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Iron accelerates hemoglobin oxidation increasing mortality in vascular diseased guinea pigs following transfusion of stored blood.

Baek JH, Yalamanoglu A, Gao Y, Guenster R, Spahn DR, Schaer DJ, Buehler PW.

JCI Insight. 2017 May 4;2(9). pii: 93577. doi: 10.1172/jci.insight.93577. [Epub ahead of print]


Heme as a Target for Therapeutic Interventions.

Immenschuh S, Vijayan V, Janciauskiene S, Gueler F.

Front Pharmacol. 2017 Apr 4;8:146. doi: 10.3389/fphar.2017.00146. eCollection 2017. Review.


Red blood cell components: time to revisit the sources of variability.

Sparrow RL.

Blood Transfus. 2017 Mar;15(2):116-125. doi: 10.2450/2017.0326-16. Review.


The red cell storage lesion(s): of dogs and men.

Klein HG.

Blood Transfus. 2017 Mar;15(2):107-111. doi: 10.2450/2017.0306-16. Review.


Storage of Red Blood Cells and Transfusion-Related Acute Lung Injury.

Babaev A, Pozzi F, Hare G, Zhang H.

J Anesth Crit Care. 2014 Jan 1;1(1). pii: 00002. doi: 10.15406/jaccoa.2014.01.00002.


The impact of red blood cell storage duration on tissue oxygenation in cardiac surgery.

Stowell CP, Whitman G, Granger S, Gomez H, Assmann SF, Massey MJ, Shapiro NI, Steiner ME, Bennett-Guerrero E.

J Thorac Cardiovasc Surg. 2017 Mar;153(3):610-619.e2. doi: 10.1016/j.jtcvs.2016.11.029. Epub 2016 Nov 19.


Quantification of Cell-Free DNA in Red Blood Cell Units in Different Whole Blood Processing Methods.

Shih AW, Bhagirath VC, Heddle NM, Acker JP, Liu Y, Eikelboom JW, Liaw PC.

J Blood Transfus. 2016;2016:9316385. Epub 2016 Sep 27.


Perspectives on the impact of storage duration on blood quality and transfusion outcomes.

Roback JD.

Vox Sang. 2016 Nov;111(4):357-364. doi: 10.1111/vox.12441. Epub 2016 Aug 23.


Exposure of Stored Packed Erythrocytes to Nitric Oxide Prevents Transfusion-associated Pulmonary Hypertension.

Muenster S, Beloiartsev A, Yu B, Du E, Abidi S, Dao M, Fabry G, Graw JA, Wepler M, Malhotra R, Fernandez BO, Feelisch M, Bloch KD, Bloch DB, Zapol WM.

Anesthesiology. 2016 Nov;125(5):952-963.


A Comparative Study of the Effect of Leukoreduction and Pre-storage Leukodepletion on Red Blood Cells during Storage.

Pertinhez TA, Casali E, Baroni F, Berni P, Baricchi R, Spisni A.

Front Mol Biosci. 2016 Apr 21;3:13. doi: 10.3389/fmolb.2016.00013. eCollection 2016.


2,3-Diphosphoglycerate Concentrations in Autologous Salvaged Versus Stored Red Blood Cells and in Surgical Patients After Transfusion.

Scott AV, Nagababu E, Johnson DJ, Kebaish KM, Lipsitz JA, Dwyer IM, Zuckerberg GS, Barodka VM, Berkowitz DE, Frank SM.

Anesth Analg. 2016 Mar;122(3):616-23. doi: 10.1213/ANE.0000000000001071.


Transfusion of recently donated (fresh) red blood cells (RBCs) does not improve survival in comparison with current practice, while safety of the oldest stored units is yet to be established: a meta-analysis.

Remy KE, Sun J, Wang D, Welsh J, Solomon SB, Klein HG, Natanson C, Cortés-Puch I.

Vox Sang. 2016 Jul;111(1):43-54. doi: 10.1111/vox.12380. Epub 2016 Feb 5.


In a canine pneumonia model of exchange transfusion, altering the age but not the volume of older red blood cells markedly alters outcome.

Cortés-Puch I, Remy KE, Solomon SB, Sun J, Wang D, Al-Hamad M, Kelly SM, Sinchar D, Bellavia L, Kanias T, Popovsky MA, Kim-Shapiro DB, Klein HG, Natanson C.

Transfusion. 2015 Nov;55(11):2564-75. doi: 10.1111/trf.13275. Epub 2015 Sep 7.


Impact of the age of stored blood on trauma patient mortality: a systematic review.

Sowers N, Froese PC, Erdogan M, Green RS.

Can J Surg. 2015 Oct;58(5):335-42. Review.


Red blood cell transfusion-induced inflammation: myth or reality.

Hod EA.

ISBT Sci Ser. 2015 Apr;10(Suppl 1):188-191.


Perioperative Red Blood Cell Transfusion: What We Do Not Know.

Lei C, Xiong LZ.

Chin Med J (Engl). 2015 Sep 5;128(17):2383-6. doi: 10.4103/0366-6999.163384. Review.


Effects of Aged Stored Autologous Red Blood Cells on Human Endothelial Function.

Risbano MG, Kanias T, Triulzi D, Donadee C, Barge S, Badlam J, Jain S, Belanger AM, Kim-Shapiro DB, Gladwin MT.

Am J Respir Crit Care Med. 2015 Nov 15;192(10):1223-33. doi: 10.1164/rccm.201501-0145OC.


Red blood cell transfusion is associated with increased hemolysis and an acute phase response in a subset of critically ill children.

L'Acqua C, Bandyopadhyay S, Francis RO, McMahon DJ, Nellis M, Sheth S, Kernie SG, Brittenham GM, Spitalnik SL, Hod EA.

Am J Hematol. 2015 Oct;90(10):915-20. doi: 10.1002/ajh.24119.


Transfused older stored red blood cells improve the clinical course and outcome in a canine lethal hemorrhage and reperfusion model.

Solomon SB, Cortés-Puch I, Sun J, Remy KE, Wang D, Feng J, Khan SS, Sinchar D, Kim-Shapiro DB, Klein HG, Natanson C.

Transfusion. 2015 Nov;55(11):2552-63. doi: 10.1111/trf.13213. Epub 2015 Jul 15.

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