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Biocomplexity and Fractality in the Search of Biomarkers of Aging and Pathology: Focus on Mitochondrial DNA and Alzheimer's Disease.

Zaia A, Maponi P, Di Stefano G, Casoli T.

Aging Dis. 2017 Feb 1;8(1):44-56. doi: 10.14336/AD.2016.0629.


A novel MTTT mutation m.15933G > A revealed in analysis of mitochondrial DNA in patients with suspected mitochondrial disease.

Soini HK, Väisänen A, Kärppä M, Hinttala R, Kytövuori L, Moilanen JS, Uusimaa J, Majamaa K.

BMC Med Genet. 2017 Feb 10;18(1):14. doi: 10.1186/s12881-017-0377-8.


A bioenergetics assay for studying the effects of environmental stressors on mitochondrial function in vivo in zebrafish larvae.

Raftery TD, Jayasundara N, Di Giulio RT.

Comp Biochem Physiol C Toxicol Pharmacol. 2017 Feb;192:23-32. doi: 10.1016/j.cbpc.2016.12.001.


Mitochondrial Haplogroup Influences Motor Function in Long-Term HIV-1-Infected Individuals.

Azar A, Devlin K, Mell JC, Giovannetti T, Pirrone V, Nonnemacher MR, Passic S, Kercher K, Williams JW, Jacobson JM, Wigdahl B, Dampier W, Libon DJ, Sell C.

PLoS One. 2016 Oct 6;11(10):e0163772. doi: 10.1371/journal.pone.0163772.


Network analysis of mitonuclear GWAS reveals functional networks and tissue expression profiles of disease-associated genes.

Johnson SC, Gonzalez B, Zhang Q, Milholland B, Zhang Z, Suh Y.

Hum Genet. 2017 Jan;136(1):55-65. doi: 10.1007/s00439-016-1736-9.


Gut Microbiota: A Modulator of Brain Plasticity and Cognitive Function in Ageing.

Leung K, Thuret S.

Healthcare (Basel). 2015 Sep 29;3(4):898-916. doi: 10.3390/healthcare3040898. Review.


Association of primary open-angle glaucoma with mitochondrial variants and haplogroups common in African Americans.

Collins DW, Gudiseva HV, Trachtman B, Bowman AS, Sagaser A, Sankar P, Miller-Ellis E, Lehman A, Addis V, O'Brien JM.

Mol Vis. 2016 May 16;22:454-71.


Genome instability in Alzheimer disease.

Hou Y, Song H, Croteau DL, Akbari M, Bohr VA.

Mech Ageing Dev. 2017 Jan;161(Pt A):83-94. doi: 10.1016/j.mad.2016.04.005.


Maternal dementia age at onset in relation to amyloid burden in non-demented elderly offspring.

Maye JE, Betensky RA, Gidicsin CM, Locascio J, Becker JA, Pepin L, Carmasin J, Rentz DM, Marshall GA, Blacker D, Sperling RA, Johnson KA.

Neurobiol Aging. 2016 Apr;40:61-7. doi: 10.1016/j.neurobiolaging.2015.12.013.


Nuclear DNA damage signalling to mitochondria in ageing.

Fang EF, Scheibye-Knudsen M, Chua KF, Mattson MP, Croteau DL, Bohr VA.

Nat Rev Mol Cell Biol. 2016 May;17(5):308-21. doi: 10.1038/nrm.2016.14. Review.


High throughput gene complementation screening permits identification of a mammalian mitochondrial protein synthesis (ρ(-)) mutant.

Potluri P, Procaccio V, Scheffler IE, Wallace DC.

Biochim Biophys Acta. 2016 Aug;1857(8):1336-43. doi: 10.1016/j.bbabio.2016.02.021.


Mitochondrial Biology and Neurological Diseases.

Arun S, Liu L, Donmez G.

Curr Neuropharmacol. 2016;14(2):143-54. Review.


PCR-Based Analysis of Mitochondrial DNA Copy Number, Mitochondrial DNA Damage, and Nuclear DNA Damage.

Gonzalez-Hunt CP, Rooney JP, Ryde IT, Anbalagan C, Joglekar R, Meyer JN.

Curr Protoc Toxicol. 2016 Feb 1;67:20.11.1-20.11.25. doi: 10.1002/0471140856.tx2011s67.


Mitochondrial retrograde signaling regulates neuronal function.

Cagin U, Duncan OF, Gatt AP, Dionne MS, Sweeney ST, Bateman JM.

Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):E6000-9. doi: 10.1073/pnas.1505036112. Erratum in: Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):E7032.


Redox control of protein degradation.

Pajares M, Jiménez-Moreno N, Dias IH, Debelec B, Vucetic M, Fladmark KE, Basaga H, Ribaric S, Milisav I, Cuadrado A.

Redox Biol. 2015 Dec;6:409-20. doi: 10.1016/j.redox.2015.07.003. Review.


High-Throughput Tissue Bioenergetics Analysis Reveals Identical Metabolic Allometric Scaling for Teleost Hearts and Whole Organisms.

Jayasundara N, Kozal JS, Arnold MC, Chan SS, Di Giulio RT.

PLoS One. 2015 Sep 14;10(9):e0137710. doi: 10.1371/journal.pone.0137710.


Role of diffuse low-level heteroplasmy of mitochondrial DNA in Alzheimer's disease neurodegeneration.

Casoli T, Spazzafumo L, Di Stefano G, Conti F.

Front Aging Neurosci. 2015 Jul 23;7:142. doi: 10.3389/fnagi.2015.00142.


RCF1-dependent respiratory supercomplexes are integral for lifespan-maintenance in a fungal ageing model.

Fischer F, Filippis C, Osiewacz HD.

Sci Rep. 2015 Jul 29;5:12697. doi: 10.1038/srep12697.

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