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Items: 19


Purinergic P2X7 receptor functional genetic polymorphisms are associated with the susceptibility to osteoporosis in Chinese postmenopausal women.

Xu H, Gong C, He L, Rao S, Liu X, Nie Y, Liu C, Li T, Ding L, Tu Y, Yang Y, Hu F, Fan Y, Wang H, Wang S, Xiong C, Zhong P, Tang L, Liang S.

Purinergic Signal. 2017 Sep;13(3):339-346. doi: 10.1007/s11302-017-9566-3. Epub 2017 May 11.


Bone-associated gene evolution and the origin of flight in birds.

Machado JP, Johnson WE, Gilbert MT, Zhang G, Jarvis ED, O'Brien SJ, Antunes A.

BMC Genomics. 2016 May 18;17:371. doi: 10.1186/s12864-016-2681-7.


Functional polymorphisms in the P2X7 receptor gene are associated with stress fracture injury.

Varley I, Greeves JP, Sale C, Friedman E, Moran DS, Yanovich R, Wilson PJ, Gartland A, Hughes DC, Stellingwerff T, Ranson C, Fraser WD, Gallagher JA.

Purinergic Signal. 2016 Mar;12(1):103-13. doi: 10.1007/s11302-016-9495-6. Epub 2016 Jan 29.


Control of bone development by P2X and P2Y receptors expressed in mesenchymal and hematopoietic cells.

Lenertz LY, Baughman CJ, Waldschmidt NV, Thaler R, van Wijnen AJ.

Gene. 2015 Oct 1;570(1):1-7. doi: 10.1016/j.gene.2015.06.031. Epub 2015 Jun 14. Review.


Trophic activity of human P2X7 receptor isoforms A and B in osteosarcoma.

Giuliani AL, Colognesi D, Ricco T, Roncato C, Capece M, Amoroso F, Wang QG, De Marchi E, Gartland A, Di Virgilio F, Adinolfi E.

PLoS One. 2014 Sep 16;9(9):e107224. doi: 10.1371/journal.pone.0107224. eCollection 2014.


Non-synonymous single nucleotide polymorphisms in the P2X receptor genes: association with diseases, impact on receptor functions and potential use as diagnosis biomarkers.

Caseley EA, Muench SP, Roger S, Mao HJ, Baldwin SA, Jiang LH.

Int J Mol Sci. 2014 Jul 30;15(8):13344-71. doi: 10.3390/ijms150813344. Review.


P2X-selective purinergic antagonists are strong inhibitors of HIV-1 fusion during both cell-to-cell and cell-free infection.

Swartz TH, Esposito AM, Durham ND, Hartmann BM, Chen BK.

J Virol. 2014 Oct;88(19):11504-15. doi: 10.1128/JVI.01158-14. Epub 2014 Jul 16.


Gain and loss of function of P2X7 receptors: mechanisms, pharmacology and relevance to diabetic neuropathic pain.

Ursu D, Ebert P, Langron E, Ruble C, Munsie L, Zou W, Fijal B, Qian YW, McNearney TA, Mogg A, Grubisha O, Merchant K, Sher E.

Mol Pain. 2014 Jun 16;10:37. doi: 10.1186/1744-8069-10-37.


The P2X7 receptor: a key player in immune-mediated bone loss?

Kvist TM, Schwarz P, Jørgensen NR.

ScientificWorldJournal. 2014 Jan 16;2014:954530. doi: 10.1155/2014/954530. eCollection 2014. Review.


The P2X(7) loss-of-function Glu496Ala polymorphism affects ex vivo cytokine release and protects against the cytotoxic effects of high ATP-levels.

Wesselius A, Bours MJ, Arts IC, Theunisz EH, Geusens P, Dagnelie PC.

BMC Immunol. 2012 Dec 4;13:64. doi: 10.1186/1471-2172-13-64.


The specificity protein factor Sp1 mediates transcriptional regulation of P2X7 receptors in the nervous system.

García-Huerta P, Díaz-Hernandez M, Delicado EG, Pimentel-Santillana M, Miras-Portugal MT, Gómez-Villafuertes R.

J Biol Chem. 2012 Dec 28;287(53):44628-44. doi: 10.1074/jbc.M112.390971. Epub 2012 Nov 8.


Non-synonymous polymorphisms in the P2RX ( 4 ) are related to bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients.

Wesselius A, Bours MJ, Jørgensen NR, Wiley J, Gu B, van Helden S, van Rhijn L, Dagnelie PC.

Purinergic Signal. 2013 Mar;9(1):123-30. doi: 10.1007/s11302-012-9337-0. Epub 2012 Nov 10.


Purinergic signalling in bone.

Rumney RM, Wang N, Agrawal A, Gartland A.

Front Endocrinol (Lausanne). 2012 Sep 19;3:116. doi: 10.3389/fendo.2012.00116. eCollection 2012.


P2X7 Receptor Function in Bone-Related Cancer.

Adinolfi E, Amoroso F, Giuliani AL.

J Osteoporos. 2012;2012:637863. doi: 10.1155/2012/637863. Epub 2012 Aug 16.


Modulating P2X7 Receptor Signaling during Rheumatoid Arthritis: New Therapeutic Approaches for Bisphosphonates.

Baroja-Mazo A, Pelegrín P.

J Osteoporos. 2012;2012:408242. doi: 10.1155/2012/408242. Epub 2012 Jul 8.


Association of P2X7 receptor polymorphisms with bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients.

Wesselius A, Bours MJ, Henriksen Z, Syberg S, Petersen S, Schwarz P, Jørgensen NR, van Helden S, Dagnelie PC.

Osteoporos Int. 2013 Apr;24(4):1235-46. doi: 10.1007/s00198-012-2059-x. Epub 2012 Jul 10.


Polymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal women.

Gartland A, Skarratt KK, Hocking LJ, Parsons C, Stokes L, Jørgensen NR, Fraser WD, Reid DM, Gallagher JA, Wiley JS.

Eur J Hum Genet. 2012 May;20(5):559-64. doi: 10.1038/ejhg.2011.245. Epub 2012 Jan 11.

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