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Dissecting the Influence of Two Structural Substituents on the Differential Neurotoxic Effects of Acute Methamphetamine and Mephedrone Treatment on Dopamine Nerve Endings with the Use of 4-Methylmethamphetamine and Methcathinone.

Anneken JH, Angoa-Pérez M, Sati GC, Crich D, Kuhn DM.

J Pharmacol Exp Ther. 2017 Mar;360(3):417-423. doi: 10.1124/jpet.116.237768. Epub 2016 Dec 30.


Neuropharmacology of 3,4-Methylenedioxypyrovalerone (MDPV), Its Metabolites, and Related Analogs.

Baumann MH, Bukhari MO, Lehner KR, Anizan S, Rice KC, Concheiro M, Huestis MA.

Curr Top Behav Neurosci. 2017;32:93-117. doi: 10.1007/7854_2016_53.


Structure-Activity Relationships of Substituted Cathinones, with Transporter Binding, Uptake, and Release.

Eshleman AJ, Wolfrum KM, Reed JF, Kim SO, Swanson T, Johnson RA, Janowsky A.

J Pharmacol Exp Ther. 2017 Jan;360(1):33-47. Epub 2016 Oct 31.


Synthesis, characterization and monoamine transporter activity of the new psychoactive substance mexedrone and its N-methoxy positional isomer, N-methoxymephedrone.

McLaughlin G, Morris N, Kavanagh PV, Power JD, Dowling G, Twamley B, O'Brien J, Talbot B, Walther D, Partilla JS, Baumann MH, Brandt SD.

Drug Test Anal. 2017 Mar;9(3):358-368. doi: 10.1002/dta.2053. Epub 2016 Sep 21.


Phase I metabolites of mephedrone display biological activity as substrates at monoamine transporters.

Mayer FP, Wimmer L, Dillon-Carter O, Partilla JS, Burchardt NV, Mihovilovic MD, Baumann MH, Sitte HH.

Br J Pharmacol. 2016 Sep;173(17):2657-68. doi: 10.1111/bph.13547. Epub 2016 Jul 31.


Neuropharmacology of New Psychoactive Substances (NPS): Focus on the Rewarding and Reinforcing Properties of Cannabimimetics and Amphetamine-Like Stimulants.

Miliano C, Serpelloni G, Rimondo C, Mereu M, Marti M, De Luca MA.

Front Neurosci. 2016 Apr 19;10:153. doi: 10.3389/fnins.2016.00153. eCollection 2016. Review.


Escalation of intravenous self-administration of methylone and mephedrone under extended access conditions.

Nguyen JD, Grant Y, Creehan KM, Vandewater SA, Taffe MA.

Addict Biol. 2016 Apr 5. doi: 10.1111/adb.12398. [Epub ahead of print]


Effect of Some Psychoactive Drugs Used as 'Legal Highs' on Brain Neurotransmitters.

Gołembiowska K, Jurczak A, Kamińska K, Noworyta-Sokołowska K, Górska A.

Neurotox Res. 2016 Apr;29(3):394-407. doi: 10.1007/s12640-015-9569-1. Epub 2015 Oct 26.


Mitochondrial respiratory dysfunction due to the conversion of substituted cathinones to methylbenzamides in SH-SY5Y cells.

den Hollander B, Sundström M, Pelander A, Siltanen A, Ojanperä I, Mervaala E, Korpi ER, Kankuri E.

Sci Rep. 2015 Oct 14;5:14924. doi: 10.1038/srep14924.


Intravenous self-administration of entactogen-class stimulants in male rats.

Vandewater SA, Creehan KM, Taffe MA.

Neuropharmacology. 2015 Dec;99:538-45. doi: 10.1016/j.neuropharm.2015.08.030. Epub 2015 Aug 21.


Comparative Behavioral Pharmacology of Three Pyrrolidine-Containing Synthetic Cathinone Derivatives.

Gatch MB, Dolan SB, Forster MJ.

J Pharmacol Exp Ther. 2015 Aug;354(2):103-10. doi: 10.1124/jpet.115.223586. Epub 2015 May 21.


In vivo potency and efficacy of the novel cathinone α-pyrrolidinopentiophenone and 3,4-methylenedioxypyrovalerone: self-administration and locomotor stimulation in male rats.

Aarde SM, Creehan KM, Vandewater SA, Dickerson TJ, Taffe MA.

Psychopharmacology (Berl). 2015 Aug;232(16):3045-55. doi: 10.1007/s00213-015-3944-8. Epub 2015 May 1.


Mephedrone and nicotine: oxidative stress and behavioral interactions in animal models.

Budzynska B, Boguszewska-Czubara A, Kruk-Slomka M, Kurzepa J, Biala G.

Neurochem Res. 2015 May;40(5):1083-93. doi: 10.1007/s11064-015-1566-5. Epub 2015 Apr 11.


Discriminative-stimulus effects of second generation synthetic cathinones in methamphetamine-trained rats.

Naylor JE, Freeman KB, Blough BE, Woolverton WL, Huskinson SL.

Drug Alcohol Depend. 2015 Apr 1;149:280-4. doi: 10.1016/j.drugalcdep.2015.02.002. Epub 2015 Feb 11.


Intravenous self-administration of mephedrone, methylone and MDMA in female rats.

Creehan KM, Vandewater SA, Taffe MA.

Neuropharmacology. 2015 May;92:90-7. doi: 10.1016/j.neuropharm.2015.01.003. Epub 2015 Jan 17.


'Second-generation' mephedrone analogs, 4-MEC and 4-MePPP, differentially affect monoamine transporter function.

Saha K, Partilla JS, Lehner KR, Seddik A, Stockner T, Holy M, Sandtner W, Ecker GF, Sitte HH, Baumann MH.

Neuropsychopharmacology. 2015 May;40(6):1321-31. doi: 10.1038/npp.2014.325. Epub 2014 Dec 15.


Stereochemistry and neuropharmacology of a 'bath salt' cathinone: S-enantiomer of mephedrone reduces cocaine-induced reward and withdrawal in invertebrates.

Vouga A, Gregg RA, Haidery M, Ramnath A, Al-Hassani HK, Tallarida CS, Grizzanti D, Raffa RB, Smith GR, Reitz AB, Rawls SM.

Neuropharmacology. 2015 Apr;91:109-16. doi: 10.1016/j.neuropharm.2014.11.010. Epub 2014 Dec 9.


Baths salts, spice, and related designer drugs: the science behind the headlines.

Baumann MH, Solis E Jr, Watterson LR, Marusich JA, Fantegrossi WE, Wiley JL.

J Neurosci. 2014 Nov 12;34(46):15150-8. doi: 10.1523/JNEUROSCI.3223-14.2014. Review.


Synthetic cathinones and their rewarding and reinforcing effects in rodents.

Watterson LR, Olive MF.

Adv Neurosci (Hindawi). 2014 Jun 4;2014:209875.

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