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Items: 1 to 20 of 64

1.

Identification of Agents Active against Methicillin-Resistant Staphylococcus aureus USA300 from a Clinical Compound Library.

Niu H, Yee R, Cui P, Tian L, Zhang S, Shi W, Sullivan D, Zhu B, Zhang W, Zhang Y.

Pathogens. 2017 Sep 20;6(3). pii: E44. doi: 10.3390/pathogens6030044.

2.

Antiplasmodial activities of dyes against Plasmodium falciparum asexual and sexual stages: Contrasted uptakes of triarylmethanes Brilliant green, Green S (E142), and Patent Blue V (E131) by erythrocytes.

Leba LJ, Popovici J, Estevez Y, Pelleau S, Legrand E, Musset L, Duplais C.

Int J Parasitol Drugs Drug Resist. 2017 Aug 2;7(3):314-320. doi: 10.1016/j.ijpddr.2017.07.002. [Epub ahead of print]

3.

Exploring anti-malarial potential of FDA approved drugs: an in silico approach.

Ramakrishnan G, Chandra N, Srinivasan N.

Malar J. 2017 Jul 18;16(1):290. doi: 10.1186/s12936-017-1937-2.

4.

A Variant PfCRT Isoform Can Contribute to Plasmodium falciparum Resistance to the First-Line Partner Drug Piperaquine.

Dhingra SK, Redhi D, Combrinck JM, Yeo T, Okombo J, Henrich PP, Cowell AN, Gupta P, Stegman ML, Hoke JM, Cooper RA, Winzeler E, Mok S, Egan TJ, Fidock DA.

MBio. 2017 May 9;8(3). pii: e00303-17. doi: 10.1128/mBio.00303-17.

5.

Drug resistance in eukaryotic microorganisms.

Fairlamb AH, Gow NA, Matthews KR, Waters AP.

Nat Microbiol. 2016 Jun 24;1(7):16092. doi: 10.1038/nmicrobiol.2016.92. Review.

6.

Molecular Mechanisms for Drug Hypersensitivity Induced by the Malaria Parasite's Chloroquine Resistance Transporter.

Richards SN, Nash MN, Baker ES, Webster MW, Lehane AM, Shafik SH, Martin RE.

PLoS Pathog. 2016 Jul 21;12(7):e1005725. doi: 10.1371/journal.ppat.1005725. eCollection 2016 Jul.

7.

Mutations in the Plasmodium falciparum Cyclic Amine Resistance Locus (PfCARL) Confer Multidrug Resistance.

LaMonte G, Lim MY, Wree M, Reimer C, Nachon M, Corey V, Gedeck P, Plouffe D, Du A, Figueroa N, Yeung B, Bifani P, Winzeler EA.

MBio. 2016 Jul 5;7(4). pii: e00696-16. doi: 10.1128/mBio.00696-16.

8.

Drug combination therapy increases successful drug repositioning.

Sun W, Sanderson PE, Zheng W.

Drug Discov Today. 2016 Jul;21(7):1189-95. doi: 10.1016/j.drudis.2016.05.015. Epub 2016 May 27. Review.

9.

PfCRT and PfMDR1 modulate interactions of artemisinin derivatives and ion channel blockers.

Eastman RT, Khine P, Huang R, Thomas CJ, Su XZ.

Sci Rep. 2016 May 5;6:25379. doi: 10.1038/srep25379.

10.

Genetic Diversity of Dihydropteroate synthetase Gene (dhps) of Plasmodium vivax in Hormozgan Province, Iran.

Maghsoodloorad S, Haghighi A, Sharifi Sarasiabi K, Taghipoor N, Hosseinzadeh N, Gachkar L, Nazemalhosseini Mojarrad E, Maghsoodloorad E.

Iran J Parasitol. 2016 Jan-Mar;11(1):98-103.

11.

Drug Development Against the Major Diarrhea-Causing Parasites of the Small Intestine, Cryptosporidium and Giardia.

Miyamoto Y, Eckmann L.

Front Microbiol. 2015 Nov 19;6:1208. doi: 10.3389/fmicb.2015.01208. eCollection 2015. Review.

12.

Chemogenomic profiling of Plasmodium falciparum as a tool to aid antimalarial drug discovery.

