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An ubiquitin-dependent balance between mitofusin turnover and fatty acids desaturation regulates mitochondrial fusion.

Cavellini L, Meurisse J, Findinier J, Erpapazoglou Z, Belgareh-Touzé N, Weissman AM, Cohen MM.

Nat Commun. 2017 Jun 13;8:15832. doi: 10.1038/ncomms15832.


Dissection of ubiquitinated protein degradation by basal autophagy.

Takayama K, Matsuura A, Itakura E.

FEBS Lett. 2017 May;591(9):1199-1211. doi: 10.1002/1873-3468.12641. Epub 2017 Apr 18.


Deubiquitinating enzymes Ubp2 and Ubp15 regulate endocytosis by limiting ubiquitination and degradation of ARTs.

Ho HC, MacGurn JA, Emr SD.

Mol Biol Cell. 2017 May 1;28(9):1271-1283. doi: 10.1091/mbc.E17-01-0008. Epub 2017 Mar 15.


Changes in PUB22 Ubiquitination Modes Triggered by MITOGEN-ACTIVATED PROTEIN KINASE3 Dampen the Immune Response.

Furlan G, Nakagami H, Eschen-Lippold L, Jiang X, Majovsky P, Kowarschik K, Hoehenwarter W, Lee J, Trujillo M.

Plant Cell. 2017 Apr;29(4):726-745. doi: 10.1105/tpc.16.00654. Epub 2017 Mar 9.


Ubiquitin ligase SYVN1/HRD1 facilitates degradation of the SERPINA1 Z variant/α-1-antitrypsin Z variant via SQSTM1/p62-dependent selective autophagy.

Feng L, Zhang J, Zhu N, Ding Q, Zhang X, Yu J, Qiang W, Zhang Z, Ma Y, Huang D, Shen Y, Fang S, Yu Y, Wang H, Shen Y.

Autophagy. 2017 Apr 3;13(4):686-702. doi: 10.1080/15548627.2017.1280207. Epub 2017 Jan 25.


Evidence of an Antimicrobial Peptide Signature Encrypted in HECT E3 Ubiquitin Ligases.

Candido-Ferreira IL, Kronenberger T, Sayegh RS, Batista IF, da Silva Junior PI.

Front Immunol. 2017 Jan 9;7:664. doi: 10.3389/fimmu.2016.00664. eCollection 2016.


Yersinia pestis acetyltransferase-mediated dual acetylation at the serine and lysine residues enhances the auto-ubiquitination of ubiquitin ligase MARCH8 in human cells.

Li C, Wang D, Lv X, Jing R, Bi B, Chen X, Guo J, Wang F, Sun S, Azadzoi KM, Yang JH.

Cell Cycle. 2017 Apr 3;16(7):649-659. doi: 10.1080/15384101.2017.1281481. Epub 2017 Jan 19.


Control of Amino Acid Homeostasis by a Ubiquitin Ligase-Coactivator Protein Complex.

Guerra D, Chapiro SM, Pratelli R, Yu S, Jia W, Leary J, Pilot G, Callis J.

J Biol Chem. 2017 Mar 3;292(9):3827-3840. doi: 10.1074/jbc.M116.766469. Epub 2017 Jan 18.


Ubiquitin-coated nanodiamonds bind to autophagy receptors for entry into the selective autophagy pathway.

Liu KK, Qiu WR, Naveen Raj E, Liu HF, Huang HS, Lin YW, Chang CJ, Chen TH, Chen C, Chang HC, Hwang JK, Chao JI.

Autophagy. 2017 Jan 2;13(1):187-200. doi: 10.1080/15548627.2016.1254864. Epub 2016 Nov 15.


Epigallocatechin-3-gallate(EGCG) suppresses melanoma cell growth and metastasis by targeting TRAF6 activity.

Zhang J, Lei Z, Huang Z, Zhang X, Zhou Y, Luo Z, Zeng W, Su J, Peng C, Chen X.

Oncotarget. 2016 Nov 29;7(48):79557-79571. doi: 10.18632/oncotarget.12836.


Rottlerin inhibits cell growth and invasion via down-regulation of Cdc20 in glioma cells.

Wang L, Hou Y, Yin X, Su J, Zhao Z, Ye X, Zhou X, Zhou L, Wang Z.

Oncotarget. 2016 Oct 25;7(43):69770-69782. doi: 10.18632/oncotarget.11974.


Activation of the Yeast UBI4 Polyubiquitin Gene by Zap1 Transcription Factor via an Intragenic Promoter Is Critical for Zinc-deficient Growth.

MacDiarmid CW, Taggart J, Jeong J, Kerdsomboon K, Eide DJ.

J Biol Chem. 2016 Sep 2;291(36):18880-96. doi: 10.1074/jbc.M116.743120. Epub 2016 Jul 18.


Functions of PARylation in DNA Damage Repair Pathways.

Wei H, Yu X.

Genomics Proteomics Bioinformatics. 2016 Jun;14(3):131-9. doi: 10.1016/j.gpb.2016.05.001. Epub 2016 May 27. Review.


The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation.

Le Clorennec C, Lazrek Y, Dubreuil O, Larbouret C, Poul MA, Mondon P, Melino G, Pèlegrin A, Chardès T.

Oncotarget. 2016 Jun 14;7(24):37013-37029. doi: 10.18632/oncotarget.9455.


Proteomic Identification of Putative MicroRNA394 Target Genes in Arabidopsis thaliana Identifies Major Latex Protein Family Members Critical for Normal Development.

Litholdo CG Jr, Parker BL, Eamens AL, Larsen MR, Cordwell SJ, Waterhouse PM.

Mol Cell Proteomics. 2016 Jun;15(6):2033-47. doi: 10.1074/mcp.M115.053124. Epub 2016 Apr 11.


A decade of the anaphase-promoting complex in the nervous system.

Huang J, Bonni A.

Genes Dev. 2016 Mar 15;30(6):622-38. doi: 10.1101/gad.274324.115. Review.


18α-Glycyrrhetinic Acid Proteasome Activator Decelerates Aging and Alzheimer's Disease Progression in Caenorhabditis elegans and Neuronal Cultures.

Papaevgeniou N, Sakellari M, Jha S, Tavernarakis N, Holmberg CI, Gonos ES, Chondrogianni N.

Antioxid Redox Signal. 2016 Dec 1;25(16):855-869. Epub 2016 Mar 30.


Insights into Ubiquitination from the Unique Clamp-like Binding of the RING E3 AO7 to the E2 UbcH5B.

Li S, Liang YH, Mariano J, Metzger MB, Stringer DK, Hristova VA, Li J, Randazzo PA, Tsai YC, Ji X, Weissman AM.

J Biol Chem. 2015 Dec 18;290(51):30225-39. doi: 10.1074/jbc.M115.685867. Epub 2015 Oct 16.


EBS7 is a plant-specific component of a highly conserved endoplasmic reticulum-associated degradation system in Arabidopsis.

Liu Y, Zhang C, Wang D, Su W, Liu L, Wang M, Li J.

Proc Natl Acad Sci U S A. 2015 Sep 29;112(39):12205-10. doi: 10.1073/pnas.1511724112. Epub 2015 Sep 14.


OTUB1 inhibits the ubiquitination and degradation of FOXM1 in breast cancer and epirubicin resistance.

Karunarathna U, Kongsema M, Zona S, Gong C, Cabrera E, Gomes AR, Man EP, Khongkow P, Tsang JW, Khoo US, Medema RH, Freire R, Lam EW.

Oncogene. 2016 Mar 17;35(11):1433-44. doi: 10.1038/onc.2015.208. Epub 2015 Jul 6.

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