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CRISPR/Cas9-mediated knockout of p22phox leads to loss of Nox1 and Nox4, but not Nox5 activity.

Prior KK, Leisegang MS, Josipovic I, Löwe O, Shah AM, Weissmann N, Schröder K, Brandes RP.

Redox Biol. 2016 Aug 24;9:287-295. doi: 10.1016/j.redox.2016.08.013. [Epub ahead of print]


NADPH oxidases as electrochemical generators to produce ion fluxes and turgor in fungi, plants and humans.

Segal AW.

Open Biol. 2016 May;6(5). pii: 160028. doi: 10.1098/rsob.160028. Epub 2016 May 18. Review.


Association of the NAD(P)H oxidase p22 phox gene C242T polymorphism with type 2 diabetes mellitus, diabetic nephropathy, and carotid atherosclerosis with type 2 diabetes mellitus: A meta-analysis.

Li T, Xi HF, Luo HM, Liu WX, Gao X, Liu DW, Yang L.

Meta Gene. 2015 Aug 25;6:1-8. doi: 10.1016/j.mgene.2015.07.009. eCollection 2015 Dec.


INF-γ Enhances Nox2 Activity by Upregulating phox Proteins When Applied to Differentiating PLB-985 Cells but Does Not Induce Nox2 Activity by Itself.

Ellison MA, Thurman G, Gearheart CM, Seewald RH, Porter CC, Ambruso DR.

PLoS One. 2015 Aug 28;10(8):e0136766. doi: 10.1371/journal.pone.0136766. eCollection 2015.


Identification of a Novel Mutation in the CYBB Gene, p.Asp378Gly, in a Patient With X-linked Chronic Granulomatous Disease.

Song SM, Park MR, Kim DS, Kim J, Kim YJ, Ki CS, Ahn K.

Allergy Asthma Immunol Res. 2014 Jul;6(4):366-9. doi: 10.4168/aair.2014.6.4.366. Epub 2014 Jan 20.


NOX2 As a Target for Drug Development: Indications, Possible Complications, and Progress.

Diebold BA, Smith SM, Li Y, Lambeth JD.

Antioxid Redox Signal. 2015 Aug 10;23(5):375-405. doi: 10.1089/ars.2014.5862. Epub 2014 Mar 24. Review.


Polymorphisms of C242T and A640G in CYBA gene and the risk of coronary artery disease: a meta-analysis.

Xu Q, Yuan F, Shen X, Wen H, Li W, Cheng B, Wu J.

PLoS One. 2014 Jan 2;9(1):e84251. doi: 10.1371/journal.pone.0084251. eCollection 2014.


The A930G polymorphism ofP22phox (CYBA) gene but not C242T variation is associated with hypertension: a meta-analysis.

Qin YW, Peng J, Liang BY, Su L, Chen Q, Xie JJ, Gu L.

PLoS One. 2013 Dec 9;8(12):e82465. doi: 10.1371/journal.pone.0082465. eCollection 2013.


Relationship of the p22phox (CYBA) gene polymorphism C242T with risk of coronary artery disease: a meta-analysis.

Wu Z, Lou Y, Jin W, Liu Y, Lu L, Chen Q, Xie Y, Lu G.

PLoS One. 2013 Sep 5;8(9):e70885. doi: 10.1371/journal.pone.0070885. eCollection 2013. Erratum in: PLoS One. 2013;8(12). doi:10.1371/annotation/7f489b96-e43f-4c6d-86d7-0689c8a55eba.


Molecular identification of bacterial DNA in the chorioretinal scars of chronic granulomatous disease.

Wang Y, Marciano BE, Shen D, Bishop RJ, Park S, Holland SM, Chan CC.

J Clin Immunol. 2013 Jul;33(5):917-24. doi: 10.1007/s10875-013-9899-9. Epub 2013 May 1.


Association between NADPH oxidase p22(phox) C242T polymorphism and ischemic cerebrovascular disease: a meta-analysis.

Li BH, Zhang LL, Zhang BB, Yin YW, Dai LM, Pi Y, Guo L, Gao CY, Fang CQ, Wang JZ, Li JC.

PLoS One. 2013;8(2):e56478. doi: 10.1371/journal.pone.0056478. Epub 2013 Feb 11.


Animal models of human granulocyte diseases.

Schäffer AA, Klein C.

Hematol Oncol Clin North Am. 2013 Feb;27(1):129-48, ix. doi: 10.1016/j.hoc.2012.10.005. Epub 2012 Oct 31. Review.


Nitroarachidonic acid prevents NADPH oxidase assembly and superoxide radical production in activated macrophages.

González-Perilli L, Álvarez MN, Prolo C, Radi R, Rubbo H, Trostchansky A.

Free Radic Biol Med. 2013 May;58:126-33. doi: 10.1016/j.freeradbiomed.2012.12.020. Epub 2013 Jan 11.


Redox balance dynamically regulates vascular growth and remodeling.

Bir SC, Kolluru GK, Fang K, Kevil CG.

Semin Cell Dev Biol. 2012 Sep;23(7):745-57. doi: 10.1016/j.semcdb.2012.05.003. Epub 2012 May 24. Review.


CYBA Gene Polymorphisms and Adverse Outcomes in Acute Kidney Injury: A Prospective Cohort Study.

Perianayagam MC, Tighiouart H, Nievergelt CM, O'Connor DT, Liangos O, Jaber BL.

Nephron Extra. 2011 Jan;1(1):112-23. doi: 10.1159/000333017. Epub 2011 Oct 21.


Regulation of reactive oxygen species generation in cell signaling.

Bae YS, Oh H, Rhee SG, Yoo YD.

Mol Cells. 2011 Dec;32(6):491-509. doi: 10.1007/s10059-011-0276-3. Epub 2011 Dec 22. Review.


The C242T polymorphism of the p22-phox gene (CYBA) is associated with higher left ventricular mass in Brazilian hypertensive patients.

Schreiber R, Ferreira-Sae MC, Ronchi JA, Pio-Magalhães JA, Cipolli JA, Matos-Souza JR, Mill JG, Vercesi AE, Krieger JE, Franchini KG, Pereira AC, Nadruz Junior W.

BMC Med Genet. 2011 Aug 31;12:114. doi: 10.1186/1471-2350-12-114.


Invariant local conformation in p22phox p.Y72H polymorphisms suggested by mass spectral analysis of crosslinked human neutrophil flavocytochrome b.

Taylor RM, Dratz EA, Jesaitis AJ.

Biochimie. 2011 Sep;93(9):1502-9. doi: 10.1016/j.biochi.2011.05.004. Epub 2011 May 27.


NADPH oxidase activation in pancreatic cancer cells is mediated through Akt-dependent up-regulation of p22phox.

Edderkaoui M, Nitsche C, Zheng L, Pandol SJ, Gukovsky I, Gukovskaya AS.

J Biol Chem. 2011 Mar 11;286(10):7779-87. doi: 10.1074/jbc.M110.200063. Epub 2010 Nov 30. Erratum in: J Biol Chem. 2013 Dec 20;288(51):36259. J Biol Chem. 2013 Jul 5;288(27):19648.


Towards routine screening of rare genetic diseases: the example of chronic granulomatous disease.

Stasia MJ.

J Mol Diagn. 2010 May;12(3):269-71. doi: 10.2353/jmoldx.2010.100004. Epub 2010 Mar 19. No abstract available.

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