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Items: 1 to 20 of 82

1.

Critical threshold levels of DNA methyltransferase 1 are required to maintain DNA methylation across the genome in human cancer cells.

Cai Y, Tsai HC, Yen RC, Zhang YW, Kong X, Wang W, Xia L, Baylin SB.

Genome Res. 2017 Apr;27(4):533-544. doi: 10.1101/gr.208108.116. Epub 2017 Feb 23.

PMID:
28232479
2.

Small genomic insertions form enhancers that misregulate oncogenes.

Abraham BJ, Hnisz D, Weintraub AS, Kwiatkowski N, Li CH, Li Z, Weichert-Leahey N, Rahman S, Liu Y, Etchin J, Li B, Shen S, Lee TI, Zhang J, Look AT, Mansour MR, Young RA.

Nat Commun. 2017 Feb 9;8:14385. doi: 10.1038/ncomms14385.

3.

Hotspots of aberrant enhancer activity punctuate the colorectal cancer epigenome.

Cohen AJ, Saiakhova A, Corradin O, Luppino JM, Lovrenert K, Bartels CF, Morrow JJ, Mack SC, Dhillon G, Beard L, Myeroff L, Kalady MF, Willis J, Bradner JE, Keri RA, Berger NA, Pruett-Miller SM, Markowitz SD, Scacheri PC.

Nat Commun. 2017 Feb 7;8:14400. doi: 10.1038/ncomms14400.

4.

Epigenomic landscape of 5-hydroxymethylcytosine reveals its transcriptional regulation of lncRNAs in colorectal cancer.

Hu H, Shu M, He L, Yu X, Liu X, Lu Y, Chen Y, Miao X, Chen X.

Br J Cancer. 2017 Feb 28;116(5):658-668. doi: 10.1038/bjc.2016.457. Epub 2017 Jan 31.

PMID:
28141796
5.

Extensive Association of Common Disease Variants with Regulatory Sequence.

Mokry M, Harakalova M, Asselbergs FW, de Bakker PI, Nieuwenhuis EE.

PLoS One. 2016 Nov 22;11(11):e0165893. doi: 10.1371/journal.pone.0165893. eCollection 2016.

6.

Emergence of the Noncoding Cancer Genome: A Target of Genetic and Epigenetic Alterations.

Zhou S, Treloar AE, Lupien M.

Cancer Discov. 2016 Nov;6(11):1215-1229. Epub 2016 Oct 19. Review.

PMID:
27807102
7.

Genome-Wide Interaction Analyses between Genetic Variants and Alcohol Consumption and Smoking for Risk of Colorectal Cancer.

Gong J, Hutter CM, Newcomb PA, Ulrich CM, Bien SA, Campbell PT, Baron JA, Berndt SI, Bezieau S, Brenner H, Casey G, Chan AT, Chang-Claude J, Du M, Duggan D, Figueiredo JC, Gallinger S, Giovannucci EL, Haile RW, Harrison TA, Hayes RB, Hoffmeister M, Hopper JL, Hudson TJ, Jeon J, Jenkins MA, Kocarnik J, Küry S, Le Marchand L, Lin Y, Lindor NM, Nishihara R, Ogino S, Potter JD, Rudolph A, Schoen RE, Schrotz-King P, Seminara D, Slattery ML, Thibodeau SN, Thornquist M, Toth R, Wallace R, White E, Jiao S, Lemire M, Hsu L, Peters U; CCFR and GECCO..

PLoS Genet. 2016 Oct 10;12(10):e1006296. doi: 10.1371/journal.pgen.1006296. eCollection 2016 Oct.

8.

Epigenomic profiling of primary gastric adenocarcinoma reveals super-enhancer heterogeneity.

Ooi WF, Xing M, Xu C, Yao X, Ramlee MK, Lim MC, Cao F, Lim K, Babu D, Poon LF, Lin Suling J, Qamra A, Irwanto A, Qu Zhengzhong J, Nandi T, Lee-Lim AP, Chan YS, Tay ST, Lee MH, Davies JO, Wong WK, Soo KC, Chan WH, Ong HS, Chow P, Wong CY, Rha SY, Liu J, Hillmer AM, Hughes JR, Rozen S, Teh BT, Fullwood MJ, Li S, Tan P.

Nat Commun. 2016 Sep 28;7:12983. doi: 10.1038/ncomms12983.

9.

