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Distinct Roles of Wnt/β-Catenin Signaling in the Pathogenesis of Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis.

Shi J, Li F, Luo M, Wei J, Liu X.

Mediators Inflamm. 2017;2017:3520581. doi: 10.1155/2017/3520581. Epub 2017 May 9. Review.


Leptin signals via TGFB1 to promote metastatic potential and stemness in breast cancer.

Mishra AK, Parish CR, Wong ML, Licinio J, Blackburn AC.

PLoS One. 2017 May 25;12(5):e0178454. doi: 10.1371/journal.pone.0178454. eCollection 2017.


Small molecule p300/catenin antagonist enhances hematopoietic recovery after radiation.

Zhao Y, Wu K, Nguyen C, Smbatyan G, Melendez E, Higuchi Y, Chen Y, Kahn M.

PLoS One. 2017 May 9;12(5):e0177245. doi: 10.1371/journal.pone.0177245. eCollection 2017.


Long Non-Coding RNAs: Key Regulators of Epithelial-Mesenchymal Transition, Tumour Drug Resistance and Cancer Stem Cells.

Heery R, Finn SP, Cuffe S, Gray SG.

Cancers (Basel). 2017 Apr 21;9(4). pii: E38. doi: 10.3390/cancers9040038. Review.


Human Lung Spheroids as In Vitro Niches of Lung Progenitor Cells with Distinctive Paracrine and Plasticity Properties.

Chimenti I, Pagano F, Angelini F, Siciliano C, Mangino G, Picchio V, De Falco E, Peruzzi M, Carnevale R, Ibrahim M, Biondi-Zoccai G, Messina E, Frati G.

Stem Cells Transl Med. 2017 Mar;6(3):767-777. doi: 10.5966/sctm.2015-0374. Epub 2016 Sep 22.


Cthrc1 lowers pulmonary collagen associated with bleomycin-induced fibrosis and protects lung function.

Binks AP, Beyer M, Miller R, LeClair RJ.

Physiol Rep. 2017 Mar;5(5). pii: e13115. doi: 10.14814/phy2.13115.


Dibutyryl-cAMP attenuates pulmonary fibrosis by blocking myofibroblast differentiation via PKA/CREB/CBP signaling in rats with silicosis.

Liu Y, Xu H, Geng Y, Xu D, Zhang L, Yang Y, Wei Z, Zhang B, Li S, Gao X, Wang R, Zhang X, Brann D, Yang F.

Respir Res. 2017 Feb 21;18(1):38. doi: 10.1186/s12931-017-0523-z.


Role of glycogen synthase kinase-3β and PPAR-γ on epithelial-to-mesenchymal transition in DSS-induced colorectal fibrosis.

Di Gregorio J, Sferra R, Speca S, Vetuschi A, Dubuquoy C, Desreumaux P, Pompili S, Cristiano L, Gaudio E, Flati V, Latella G.

PLoS One. 2017 Feb 16;12(2):e0171093. doi: 10.1371/journal.pone.0171093. eCollection 2017.


Regulation of miRNA-29c and its downstream pathways in preneoplastic progression of triple-negative breast cancer.

Bhardwaj A, Singh H, Rajapakshe K, Tachibana K, Ganesan N, Pan Y, Gunaratne PH, Coarfa C, Bedrosian I.

Oncotarget. 2017 Mar 21;8(12):19645-19660. doi: 10.18632/oncotarget.14902.


The pattern of hMENA isoforms is regulated by TGF-β1 in pancreatic cancer and may predict patient outcome.

Melchionna R, Iapicca P, Di Modugno F, Trono P, Sperduti I, Fassan M, Cataldo I, Rusev BC, Lawlor RT, Diodoro MG, Milella M, Grazi GL, Bissell MJ, Scarpa A, Nisticò P.

Oncoimmunology. 2016 Aug 12;5(12):e1221556. doi: 10.1080/2162402X.2016.1221556. eCollection 2016.


Signaling Crosstalk between Tubular Epithelial Cells and Interstitial Fibroblasts after Kidney Injury.

Tan RJ, Zhou D, Liu Y.

Kidney Dis (Basel). 2016 Oct;2(3):136-144. Epub 2016 May 21. Review.


Examining Crosstalk among Transforming Growth Factor β, Bone Morphogenetic Protein, and Wnt Pathways.

Coster AD, Thorne CA, Wu LF, Altschuler SJ.

J Biol Chem. 2017 Jan 6;292(1):244-250. doi: 10.1074/jbc.M116.759654. Epub 2016 Nov 28.


The Aryl Hydrocarbon Receptor and Its Ligands Inhibit Myofibroblast Formation and Activation: Implications for Thyroid Eye Disease.

Woeller CF, Roztocil E, Hammond CL, Feldon SE, Phipps RP.

Am J Pathol. 2016 Dec;186(12):3189-3202. doi: 10.1016/j.ajpath.2016.08.017. Epub 2016 Nov 11.


β-Catenin/CBP-Dependent Signaling Regulates TGF-β-Induced Epithelial to Mesenchymal Transition of Lens Epithelial Cells.

Taiyab A, Korol A, Deschamps PA, West-Mays JA.

Invest Ophthalmol Vis Sci. 2016 Oct 1;57(13):5736-5747. doi: 10.1167/iovs.16-20162.


Role of BCL9L in transforming growth factor-β (TGF-β)-induced epithelial-to-mesenchymal-transition (EMT) and metastasis of pancreatic cancer.

Sannino G, Armbruster N, Bodenhöfer M, Haerle U, Behrens D, Buchholz M, Rothbauer U, Sipos B, Schmees C.

Oncotarget. 2016 Nov 8;7(45):73725-73738. doi: 10.18632/oncotarget.12455.


Lrp5/β-Catenin Signaling Controls Lung Macrophage Differentiation and Inhibits Resolution of Fibrosis.

Sennello JA, Misharin AV, Flozak AS, Berdnikovs S, Cheresh P, Varga J, Kamp DW, Budinger GR, Gottardi CJ, Lam AP.

Am J Respir Cell Mol Biol. 2017 Feb;56(2):191-201. doi: 10.1165/rcmb.2016-0147OC.


Epigenetic regulation of epithelial-mesenchymal transition.

Sun L, Fang J.

Cell Mol Life Sci. 2016 Dec;73(23):4493-4515. Epub 2016 Jul 8. Review.


Mechanisms of TGFβ-Induced Epithelial-Mesenchymal Transition.

Moustakas A, Heldin CH.

J Clin Med. 2016 Jun 29;5(7). pii: E63. doi: 10.3390/jcm5070063. Review.


Grainyhead-like 2 inhibits the coactivator p300, suppressing tubulogenesis and the epithelial-mesenchymal transition.

Pifer PM, Farris JC, Thomas AL, Stoilov P, Denvir J, Smith DM, Frisch SM.

Mol Biol Cell. 2016 Aug 1;27(15):2479-92. doi: 10.1091/mbc.E16-04-0249. Epub 2016 Jun 1.


Inhibition of Wnt/β-catenin signaling suppresses bleomycin-induced pulmonary fibrosis by attenuating the expression of TGF-β1 and FGF-2.

Chen X, Shi C, Meng X, Zhang K, Li X, Wang C, Xiang Z, Hu K, Han X.

Exp Mol Pathol. 2016 Aug;101(1):22-30. doi: 10.1016/j.yexmp.2016.04.003. Epub 2016 Apr 23.


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