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Items: 1 to 20 of 132

1.

Intestinal, but not hepatic, ChREBP is required for fructose tolerance.

Kim M, Astapova II, Flier SN, Hannou SA, Doridot L, Sargsyan A, Kou HH, Fowler AJ, Liang G, Herman MA.

JCI Insight. 2017 Dec 21;2(24). pii: 96703. doi: 10.1172/jci.insight.96703. [Epub ahead of print]

2.

PLATO software provides analytic framework for investigating complexity beyond genome-wide association studies.

Hall MA, Wallace J, Lucas A, Kim D, Basile AO, Verma SS, McCarty CA, Brilliant MH, Peissig PL, Kitchner TE, Verma A, Pendergrass SA, Dudek SM, Moore JH, Ritchie MD.

Nat Commun. 2017 Oct 27;8(1):1167. doi: 10.1038/s41467-017-00802-2.

3.

Δ-5 Fatty Acid Desaturase FADS1 Impacts Metabolic Disease by Balancing Proinflammatory and Proresolving Lipid Mediators.

Gromovsky AD, Schugar RC, Brown AL, Helsley RN, Burrows AC, Ferguson D, Zhang R, Sansbury BE, Lee RG, Morton RE, Allende DS, Parks JS, Spite M, Brown JM.

Arterioscler Thromb Vasc Biol. 2018 Jan;38(1):218-231. doi: 10.1161/ATVBAHA.117.309660. Epub 2017 Oct 26.

PMID:
29074585
4.

Precision Nutrition and Omega-3 Polyunsaturated Fatty Acids: A Case for Personalized Supplementation Approaches for the Prevention and Management of Human Diseases.

Chilton FH, Dutta R, Reynolds LM, Sergeant S, Mathias RA, Seeds MC.

Nutrients. 2017 Oct 25;9(11). pii: E1165. doi: 10.3390/nu9111165. Review.

5.

JMJD1C Ensures Mouse Embryonic Stem Cell Self-Renewal and Somatic Cell Reprogramming through Controlling MicroRNA Expression.

Xiao F, Liao B, Hu J, Li S, Zhao H, Sun M, Gu J, Jin Y.

Stem Cell Reports. 2017 Sep 12;9(3):927-942. doi: 10.1016/j.stemcr.2017.07.013. Epub 2017 Aug 17.

6.

The SNP-set based association study identifies ITGA1 as a susceptibility gene of attention-deficit/hyperactivity disorder in Han Chinese.

Liu L, Zhang L, Li HM, Wang ZR, Xie XF, Mei JP, Jin JL, Shi J, Sun L, Li SC, Tan YL, Yang L, Wang J, Yang HM, Qian QJ, Wang YF.

Transl Psychiatry. 2017 Aug 15;7(8):e1201. doi: 10.1038/tp.2017.156.

7.

Rare coding variants pinpoint genes that control human hematological traits.

Mousas A, Ntritsos G, Chen MH, Song C, Huffman JE, Tzoulaki I, Elliott P, Psaty BM; Blood-Cell Consortium, Auer PL, Johnson AD, Evangelou E, Lettre G, Reiner AP.

PLoS Genet. 2017 Aug 7;13(8):e1006925. doi: 10.1371/journal.pgen.1006925. eCollection 2017 Aug.

8.

Population and allelic variation of A-to-I RNA editing in human transcriptomes.

Park E, Guo J, Shen S, Demirdjian L, Wu YN, Lin L, Xing Y.

Genome Biol. 2017 Jul 28;18(1):143. doi: 10.1186/s13059-017-1270-7.

9.

Clinical Applicability of Whole-Exome Sequencing Exemplified by a Study in Young Adults with the Advanced Cryptogenic Cholestatic Liver Diseases.

Kulecka M, Habior A, Paziewska A, Goryca K, Dąbrowska M, Ambrozkiewicz F, Walewska-Zielecka B, Gabriel A, Mikula M, Ostrowski J.

Gastroenterol Res Pract. 2017;2017:4761962. doi: 10.1155/2017/4761962. Epub 2017 May 24.

10.

EphA2 Expression Regulates Inflammation and Fibroproliferative Remodeling in Atherosclerosis.

