Mammalian 5'-capped microRNA precursors that generate a single microRNA.

Xie M, Li M, Vilborg A, Lee N, Shu MD, Yartseva V, Šestan N, Steitz JA.

Cell. 2013 Dec 19;155(7):1568-80. doi: 10.1016/j.cell.2013.11.027.

19.

Synthetic pre-microRNAs reveal dual-strand activity of miR-34a on TNF-α.

Guennewig B, Roos M, Dogar AM, Gebert LF, Zagalak JA, Vongrad V, Metzner KJ, Hall J.

RNA. 2014 Jan;20(1):61-75. doi: 10.1261/rna.038968.113. Epub 2013 Nov 18.

20.

Miravirsen (SPC3649) can inhibit the biogenesis of miR-122.

Gebert LF, Rebhan MA, Crivelli SE, Denzler R, Stoffel M, Hall J.

Nucleic Acids Res. 2014 Jan;42(1):609-21. doi: 10.1093/nar/gkt852. Epub 2013 Sep 24.

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