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Items: 1 to 20 of 51

1.

Switching between Exonucleolysis and Replication by T7 DNA Polymerase Ensures High Fidelity.

Hoekstra TP, Depken M, Lin SN, Cabanas-Danés J, Gross P, Dame RT, Peterman EJ, Wuite GJ.

Biophys J. 2017 Feb 28;112(4):575-583. doi: 10.1016/j.bpj.2016.12.044.

PMID:
28256218
2.

Kinetics of nucleotide entry into RNA polymerase active site provides mechanism for efficiency and fidelity.

Wang B, Sexton RE, Feig M.

Biochim Biophys Acta. 2017 Apr;1860(4):482-490. doi: 10.1016/j.bbagrm.2017.02.008. Epub 2017 Feb 24.

PMID:
28242207
3.

Wide-ranging and unexpected consequences of altered Pol II catalytic activity in vivo.

Malik I, Qiu C, Snavely T, Kaplan CD.

Nucleic Acids Res. 2017 May 5;45(8):4431-4451. doi: 10.1093/nar/gkx037.

4.

High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop.

Qiu C, Erinne OC, Dave JM, Cui P, Jin H, Muthukrishnan N, Tang LK, Babu SG, Lam KC, Vandeventer PJ, Strohner R, Van den Brulle J, Sze SH, Kaplan CD.

PLoS Genet. 2016 Nov 29;12(11):e1006321. doi: 10.1371/journal.pgen.1006321. eCollection 2016 Nov.

5.

Nucleosomal arrangement affects single-molecule transcription dynamics.

Fitz V, Shin J, Ehrlich C, Farnung L, Cramer P, Zaburdaev V, Grill SW.

Proc Natl Acad Sci U S A. 2016 Oct 24. pii: 201602764. [Epub ahead of print]

6.

Direct Characterization of Transcription Elongation by RNA Polymerase I.

Ucuncuoglu S, Engel KL, Purohit PK, Dunlap DD, Schneider DA, Finzi L.

PLoS One. 2016 Jul 25;11(7):e0159527. doi: 10.1371/journal.pone.0159527. eCollection 2016.

7.

Relationships Between RNA Polymerase II Activity and Spt Elongation Factors to Spt- Phenotype and Growth in Saccharomyces cerevisiae.

Cui P, Jin H, Vutukuru MR, Kaplan CD.

G3 (Bethesda). 2016 Aug 9;6(8):2489-504. doi: 10.1534/g3.116.030346.

8.

Single molecule microscopy reveals mechanistic insight into RNA polymerase II preinitiation complex assembly and transcriptional activity.

Horn AE, Kugel JF, Goodrich JA.

Nucleic Acids Res. 2016 Sep 6;44(15):7132-43. doi: 10.1093/nar/gkw321. Epub 2016 Apr 25.

9.

Functional interplay between NTP leaving group and base pair recognition during RNA polymerase II nucleotide incorporation revealed by methylene substitution.

Hwang CS, Xu L, Wang W, Ulrich S, Zhang L, Chong J, Shin JH, Huang X, Kool ET, McKenna CE, Wang D.

Nucleic Acids Res. 2016 May 5;44(8):3820-8. doi: 10.1093/nar/gkw220. Epub 2016 Apr 7.

10.

Mechanisms of backtrack recovery by RNA polymerases I and II.

Lisica A, Engel C, Jahnel M, Roldán É, Galburt EA, Cramer P, Grill SW.

Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):2946-51. doi: 10.1073/pnas.1517011113. Epub 2016 Feb 29.

11.

Lineage-specific variations in the trigger loop modulate RNA proofreading by bacterial RNA polymerases.

Esyunina D, Turtola M, Pupov D, Bass I, Klimašauskas S, Belogurov G, Kulbachinskiy A.

Nucleic Acids Res. 2016 Feb 18;44(3):1298-308. doi: 10.1093/nar/gkv1521. Epub 2016 Jan 4.

12.

RNA polymerase II transcriptional fidelity control and its functional interplay with DNA modifications.

Xu L, Wang W, Chong J, Shin JH, Xu J, Wang D.

Crit Rev Biochem Mol Biol. 2015;50(6):503-19. doi: 10.3109/10409238.2015.1087960. Epub 2015 Sep 22. Review.

13.

Real-time observation of the initiation of RNA polymerase II transcription.

Fazal FM, Meng CA, Murakami K, Kornberg RD, Block SM.

Nature. 2015 Sep 10;525(7568):274-7. doi: 10.1038/nature14882. Epub 2015 Sep 2.

14.

The fission yeast cytokinetic contractile ring regulates septum shape and closure.

Thiyagarajan S, Munteanu EL, Arasada R, Pollard TD, O'Shaughnessy B.

J Cell Sci. 2015 Oct 1;128(19):3672-81. doi: 10.1242/jcs.166926. Epub 2015 Aug 3.

15.

Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.

Barnes CO, Calero M, Malik I, Graham BW, Spahr H, Lin G, Cohen AE, Brown IS, Zhang Q, Pullara F, Trakselis MA, Kaplan CD, Calero G.

Mol Cell. 2015 Jul 16;59(2):258-69. doi: 10.1016/j.molcel.2015.06.034.

16.

Structural Model of RNA Polymerase II Elongation Complex with Complete Transcription Bubble Reveals NTP Entry Routes.

Zhang L, Silva DA, Pardo-Avila F, Wang D, Huang X.

PLoS Comput Biol. 2015 Jul 2;11(7):e1004354. doi: 10.1371/journal.pcbi.1004354. eCollection 2015 Jul.

17.

Regulation of Transcript Elongation.

Belogurov GA, Artsimovitch I.

Annu Rev Microbiol. 2015;69:49-69. doi: 10.1146/annurev-micro-091014-104047. Epub 2015 Jun 24. Review.

18.

Unfolding Kinetics of the Human Telomere i-Motif Under a 10 pN Force Imposed by the α-Hemolysin Nanopore Identify Transient Folded-State Lifetimes at Physiological pH.

Ding Y, Fleming AM, He L, Burrows CJ.

J Am Chem Soc. 2015 Jul 22;137(28):9053-60. doi: 10.1021/jacs.5b03912. Epub 2015 Jul 9.

19.

Mechano-chemical kinetics of DNA replication: identification of the translocation step of a replicative DNA polymerase.

Morin JA, Cao FJ, Lázaro JM, Arias-Gonzalez JR, Valpuesta JM, Carrascosa JL, Salas M, Ibarra B.

Nucleic Acids Res. 2015 Apr 20;43(7):3643-52. doi: 10.1093/nar/gkv204. Epub 2015 Mar 23.

20.

DNA template dependent accuracy variation of nucleotide selection in transcription.

Mellenius H, Ehrenberg M.

PLoS One. 2015 Mar 23;10(3):e0119588. doi: 10.1371/journal.pone.0119588. eCollection 2015.

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