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Items: 1 to 20 of 198


Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma.

Mario Gonzalez-Meljem J, Haston S, Carreno G, Apps JR, Pozzi S, Stache C, Kaushal G, Virasami A, Panousopoulos L, Neda Mousavy-Gharavy S, Guerrero A, Rashid M, Jani N, Goding CR, Jacques TS, Adams DJ, Gil J, Andoniadou CL, Pedro Martinez-Barbera J.

Nat Commun. 2017 Nov 28;8(1):1819. doi: 10.1038/s41467-017-01992-5.


Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors.

Saunderson EA, Stepper P, Gomm JJ, Hoa L, Morgan A, Allen MD, Jones JL, Gribben JG, Jurkowski TP, Ficz G.

Nat Commun. 2017 Nov 13;8(1):1450. doi: 10.1038/s41467-017-01078-2.


Regenerative Medicine: Shedding Light on the Link between Aging and Cancer.

Marongiu F, Serra MP, Fanti M, Cadoni E, Serra M, Laconi E.

Cell Transplant. 2017 Sep;26(9):1530-1537. doi: 10.1177/0963689717721224.


Cancer vaccines and immunotherapeutic approaches in hepatobiliary and pancreatic cancers.

Hochnadel I, Kossatz-Boehlert U, Jedicke N, Lenzen H, Manns MP, Yevsa T.

Hum Vaccin Immunother. 2017 Dec 2;13(12):2931-2952. doi: 10.1080/21645515.2017.1359362. Epub 2017 Nov 7.


Cancer and Aging - the Inflammatory Connection.

Zinger A, Cho WC, Ben-Yehuda A.

Aging Dis. 2017 Oct 1;8(5):611-627. doi: 10.14336/AD.2016.1230. eCollection 2017 Oct. Review.


The potential of targeting Sin3B and its associated complexes for cancer therapy.

Cantor DJ, David G.

Expert Opin Ther Targets. 2017 Nov;21(11):1051-1061. doi: 10.1080/14728222.2017.1386655. Epub 2017 Oct 9. Review.


Differential Serum Cytokine Profiles in Patients with Chronic Hepatitis B, C, and Hepatocellular Carcinoma.

Estevez J, Chen VL, Podlaha O, Li B, Le A, Vutien P, Chang ET, Rosenberg-Hasson Y, Jiang Z, Pflanz S, Ge D, Gaggar A, Nguyen MH.

Sci Rep. 2017 Sep 19;7(1):11867. doi: 10.1038/s41598-017-11975-7.


The Potential Role of Senescence As a Modulator of Platelets and Tumorigenesis.

Valenzuela CA, Quintanilla R, Moore-Carrasco R, Brown NE.

Front Oncol. 2017 Aug 28;7:188. doi: 10.3389/fonc.2017.00188. eCollection 2017.


Downregulation of endometrial mesenchymal marker SUSD2 causes cell senescence and cell death in endometrial carcinoma cells.

Zhang S, Zeng N, Alowayed N, Singh Y, Cheng A, Lang F, Salker MS.

PLoS One. 2017 Aug 25;12(8):e0183681. doi: 10.1371/journal.pone.0183681. eCollection 2017.


FOXQ1 regulates senescence-associated inflammation via activation of SIRT1 expression.

Wang P, Lv C, Zhang T, Liu J, Yang J, Guan F, Hong T.

Cell Death Dis. 2017 Jul 20;8(7):e2946. doi: 10.1038/cddis.2017.340.


Macrophages in age-related chronic inflammatory diseases.

Oishi Y, Manabe I.

NPJ Aging Mech Dis. 2016 Jul 28;2:16018. doi: 10.1038/npjamd.2016.18. eCollection 2016. Review.


YAP determines the cell fate of injured mouse hepatocytes in vivo.

Miyamura N, Hata S, Itoh T, Tanaka M, Nishio M, Itoh M, Ogawa Y, Terai S, Sakaida I, Suzuki A, Miyajima A, Nishina H.

Nat Commun. 2017 Jul 6;8:16017. doi: 10.1038/ncomms16017. Erratum in: Nat Commun. 2017 Aug 07;8:16146.


Amplification of N-Myc is associated with a T-cell-poor microenvironment in metastatic neuroblastoma restraining interferon pathway activity and chemokine expression.

Layer JP, Kronmüller MT, Quast T, van den Boorn-Konijnenberg D, Effern M, Hinze D, Althoff K, Schramm A, Westermann F, Peifer M, Hartmann G, Tüting T, Kolanus W, Fischer M, Schulte J, Hölzel M.

Oncoimmunology. 2017 Apr 28;6(6):e1320626. doi: 10.1080/2162402X.2017.1320626. eCollection 2017.


Oncogene-Expressing Senescent Melanocytes Up-Regulate MHC Class II, a Candidate Melanoma Suppressor Function.

van Tuyn J, Jaber-Hijazi F, MacKenzie D, Cole JJ, Mann E, Pawlikowski JS, Rai TS, Nelson DM, McBryan T, Ivanov A, Blyth K, Wu H, Milling S, Adams PD.

J Invest Dermatol. 2017 Oct;137(10):2197-2207. doi: 10.1016/j.jid.2017.05.030. Epub 2017 Jun 22.


Cellular senescence drives age-dependent hepatic steatosis.

Ogrodnik M, Miwa S, Tchkonia T, Tiniakos D, Wilson CL, Lahat A, Day CP, Burt A, Palmer A, Anstee QM, Grellscheid SN, Hoeijmakers JHJ, Barnhoorn S, Mann DA, Bird TG, Vermeij WP, Kirkland JL, Passos JF, von Zglinicki T, Jurk D.

Nat Commun. 2017 Jun 13;8:15691. doi: 10.1038/ncomms15691.


Senescence in Health and Disease.

He S, Sharpless NE.

Cell. 2017 Jun 1;169(6):1000-1011. doi: 10.1016/j.cell.2017.05.015. Review.


CXCL13-producing TFH cells link immune suppression and adaptive memory in human breast cancer.

Gu-Trantien C, Migliori E, Buisseret L, de Wind A, Brohée S, Garaud S, Noël G, Dang Chi VL, Lodewyckx JN, Naveaux C, Duvillier H, Goriely S, Larsimont D, Willard-Gallo K.

JCI Insight. 2017 Jun 2;2(11). pii: 91487. doi: 10.1172/jci.insight.91487. [Epub ahead of print]


CRISPR/Cas9-based Pten knock-out and Sleeping Beauty Transposon-mediated Nras knock-in induces hepatocellular carcinoma and hepatic lipid accumulation in mice.

Gao M, Liu D.

Cancer Biol Ther. 2017 Jul 3;18(7):505-512. doi: 10.1080/15384047.2017.1323597. Epub 2017 May 17.


A Novel Indication for Panobinostat as a Senolytic Drug in NSCLC and HNSCC.

Samaraweera L, Adomako A, Rodriguez-Gabin A, McDaid HM.

Sci Rep. 2017 May 15;7(1):1900. doi: 10.1038/s41598-017-01964-1.


SASP regulation by noncoding RNA.

Panda AC, Abdelmohsen K, Gorospe M.

Mech Ageing Dev. 2017 May 11. pii: S0047-6374(16)30298-6. doi: 10.1016/j.mad.2017.05.004. [Epub ahead of print] Review.


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