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Items: 1 to 20 of 28


Microtubins: a novel class of small synthetic microtubule targeting drugs that inhibit cancer cell proliferation.

Senese S, Lo YC, Gholkar AA, Li CM, Huang Y, Mottahedeh J, Kornblum HI, Damoiseaux R, Torres JZ.

Oncotarget. 2017 Oct 19;8(61):104007-104021. doi: 10.18632/oncotarget.21945. eCollection 2017 Nov 28.


Advances and challenges in the search for D2 and D3 dopamine receptor-selective compounds.

Moritz AE, Free RB, Sibley DR.

Cell Signal. 2018 Jan;41:75-81. doi: 10.1016/j.cellsig.2017.07.003. Epub 2017 Jul 14. Review.


Impact of novel miR-145-3p regulatory networks on survival in patients with castration-resistant prostate cancer.

Goto Y, Kurozumi A, Arai T, Nohata N, Kojima S, Okato A, Kato M, Yamazaki K, Ishida Y, Naya Y, Ichikawa T, Seki N.

Br J Cancer. 2017 Jul 25;117(3):409-420. doi: 10.1038/bjc.2017.191. Epub 2017 Jun 22.


Targeting glioma stem cells in vivo by a G-quadruplex-stabilizing synthetic macrocyclic hexaoxazole.

Nakamura T, Okabe S, Yoshida H, Iida K, Ma Y, Sasaki S, Yamori T, Shin-Ya K, Nakano I, Nagasawa K, Seimiya H.

Sci Rep. 2017 Jun 15;7(1):3605. doi: 10.1038/s41598-017-03785-8.


Repurposing some older drugs that cross the blood-brain barrier and have potential anticancer activity to provide new treatment options for glioblastoma.

Rundle-Thiele D, Head R, Cosgrove L, Martin JH.

Br J Clin Pharmacol. 2016 Feb;81(2):199-209. doi: 10.1111/bcp.12785. Epub 2015 Oct 30. Review.


Chemical Library Screening and Structure-Function Relationship Studies Identify Bisacodyl as a Potent and Selective Cytotoxic Agent Towards Quiescent Human Glioblastoma Tumor Stem-Like Cells.

Zeniou M, Fève M, Mameri S, Dong J, Salomé C, Chen W, El-Habr EA, Bousson F, Sy M, Obszynski J, Boh A, Villa P, Assad Kahn S, Didier B, Bagnard D, Junier MP, Chneiweiss H, Haiech J, Hibert M, Kilhoffer MC.

PLoS One. 2015 Aug 13;10(8):e0134793. doi: 10.1371/journal.pone.0134793. eCollection 2015.


Identification of thiostrepton as a novel therapeutic agent that targets human colon cancer stem cells.

Ju SY, Huang CY, Huang WC, Su Y.

Cell Death Dis. 2015 Jul 2;6:e1801. doi: 10.1038/cddis.2015.155.


Chemotherapy targeting cancer stem cells.

Liu H, Lv L, Yang K.

Am J Cancer Res. 2015 Feb 15;5(3):880-93. eCollection 2015. Review.


Anti-protozoal and anti-bacterial antibiotics that inhibit protein synthesis kill cancer subtypes enriched for stem cell-like properties.

Cuyàs E, Martin-Castillo B, Corominas-Faja B, Massaguer A, Bosch-Barrera J, Menendez JA.

Cell Cycle. 2015;14(22):3527-32. doi: 10.1080/15384101.2015.1044173.


Radiotherapy followed by aurora kinase inhibition targets tumor-propagating cells in human glioblastoma.

Li N, Maly DJ, Chanthery YH, Sirkis DW, Nakamura JL, Berger MS, James CD, Shokat KM, Weiss WA, Persson AI.

Mol Cancer Ther. 2015 Feb;14(2):419-28. doi: 10.1158/1535-7163.MCT-14-0526. Epub 2014 Dec 18.


Tackling the cancer stem cells - what challenges do they pose?

Pattabiraman DR, Weinberg RA.

Nat Rev Drug Discov. 2014 Jul;13(7):497-512. doi: 10.1038/nrd4253. Review.


Multi-kinase inhibitor C1 triggers mitotic catastrophe of glioma stem cells mainly through MELK kinase inhibition.

Minata M, Gu C, Joshi K, Nakano-Okuno M, Hong C, Nguyen CH, Kornblum HI, Molla A, Nakano I.

PLoS One. 2014 Apr 16;9(4):e92546. doi: 10.1371/journal.pone.0092546. eCollection 2014.


New molecules and old drugs as emerging approaches to selectively target human glioblastoma cancer stem cells.

Würth R, Barbieri F, Florio T.

Biomed Res Int. 2014;2014:126586. doi: 10.1155/2014/126586. Epub 2014 Jan 2. Review.


Asparagine depletion potentiates the cytotoxic effect of chemotherapy against brain tumors.

Panosyan EH, Wang Y, Xia P, Lee WN, Pak Y, Laks DR, Lin HJ, Moore TB, Cloughesy TF, Kornblum HI, Lasky JL 3rd.

Mol Cancer Res. 2014 May;12(5):694-702. doi: 10.1158/1541-7786.MCR-13-0576. Epub 2014 Feb 6.


High-throughput flow cytometry screening reveals a role for junctional adhesion molecule a as a cancer stem cell maintenance factor.

Lathia JD, Li M, Sinyuk M, Alvarado AG, Flavahan WA, Stoltz K, Rosager AM, Hale J, Hitomi M, Gallagher J, Wu Q, Martin J, Vidal JG, Nakano I, Dahlrot RH, Hansen S, McLendon RE, Sloan AE, Bao S, Hjelmeland AB, Carson CT, Naik UP, Kristensen B, Rich JN.

Cell Rep. 2014 Jan 16;6(1):117-29. doi: 10.1016/j.celrep.2013.11.043. Epub 2013 Dec 27.


Serum-free culture success of glial tumors is related to specific molecular profiles and expression of extracellular matrix-associated gene modules.

Balvers RK, Kleijn A, Kloezeman JJ, French PJ, Kremer A, van den Bent MJ, Dirven CM, Leenstra S, Lamfers ML.

Neuro Oncol. 2013 Dec;15(12):1684-95. doi: 10.1093/neuonc/not116. Epub 2013 Sep 17.


Highly penetrative, drug-loaded nanocarriers improve treatment of glioblastoma.

Zhou J, Patel TR, Sirianni RW, Strohbehn G, Zheng MQ, Duong N, Schafbauer T, Huttner AJ, Huang Y, Carson RE, Zhang Y, Sullivan DJ Jr, Piepmeier JM, Saltzman WM.

Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11751-6. doi: 10.1073/pnas.1304504110. Epub 2013 Jul 1.


Stem cells and small molecule screening: haploid embryonic stem cells as a new tool.

Wu B, Li W, Wang L, Liu ZH, Zhao XY.

Acta Pharmacol Sin. 2013 Jun;34(6):725-31. doi: 10.1038/aps.2013.26. Epub 2013 May 6. Review.


Regulation of ovarian cancer stem cells or tumor-initiating cells.

Kwon MJ, Shin YK.

Int J Mol Sci. 2013 Mar 25;14(4):6624-48. doi: 10.3390/ijms14046624. Review.

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