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Items: 1 to 20 of 48

1.
2.

NPTX2 and cognitive dysfunction in Alzheimer's Disease.

Xiao MF, Xu D, Craig MT, Pelkey KA, Chien CC, Shi Y, Zhang J, Resnick S, Pletnikova O, Salmon D, Brewer J, Edland S, Wegiel J, Tycko B, Savonenko A, Reeves RH, Troncoso JC, McBain CJ, Galasko D, Worley PF.

Elife. 2017 Mar 23;6. pii: e23798. doi: 10.7554/eLife.23798.

3.

Regulation of Synaptic Amyloid-β Generation through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease.

Ye X, Feng T, Tammineni P, Chang Q, Jeong YY, Margolis DJ, Cai H, Kusnecov A, Cai Q.

J Neurosci. 2017 Mar 8;37(10):2639-2655. doi: 10.1523/JNEUROSCI.2851-16.2017. Epub 2017 Feb 3.

PMID:
28159908
4.

Autophagy-mediated Regulation of BACE1 Protein Trafficking and Degradation.

Feng T, Tammineni P, Agrawal C, Jeong YY, Cai Q.

J Biol Chem. 2017 Feb 3;292(5):1679-1690. doi: 10.1074/jbc.M116.766584. Epub 2016 Dec 27.

PMID:
28028177
5.

TRIAD3/RNF216 mutations associated with Gordon Holmes syndrome lead to synaptic and cognitive impairments via Arc misregulation.

Husain N, Yuan Q, Yen YC, Pletnikova O, Sally DQ, Worley P, Bichler Z, Shawn Je H.

Aging Cell. 2017 Apr;16(2):281-292. doi: 10.1111/acel.12551. Epub 2016 Dec 20.

6.

Activity-dependent proteolytic cleavage of cell adhesion molecules regulates excitatory synaptic development and function.

Nagappan-Chettiar S, Johnson-Venkatesh EM, Umemori H.

Neurosci Res. 2017 Mar;116:60-69. doi: 10.1016/j.neures.2016.12.003. Epub 2016 Dec 10. Review.

PMID:
27965136
7.

Amyloid-β-Induced Dysregulation of AMPA Receptor Trafficking.

Guntupalli S, Widagdo J, Anggono V.

Neural Plast. 2016;2016:3204519. doi: 10.1155/2016/3204519. Epub 2016 Mar 17. Review.

8.

Super-resolution microscopy reveals γ-secretase at both sides of the neuronal synapse.

Schedin-Weiss S, Caesar I, Winblad B, Blom H, Tjernberg LO.

Acta Neuropathol Commun. 2016 Mar 31;4:29. doi: 10.1186/s40478-016-0296-5.

9.

Emerging Link between Alzheimer's Disease and Homeostatic Synaptic Plasticity.

Jang SS, Chung HJ.

Neural Plast. 2016;2016:7969272. doi: 10.1155/2016/7969272. Epub 2016 Feb 25. Review.

10.

Inter-Dependent Mechanisms Behind Cognitive Dysfunction, Vascular Biology and Alzheimer's Dementia in Down Syndrome: Multi-Faceted Roles of APP.

Nizetic D, Chen CL, Hong W, Koo EH.

Front Behav Neurosci. 2015 Dec 1;9:299. doi: 10.3389/fnbeh.2015.00299. eCollection 2015.

11.

Common variants in the ARC gene are not associated with cognitive abilities.

Myrum C, Giddaluru S, Jacobsen K, Espeseth T, Nyberg L, Lundervold AJ, Haavik J, Nilsson LG, Reinvang I, Steen VM, Johansson S, Wibrand K, Le Hellard S, Bramham CR.

Brain Behav. 2015 Sep 3;5(10):e00376. doi: 10.1002/brb3.376. eCollection 2015 Oct.

12.

Nuclear Arc Interacts with the Histone Acetyltransferase Tip60 to Modify H4K12 Acetylation(1,2,3).

Wee CL, Teo S, Oey NE, Wright GD, VanDongen HM, VanDongen AM.

eNeuro. 2014 Nov 12;1(1). pii: ENEURO.0019-14.2014. doi: 10.1523/ENEURO.0019-14.2014. eCollection 2014 Nov-Dec.

13.

The endosomal-lysosomal system: from acidification and cargo sorting to neurodegeneration.

Hu YB, Dammer EB, Ren RJ, Wang G.

Transl Neurodegener. 2015 Sep 30;4:18. doi: 10.1186/s40035-015-0041-1. eCollection 2015. Review.

14.

Genetic Modifiers of Age at Onset in Carriers of the G206A Mutation in PSEN1 With Familial Alzheimer Disease Among Caribbean Hispanics.

Lee JH, Cheng R, Vardarajan B, Lantigua R, Reyes-Dumeyer D, Ortmann W, Graham RR, Bhangale T, Behrens TW, Medrano M, Jiménez-Velázquez IZ, Mayeux R.

JAMA Neurol. 2015 Sep;72(9):1043-51. doi: 10.1001/jamaneurol.2015.1424.

15.

Cdk5 is a New Rapid Synaptic Homeostasis Regulator Capable of Initiating the Early Alzheimer-Like Pathology.

Sheng Y, Zhang L, Su SC, Tsai LH, Julius Zhu J.

Cereb Cortex. 2016 Jul;26(7):2937-51. doi: 10.1093/cercor/bhv032. Epub 2015 Jun 17.

PMID:
26088971
16.

Transgene expression in the Nop-tTA driver line is not inherently restricted to the entorhinal cortex.

Yetman MJ, Lillehaug S, Bjaalie JG, Leergaard TB, Jankowsky JL.

Brain Struct Funct. 2016 May;221(4):2231-49. doi: 10.1007/s00429-015-1040-9. Epub 2015 Apr 14.

17.

Structural basis of arc binding to synaptic proteins: implications for cognitive disease.

Zhang W, Wu J, Ward MD, Yang S, Chuang YA, Xiao M, Li R, Leahy DJ, Worley PF.

Neuron. 2015 Apr 22;86(2):490-500. doi: 10.1016/j.neuron.2015.03.030. Epub 2015 Apr 9.

18.

Arc is a flexible modular protein capable of reversible self-oligomerization.

Myrum C, Baumann A, Bustad HJ, Flydal MI, Mariaule V, Alvira S, Cuéllar J, Haavik J, Soulé J, Valpuesta JM, Márquez JA, Martinez A, Bramham CR.

Biochem J. 2015 May 15;468(1):145-58. doi: 10.1042/BJ20141446.

19.

Complex regulation of γ-secretase: from obligatory to modulatory subunits.

Gertsik N, Chiu D, Li YM.

Front Aging Neurosci. 2015 Jan 6;6:342. doi: 10.3389/fnagi.2014.00342. eCollection 2014. Review.

20.

The Na+/H+ exchanger NHE6 modulates endosomal pH to control processing of amyloid precursor protein in a cell culture model of Alzheimer disease.

Prasad H, Rao R.

J Biol Chem. 2015 Feb 27;290(9):5311-27. doi: 10.1074/jbc.M114.602219. Epub 2015 Jan 5.

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