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Neutrophils are Essential in Short Hairpin RNA of Indoleamine 2,3- Dioxygenase Mediated-antitumor Efficiency.

Liu KT, Liu YH, Liu HL, Chong IW, Yen MC, Kuo PL.

Mol Ther Nucleic Acids. 2016 Dec 6;5(12):e397. doi: 10.1038/mtna.2016.105.


Hepatitis C virus drives the pathogenesis of hepatocellular carcinoma: from immune evasion to carcinogenesis.

Canavese M, Wijesundara D, Maddern GJ, Grubor-Bauk B, Hauben E.

Clin Transl Immunology. 2016 Oct 7;5(10):e101.


Molecular basis for catalysis and substrate-mediated cellular stabilization of human tryptophan 2,3-dioxygenase.

Lewis-Ballester A, Forouhar F, Kim SM, Lew S, Wang Y, Karkashon S, Seetharaman J, Batabyal D, Chiang BY, Hussain M, Correia MA, Yeh SR, Tong L.

Sci Rep. 2016 Oct 20;6:35169. doi: 10.1038/srep35169.


Third trimester phthalate exposure is associated with DNA methylation of growth-related genes in human placenta.

Zhao Y, Chen J, Wang X, Song Q, Xu HH, Zhang YH.

Sci Rep. 2016 Sep 22;6:33449. doi: 10.1038/srep33449.


Nutritional Stress Induced by Tryptophan-Degrading Enzymes Results in ATF4-Dependent Reprogramming of the Amino Acid Transporter Profile in Tumor Cells.

Timosenko E, Ghadbane H, Silk JD, Shepherd D, Gileadi U, Howson LJ, Laynes R, Zhao Q, Strausberg RL, Olsen LR, Taylor S, Buffa FM, Boyd R, Cerundolo V.

Cancer Res. 2016 Nov 1;76(21):6193-6204.


Role of Metabolism in the Immunobiology of Regulatory T Cells.

Galgani M, De Rosa V, La Cava A, Matarese G.

J Immunol. 2016 Oct 1;197(7):2567-75. doi: 10.4049/jimmunol.1600242. Review.


Identification of Interferon-Stimulated Genes with Antiretroviral Activity.

Kane M, Zang TM, Rihn SJ, Zhang F, Kueck T, Alim M, Schoggins J, Rice CM, Wilson SJ, Bieniasz PD.

Cell Host Microbe. 2016 Sep 14;20(3):392-405. doi: 10.1016/j.chom.2016.08.005.


Subpathway-CorSP: Identification of metabolic subpathways via integrating expression correlations and topological features between metabolites and genes of interest within pathways.

Feng C, Zhang J, Li X, Ai B, Han J, Wang Q, Wei T, Xu Y, Li M, Li S, Song C, Li C.

Sci Rep. 2016 Sep 14;6:33262. doi: 10.1038/srep33262.


Meta-analysis of clinical metabolic profiling studies in cancer: challenges and opportunities.

Goveia J, Pircher A, Conradi LC, Kalucka J, Lagani V, Dewerchin M, Eelen G, DeBerardinis RJ, Wilson ID, Carmeliet P.

EMBO Mol Med. 2016 Oct 4;8(10):1134-1142. doi: 10.15252/emmm.201606798.


A novel integrated gene coexpression analysis approach reveals a prognostic three-transcription-factor signature for glioma molecular subtypes.

Wu S, Li J, Cao M, Yang J, Li YX, Li YY.

BMC Syst Biol. 2016 Aug 26;10 Suppl 3:71. doi: 10.1186/s12918-016-0315-y.


An Aryl Hydrocarbon Receptor-Mediated Amplification Loop That Enforces Cell Migration in ER-/PR-/Her2- Human Breast Cancer Cells.

Novikov O, Wang Z, Stanford EA, Parks AJ, Ramirez-Cardenas A, Landesman E, Laklouk I, Sarita-Reyes C, Gusenleitner D, Li A, Monti S, Manteiga S, Lee K, Sherr DH.

Mol Pharmacol. 2016 Nov;90(5):674-688.


The Aryl Hydrocarbon Receptor Relays Metabolic Signals to Promote Cellular Regeneration.

Casado FL.

Stem Cells Int. 2016;2016:4389802. doi: 10.1155/2016/4389802. Review.


Negative Impact of Hypoxia on Tryptophan 2,3-Dioxygenase Function.

Elbers F, Woite C, Antoni V, Stein S, Funakoshi H, Nakamura T, Schares G, Däubener W, Eller SK.

Mediators Inflamm. 2016;2016:1638916. doi: 10.1155/2016/1638916.


Mucosal Interactions between Genetics, Diet, and Microbiome in Inflammatory Bowel Disease.

Basson A, Trotter A, Rodriguez-Palacios A, Cominelli F.

Front Immunol. 2016 Aug 2;7:290. doi: 10.3389/fimmu.2016.00290. Review.


Aberrant Kynurenine Signaling Modulates DNA Replication Stress Factors and Promotes Genomic Instability in Gliomas.

Bostian AC, Eoff RL.

Chem Res Toxicol. 2016 Sep 19;29(9):1369-80. doi: 10.1021/acs.chemrestox.6b00255.


Use of Plasma Metabolomics to Identify Diagnostic Biomarkers for Early Stage Epithelial Ovarian Cancer.

Fan L, Yin M, Ke C, Ge T, Zhang G, Zhang W, Zhou X, Lou G, Li K.

J Cancer. 2016 Jun 23;7(10):1265-72. doi: 10.7150/jca.15074.


The role of AHR-inducible cytochrome P450s in metabolism of polyunsaturated fatty acids.

Hankinson O.

Drug Metab Rev. 2016 Aug;48(3):342-50. doi: 10.1080/03602532.2016.1197240.


EWS-FLI1 impairs aryl hydrocarbon receptor activation by blocking tryptophan breakdown via the kynurenine pathway.

Mutz CN, Schwentner R, Kauer MO, Katschnig AM, Kromp F, Aryee DN, Erhardt S, Goiny M, Alonso J, Fuchs D, Kovar H.

FEBS Lett. 2016 Jul;590(14):2063-75. doi: 10.1002/1873-3468.12243.


Interferon-driven alterations of the host's amino acid metabolism in the pathogenesis of typhoid fever.

Blohmke CJ, Darton TC, Jones C, Suarez NM, Waddington CS, Angus B, Zhou L, Hill J, Clare S, Kane L, Mukhopadhyay S, Schreiber F, Duque-Correa MA, Wright JC, Roumeliotis TI, Yu L, Choudhary JS, Mejias A, Ramilo O, Shanyinde M, Sztein MB, Kingsley RA, Lockhart S, Levine MM, Lynn DJ, Dougan G, Pollard AJ.

J Exp Med. 2016 May 30;213(6):1061-77. doi: 10.1084/jem.20151025.


Immunometabolism of regulatory T cells.

Newton R, Priyadharshini B, Turka LA.

Nat Immunol. 2016 May 19;17(6):618-25. doi: 10.1038/ni.3466. Review.

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