Finney AC, Funk SD, Green JM, Yurdagul A Jr, Rana MA, Pistorius R, Henry M, Yurochko A, Pattillo CB, Traylor JG, Chen J, Woolard MD, Kevil CG, Orr AW.

Circulation. 2017 Aug 8;136(6):566-582. doi: 10.1161/CIRCULATIONAHA.116.026644. Epub 2017 May 9.

PMID:
28487392
11.

Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci.

Stender S, Kozlitina J, Nordestgaard BG, Tybjærg-Hansen A, Hobbs HH, Cohen JC.

Nat Genet. 2017 Jun;49(6):842-847. doi: 10.1038/ng.3855. Epub 2017 Apr 24.

12.

Missing heritability: is the gap closing? An analysis of 32 complex traits in the Lifelines Cohort Study.

Nolte IM, van der Most PJ, Alizadeh BZ, de Bakker PI, Boezen HM, Bruinenberg M, Franke L, van der Harst P, Navis G, Postma DS, Rots MG, Stolk RP, Swertz MA, Wolffenbuttel BH, Wijmenga C, Snieder H.

Eur J Hum Genet. 2017 Jun;25(7):877-885. doi: 10.1038/ejhg.2017.50. Epub 2017 Apr 12.

PMID:
28401901
13.

The impact of structural variation on human gene expression.

Chiang C, Scott AJ, Davis JR, Tsang EK, Li X, Kim Y, Hadzic T, Damani FN, Ganel L; GTEx Consortium, Montgomery SB, Battle A, Conrad DF, Hall IM.

Nat Genet. 2017 May;49(5):692-699. doi: 10.1038/ng.3834. Epub 2017 Apr 3.

14.

Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits.

Grassmann F, Kiel C, Zimmermann ME, Gorski M, Grassmann V, Stark K; International AMD Genomics Consortium (IAMDGC), Heid IM, Weber BH.

Genome Med. 2017 Mar 27;9(1):29. doi: 10.1186/s13073-017-0418-0.

15.

Genetic predisposition in nonalcoholic fatty liver disease.

Sookoian S, Pirola CJ.

Clin Mol Hepatol. 2017 Mar;23(1):1-12. doi: 10.3350/cmh.2016.0109. Epub 2017 Mar 9. Review.

16.

A powerful statistical framework for generalization testing in GWAS, with application to the HCHS/SOL.

Sofer T, Heller R, Bogomolov M, Avery CL, Graff M, North KE, Reiner AP, Thornton TA, Rice K, Benjamini Y, Laurie CC, Kerr KF.

Genet Epidemiol. 2017 Apr;41(3):251-258. doi: 10.1002/gepi.22029. Epub 2017 Jan 15.

PMID:
28090672
17.

Genome-Wide Study Links PNPLA3 Variant With Elevated Hepatic Transaminase After Acute Lymphoblastic Leukemia Therapy.

Liu Y, Fernandez CA, Smith C, Yang W, Cheng C, Panetta JC, Kornegay N, Liu C, Ramsey LB, Karol SE, Janke LJ, Larsen EC, Winick N, Carroll WL, Loh ML, Raetz EA, Hunger SP, Devidas M, Yang JJ, Mullighan CG, Zhang J, Evans WE, Jeha S, Pui CH, Relling MV.

Clin Pharmacol Ther. 2017 Jan 16. doi: 10.1002/cpt.629. [Epub ahead of print]

PMID:
28090653
18.

Liver Enzymes and Risk of Ischemic Heart Disease and Type 2 Diabetes Mellitus: A Mendelian Randomization Study.

Liu J, Au Yeung SL, Lin SL, Leung GM, Schooling CM.

Sci Rep. 2016 Dec 20;6:38813. doi: 10.1038/srep38813.

19.

How Useful Are Monogenic Rodent Models for the Study of Human Non-Alcoholic Fatty Liver Disease?

Mann JP, Semple RK, Armstrong MJ.

Front Endocrinol (Lausanne). 2016 Nov 16;7:145. eCollection 2016. Review.

20.

Genetic and hormonal control of hepatic steatosis in female and male mice.

Norheim F, Hui ST, Kulahcioglu E, Mehrabian M, Cantor RM, Pan C, Parks BW, Lusis AJ.

J Lipid Res. 2017 Jan;58(1):178-187. doi: 10.1194/jlr.M071522. Epub 2016 Nov 3.

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