Modeling disease risk through analysis of physical interactions between genetic variants within chromatin regulatory circuitry.

Corradin O, Cohen AJ, Luppino JM, Bayles IM, Schumacher FR, Scacheri PC.

Nat Genet. 2016 Nov;48(11):1313-1320. doi: 10.1038/ng.3674. Epub 2016 Sep 19.

10.

Improving Pathological Assessment of Breast Cancer by Employing Array-Based Transcriptome Analysis.

Mihály Z, Győrffy B.

Microarrays (Basel). 2013 Aug 29;2(3):228-42. doi: 10.3390/microarrays2030228. Review.

11.

Enhancer deregulation in cancer and other diseases.

Herz HM.

Bioessays. 2016 Oct;38(10):1003-15. doi: 10.1002/bies.201600106. Epub 2016 Aug 29.

PMID:
27570183
12.

Transcriptome-wide identification of mRNAs and lincRNAs associated with trastuzumab-resistance in HER2-positive breast cancer.

Merry CR, McMahon S, Forrest ME, Bartels CF, Saiakhova A, Bartel CA, Scacheri PC, Thompson CL, Jackson MW, Harris LN, Khalil AM.

Oncotarget. 2016 Aug 16;7(33):53230-53244. doi: 10.18632/oncotarget.10637.

13.

Identifying Liver Cancer-Related Enhancer SNPs by Integrating GWAS and Histone Modification ChIP-seq Data.

Zhang T, Hu Y, Wu X, Ma R, Jiang Q, Wang Y.

Biomed Res Int. 2016;2016:2395341. doi: 10.1155/2016/2395341. Epub 2016 Jun 27.

14.

Long-range regulators of the lncRNA HOTAIR enhance its prognostic potential in breast cancer.

Milevskiy MJ, Al-Ejeh F, Saunus JM, Northwood KS, Bailey PJ, Betts JA, McCart Reed AE, Nephew KP, Stone A, Gee JM, Dowhan DH, Dray E, Shewan AM, French JD, Edwards SL, Clark SJ, Lakhani SR, Brown MA.

Hum Mol Genet. 2016 Aug 1;25(15):3269-3283. doi: 10.1093/hmg/ddw177. Epub 2016 Jul 4.

15.

Rapid and specific hypomethylation of enhancers in endothelial cells during adaptation to cell culturing.

Magnusson M, Larsson P, Lu EX, Bergh N, Carén H, Jern S.

Epigenetics. 2016 Aug 2;11(8):614-24. doi: 10.1080/15592294.2016.1192734. Epub 2016 Jun 14.

PMID:
27302749
16.

6-Substituted 2-Aminopurine-2'-deoxyribonucleoside 5'-Triphosphates that Trace Cytosine Methylation.

von Watzdorf J, Marx A.

Chembiochem. 2016 Aug 17;17(16):1532-40. doi: 10.1002/cbic.201600245. Epub 2016 Jul 6.

17.

Interplay between diet, gut microbiota, epigenetic events, and colorectal cancer.

Bultman SJ.

Mol Nutr Food Res. 2017 Jan;61(1). doi: 10.1002/mnfr.201500902. Epub 2016 Jun 2. Review.

PMID:
27138454
18.

Three-dimensional disorganization of the cancer genome occurs coincident with long-range genetic and epigenetic alterations.

Taberlay PC, Achinger-Kawecka J, Lun AT, Buske FA, Sabir K, Gould CM, Zotenko E, Bert SA, Giles KA, Bauer DC, Smyth GK, Stirzaker C, O'Donoghue SI, Clark SJ.

Genome Res. 2016 Jun;26(6):719-31. doi: 10.1101/gr.201517.115. Epub 2016 Apr 6.

19.

Integrated analysis of long non-coding RNAs in human colorectal cancer.

Chen X, Liu B, Yang R, Guo Y, Li F, Wang L, Hu H.

Oncotarget. 2016 Apr 26;7(17):23897-908. doi: 10.18632/oncotarget.8192.

20.

Embryonic Stem Cell (ES)-Specific Enhancers Specify the Expression Potential of ES Genes in Cancer.

Aran D, Abu-Remaileh M, Levy R, Meron N, Toperoff G, Edrei Y, Bergman Y, Hellman A.

PLoS Genet. 2016 Feb 17;12(2):e1005840. doi: 10.1371/journal.pgen.1005840. eCollection 2016 Feb.

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