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Items: 1 to 20 of 39

1.

Activation of TNFR2 sensitizes macrophages for TNFR1-mediated necroptosis.

Siegmund D, Kums J, Ehrenschwender M, Wajant H.

Cell Death Dis. 2016 Sep 22;7(9):e2375. doi: 10.1038/cddis.2016.285.

2.

Protein aggregation as a cellular response to oxidative stress induced by heme and iron.

Vasconcellos LR, Dutra FF, Siqueira MS, Paula-Neto HA, Dahan J, Kiarely E, Carneiro LA, Bozza MT, Travassos LH.

Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7474-E7482. Epub 2016 Nov 7.

3.

Altered heme-mediated modulation of dendritic cell function in sickle cell alloimmunization.

Godefroy E, Liu Y, Shi P, Mitchell WB, Cohen D, Chou ST, Manwani D, Yazdanbakhsh K.

Haematologica. 2016 Sep;101(9):1028-38. doi: 10.3324/haematol.2016.147181. Epub 2016 May 26.

4.

RIPK1 and PGAM5 Control Leishmania Replication through Distinct Mechanisms.

Farias Luz N, Balaji S, Okuda K, Barreto AS, Bertin J, Gough PJ, Gazzinelli R, Almeida RP, Bozza MT, Borges VM, Chan FK.

J Immunol. 2016 Jun 15;196(12):5056-63. doi: 10.4049/jimmunol.1502492. Epub 2016 May 16.

PMID:
27183605
5.

The Reactive Oxygen Species in Macrophage Polarization: Reflecting Its Dual Role in Progression and Treatment of Human Diseases.

Tan HY, Wang N, Li S, Hong M, Wang X, Feng Y.

Oxid Med Cell Longev. 2016;2016:2795090. doi: 10.1155/2016/2795090. Epub 2016 Apr 6. Review.

6.

Macrophages and Iron Metabolism.

Soares MP, Hamza I.

Immunity. 2016 Mar 15;44(3):492-504. doi: 10.1016/j.immuni.2016.02.016. Review.

7.

Hemoglobinuria-related acute kidney injury is driven by intrarenal oxidative reactions triggering a heme toxicity response.

Deuel JW, Schaer CA, Boretti FS, Opitz L, Garcia-Rubio I, Baek JH, Spahn DR, Buehler PW, Schaer DJ.

Cell Death Dis. 2016 Jan 21;7:e2064. doi: 10.1038/cddis.2015.392.

8.

Hemopexin therapy reverts heme-induced proinflammatory phenotypic switching of macrophages in a mouse model of sickle cell disease.

Vinchi F, Costa da Silva M, Ingoglia G, Petrillo S, Brinkman N, Zuercher A, Cerwenka A, Tolosano E, Muckenthaler MU.

Blood. 2016 Jan 28;127(4):473-86. doi: 10.1182/blood-2015-08-663245. Epub 2015 Dec 16.

9.

Heme-Mediated Induction of CXCL10 and Depletion of CD34+ Progenitor Cells Is Toll-Like Receptor 4 Dependent.

Dickinson-Copeland CM, Wilson NO, Liu M, Driss A, Salifu H, Adjei AA, Wilson M, Gyan B, Oduro D, Badu K, Botchway F, Anderson W, Bond V, Bacanamwo M, Singh S, Stiles JK.

PLoS One. 2015 Nov 10;10(11):e0142328. doi: 10.1371/journal.pone.0142328. eCollection 2015. Erratum in: PLoS One. 2016;11(1):e0147460.

10.

The Iron age of host-microbe interactions.

Soares MP, Weiss G.

EMBO Rep. 2015 Nov;16(11):1482-500. doi: 10.15252/embr.201540558. Epub 2015 Oct 16. Review.

11.

How Heme Oxygenase-1 Prevents Heme-Induced Cell Death.

Lanceta L, Mattingly JM, Li C, Eaton JW.

PLoS One. 2015 Aug 13;10(8):e0134144. doi: 10.1371/journal.pone.0134144. eCollection 2015.

12.

Hemopexin and haptoglobin: allies against heme toxicity from hemoglobin not contenders.

Smith A, McCulloh RJ.

Front Physiol. 2015 Jun 30;6:187. doi: 10.3389/fphys.2015.00187. eCollection 2015. Review.

13.

EP2 Receptor Signaling Regulates Microglia Death.

Fu Y, Yang MS, Jiang J, Ganesh T, Joe E, Dingledine R.

Mol Pharmacol. 2015 Jul;88(1):161-70. doi: 10.1124/mol.115.098202. Epub 2015 Feb 25.

14.

The pathophysiology of extracellular hemoglobin associated with enhanced oxidative reactions.

Rifkind JM, Mohanty JG, Nagababu E.

Front Physiol. 2015 Jan 14;5:500. doi: 10.3389/fphys.2014.00500. eCollection 2014. Review.

15.

Neoalbaconol induces cell death through necroptosis by regulating RIPK-dependent autocrine TNFα and ROS production.

Yu X, Deng Q, Li W, Xiao L, Luo X, Liu X, Yang L, Peng S, Ding Z, Feng T, Zhou J, Fan J, Bode AM, Dong Z, Liu J, Cao Y.

Oncotarget. 2015 Feb 10;6(4):1995-2008.

16.

Role of heme in cardiovascular physiology and disease.

Sawicki KT, Chang HC, Ardehali H.

J Am Heart Assoc. 2015 Jan 5;4(1):e001138. doi: 10.1161/JAHA.114.001138. Review. No abstract available.

17.

Programmed necrosis in the cross talk of cell death and inflammation.

Chan FK, Luz NF, Moriwaki K.

Annu Rev Immunol. 2015;33:79-106. doi: 10.1146/annurev-immunol-032414-112248. Epub 2014 Dec 10. Review.

18.

Haptoglobin, hemopexin, and related defense pathways-basic science, clinical perspectives, and drug development.

Schaer DJ, Vinchi F, Ingoglia G, Tolosano E, Buehler PW.

Front Physiol. 2014 Oct 28;5:415. doi: 10.3389/fphys.2014.00415. eCollection 2014. Review.

19.

Iron, inflammation, and early death in adults with sickle cell disease.

van Beers EJ, Yang Y, Raghavachari N, Tian X, Allen DT, Nichols JS, Mendelsohn L, Nekhai S, Gordeuk VR, Taylor JG 6th, Kato GJ.

Circ Res. 2015 Jan 16;116(2):298-306. doi: 10.1161/CIRCRESAHA.116.304577. Epub 2014 Nov 6.

20.

Proteasome inhibition and oxidative reactions disrupt cellular homeostasis during heme stress.

Vallelian F, Deuel JW, Opitz L, Schaer CA, Puglia M, Lönn M, Engelsberger W, Schauer S, Karnaukhova E, Spahn DR, Stocker R, Buehler PW, Schaer DJ.

Cell Death Differ. 2015 Apr;22(4):597-611. doi: 10.1038/cdd.2014.154. Epub 2014 Oct 10.

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