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Single-Cell and Single-Molecule Analysis of Gene Expression Regulation.

Vera M, Biswas J, Senecal A, Singer RH, Park HY.

Annu Rev Genet. 2016 Nov 23;50:267-291.


Msi RNA-binding proteins control reserve intestinal stem cell quiescence.

Yousefi M, Li N, Nakauka-Ddamba A, Wang S, Davidow K, Schoenberger J, Yu Z, Jensen ST, Kharas MG, Lengner CJ.

J Cell Biol. 2016 Nov 7;215(3):401-413.


The Evolution of Per-cell Organelle Number.

Cole LW.

Front Cell Dev Biol. 2016 Aug 18;4:85. doi: 10.3389/fcell.2016.00085. Review.


Wnt pathway regulation of intestinal stem cells.

Mah AT, Yan KS, Kuo CJ.

J Physiol. 2016 Sep 1;594(17):4837-47. doi: 10.1113/JP271754.


Mouse Label-Retaining Cells Are Molecularly and Functionally Distinct From Reserve Intestinal Stem Cells.

Li N, Nakauka-Ddamba A, Tobias J, Jensen ST, Lengner CJ.

Gastroenterology. 2016 Aug;151(2):298-310.e7. doi: 10.1053/j.gastro.2016.04.049.


Notch signalling regulates asymmetric division and inter-conversion between lgr5 and bmi1 expressing intestinal stem cells.

Srinivasan T, Than EB, Bu P, Tung KL, Chen KY, Augenlicht L, Lipkin SM, Shen X.

Sci Rep. 2016 May 16;6:26069. doi: 10.1038/srep26069.


An enduring role for quiescent stem cells.

Richmond CA, Shah MS, Carlone DL, Breault DT.

Dev Dyn. 2016 Jul;245(7):718-26. doi: 10.1002/dvdy.24416.


Stem cell dynamics and pretumor progression in the intestinal tract.

Ma H, Morsink FH, Offerhaus GJ, de Leng WW.

J Gastroenterol. 2016 Sep;51(9):841-52. doi: 10.1007/s00535-016-1211-3. Review.


The regulatory niche of intestinal stem cells.

Sailaja BS, He XC, Li L.

J Physiol. 2016 Sep 1;594(17):4827-36. doi: 10.1113/JP271931.


The Genetic Program of Pancreatic β-Cell Replication In Vivo.

Klochendler A, Caspi I, Corem N, Moran M, Friedlich O, Elgavish S, Nevo Y, Helman A, Glaser B, Eden A, Itzkovitz S, Dor Y.

Diabetes. 2016 Jul;65(7):2081-93. doi: 10.2337/db16-0003.


Nuclear Retention of mRNA in Mammalian Tissues.

Bahar Halpern K, Caspi I, Lemze D, Levy M, Landen S, Elinav E, Ulitsky I, Itzkovitz S.

Cell Rep. 2015 Dec 29;13(12):2653-62. doi: 10.1016/j.celrep.2015.11.036.


Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis.

Rabinovich S, Adler L, Yizhak K, Sarver A, Silberman A, Agron S, Stettner N, Sun Q, Brandis A, Helbling D, Korman S, Itzkovitz S, Dimmock D, Ulitsky I, Nagamani SC, Ruppin E, Erez A.

Nature. 2015 Nov 19;527(7578):379-83. doi: 10.1038/nature15529.


Cytometry-based single-cell analysis of intact epithelial signaling reveals MAPK activation divergent from TNF-α-induced apoptosis in vivo.

Simmons AJ, Banerjee A, McKinley ET, Scurrah CR, Herring CA, Gewin LS, Masuzaki R, Karp SJ, Franklin JL, Gerdes MJ, Irish JM, Coffey RJ, Lau KS.

Mol Syst Biol. 2015 Oct 30;11(10):835. doi: 10.15252/msb.20156282. Erratum in: Mol Syst Biol. 2016;12(8):881.


Distinct Processes and Transcriptional Targets Underlie CDX2 Requirements in Intestinal Stem Cells and Differentiated Villus Cells.

San Roman AK, Tovaglieri A, Breault DT, Shivdasani RA.

Stem Cell Reports. 2015 Nov 10;5(5):673-81. doi: 10.1016/j.stemcr.2015.09.006.


Dclk1+ small intestinal epithelial tuft cells display the hallmarks of quiescence and self-renewal.

Chandrakesan P, May R, Qu D, Weygant N, Taylor VE, Li JD, Ali N, Sureban SM, Qante M, Wang TC, Bronze MS, Houchen CW.

Oncotarget. 2015 Oct 13;6(31):30876-86. doi: 10.18632/oncotarget.5129.


A Mouse Model of Targeted Musashi1 Expression in Whole Intestinal Epithelium Suggests Regulatory Roles in Cell Cycle and Stemness.

Cambuli FM, Correa BR, Rezza A, Burns SC, Qiao M, Uren PJ, Kress E, Boussouar A, Galante PA, Penalva LO, Plateroti M.

Stem Cells. 2015 Dec;33(12):3621-34. doi: 10.1002/stem.2202.


Novel regenerative peptide TP508 mitigates radiation-induced gastrointestinal damage by activating stem cells and preserving crypt integrity.

Kantara C, Moya SM, Houchen CW, Umar S, Ullrich RL, Singh P, Carney DH.

Lab Invest. 2015 Nov;95(11):1222-33. doi: 10.1038/labinvest.2015.103.


Mutant p53 accumulates in cycling and proliferating cells in the normal tissues of p53 R172H mutant mice.

Goh AM, Xue Y, Leushacke M, Li L, Wong JS, Chiam PC, Rahmat SA, Mann MB, Mann KM, Barker N, Lozano G, Terzian T, Lane DP.

Oncotarget. 2015 Jul 20;6(20):17968-80.


Multiscale analysis of the murine intestine for modeling human diseases.

Lyons J, Herring CA, Banerjee A, Simmons AJ, Lau KS.

Integr Biol (Camb). 2015 Jul;7(7):740-57. doi: 10.1039/c5ib00030k.


Microenvironmental control of stem cell fate in intestinal homeostasis and disease.

Biswas S, Davis H, Irshad S, Sandberg T, Worthley D, Leedham S.

J Pathol. 2015 Oct;237(2):135-45. doi: 10.1002/path.4563. Review.

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