Pradhan A, Siwo GH, Singh N, Martens B, Balu B, Button-Simons KA, Tan A, Zhang M, Udenze KO, Jiang RH, Ferdig MT, Adams JH, Kyle DE.

Sci Rep. 2015 Nov 6;5:15930. doi: 10.1038/srep15930.

13.

Actinoramide A Identified as a Potent Antimalarial from Titration-Based Screening of Marine Natural Product Extracts.

Cheng KC, Cao S, Raveh A, MacArthur R, Dranchak P, Chlipala G, Okoneski MT, Guha R, Eastman RT, Yuan J, Schultz PJ, Su XZ, Tamayo-Castillo G, Matainaho T, Clardy J, Sherman DH, Inglese J.

J Nat Prod. 2015 Oct 23;78(10):2411-22. doi: 10.1021/acs.jnatprod.5b00489. Epub 2015 Oct 14.

14.

High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations.

Mott BT, Eastman RT, Guha R, Sherlach KS, Siriwardana A, Shinn P, McKnight C, Michael S, Lacerda-Queiroz N, Patel PR, Khine P, Sun H, Kasbekar M, Aghdam N, Fontaine SD, Liu D, Mierzwa T, Mathews-Griner LA, Ferrer M, Renslo AR, Inglese J, Yuan J, Roepe PD, Su XZ, Thomas CJ.

Sci Rep. 2015 Sep 25;5:13891. doi: 10.1038/srep13891.

15.

Profiling the Essential Nature of Lipid Metabolism in Asexual Blood and Gametocyte Stages of Plasmodium falciparum.

Gulati S, Ekland EH, Ruggles KV, Chan RB, Jayabalasingham B, Zhou B, Mantel PY, Lee MC, Spottiswoode N, Coburn-Flynn O, Hjelmqvist D, Worgall TS, Marti M, Di Paolo G, Fidock DA.

Cell Host Microbe. 2015 Sep 9;18(3):371-81. doi: 10.1016/j.chom.2015.08.003.

16.

Computational and Practical Aspects of Drug Repositioning.

Oprea TI, Overington JP.

Assay Drug Dev Technol. 2015 Jul-Aug;13(6):299-306. doi: 10.1089/adt.2015.29011.tiodrrr. Review.

17.

Genome-wide Analysis of Host-Plasmodium yoelii Interactions Reveals Regulators of the Type I Interferon Response.

Wu J, Cai B, Sun W, Huang R, Liu X, Lin M, Pattaradilokrat S, Martin S, Qi Y, Nair SC, Bolland S, Cohen JI, Austin CP, Long CA, Myers TG, Wang RF, Su XZ.

Cell Rep. 2015 Jul 28;12(4):661-72. doi: 10.1016/j.celrep.2015.06.058. Epub 2015 Jul 16.

18.

Novel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of Assays.

Lee JA, Shinn P, Jaken S, Oliver S, Willard FS, Heidler S, Peery RB, Oler J, Chu S, Southall N, Dexheimer TS, Smallwood J, Huang R, Guha R, Jadhav A, Cox K, Austin CP, Simeonov A, Sittampalam GS, Husain S, Franklin N, Wild DJ, Yang JJ, Sutherland JJ, Thomas CJ.

PLoS One. 2015 Jul 15;10(7):e0130796. doi: 10.1371/journal.pone.0130796. eCollection 2015.

19.

Predicting and exploring network components involved in pathogenesis in the malaria parasite via novel subnetwork alignments.

Cai H, Lilburn TG, Hong C, Gu J, Kuang R, Wang Y.

BMC Syst Biol. 2015;9 Suppl 4:S1. doi: 10.1186/1752-0509-9-S4-S1. Epub 2015 Jun 11.

20.

Salinomycin and other ionophores as a new class of antimalarial drugs with transmission-blocking activity.

D'Alessandro S, Corbett Y, Ilboudo DP, Misiano P, Dahiya N, Abay SM, Habluetzel A, Grande R, Gismondo MR, Dechering KJ, Koolen KM, Sauerwein RW, Taramelli D, Basilico N, Parapini S.

Antimicrob Agents Chemother. 2015 Sep;59(9):5135-44. doi: 10.1128/AAC.04332-14. Epub 2015 Jun 8.

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