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Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development.

Shi ZD, Lee K, Yang D, Amin S, Verma N, Li QV, Zhu Z, Soh CL, Kumar R, Evans T, Chen S, Huangfu D.

Cell Stem Cell. 2017 May 4;20(5):675-688.e6. doi: 10.1016/j.stem.2017.01.001. Epub 2017 Feb 9.


β-cell replacement sources for type 1 diabetes: a focus on pancreatic ductal cells.

Corritore E, Lee YS, Sokal EM, Lysy PA.

Ther Adv Endocrinol Metab. 2016 Aug;7(4):182-99. doi: 10.1177/2042018816652059. Epub 2016 Jun 6. Review.


Genome-edited human stem cell-derived beta cells: a powerful tool for drilling down on type 2 diabetes GWAS biology.

Beer NL, Gloyn AL.

F1000Res. 2016 Jul 15;5. pii: F1000 Faculty Rev-1711. doi: 10.12688/f1000research.8682.1. eCollection 2016. Review.


Cell therapies for pancreatic beta-cell replenishment.

Okere B, Lucaccioni L, Dominici M, Iughetti L.

Ital J Pediatr. 2016 Jul 11;42(1):62. doi: 10.1186/s13052-016-0273-4. Review.


Insights into islet development and biology through characterization of a human iPSC-derived endocrine pancreas model.

van de Bunt M, Lako M, Barrett A, Gloyn AL, Hansson M, McCarthy MI, Beer NL, Honoré C.

Islets. 2016 Apr 18;8(3):83-95. doi: 10.1080/19382014.2016.1182276.


Insulin-secreting β cells require a post-genomic concept.

Jiang FX, Morahan G.

World J Diabetes. 2016 May 25;7(10):198-208. doi: 10.4239/wjd.v7.i10.198. Review.


Immunoisolation to prevent tissue graft rejection: Current knowledge and future use.

David A, Day J, Shikanov A.

Exp Biol Med (Maywood). 2016 May;241(9):955-61. doi: 10.1177/1535370216647129. Epub 2016 May 2.


Genome Editing of Lineage Determinants in Human Pluripotent Stem Cells Reveals Mechanisms of Pancreatic Development and Diabetes.

Zhu Z, Li QV, Lee K, Rosen BP, González F, Soh CL, Huangfu D.

Cell Stem Cell. 2016 Jun 2;18(6):755-68. doi: 10.1016/j.stem.2016.03.015. Epub 2016 Apr 28.


Recent Advances in Disease Modeling and Drug Discovery for Diabetes Mellitus Using Induced Pluripotent Stem Cells.

Kawser Hossain M, Abdal Dayem A, Han J, Kumar Saha S, Yang GM, Choi HY, Cho SG.

Int J Mol Sci. 2016 Feb 19;17(2):256. doi: 10.3390/ijms17020256. Review.


Integration-Free Human Induced Pluripotent Stem Cells From Type 1 Diabetes Patient Skin Fibroblasts Show Increased Abundance of Pancreas-Specific microRNAs.

Liu J, Joglekar MV, Sumer H, Hardikar AA, Teede H, Verma PJ.

Cell Med. 2014 May 2;7(1):15-24. doi: 10.3727/215517914X681785. eCollection 2014 Nov 5.


Report from IPITA-TTS Opinion Leaders Meeting on the Future of β-Cell Replacement.

Bartlett ST, Markmann JF, Johnson P, Korsgren O, Hering BJ, Scharp D, Kay TW, Bromberg J, Odorico JS, Weir GC, Bridges N, Kandaswamy R, Stock P, Friend P, Gotoh M, Cooper DK, Park CG, OʼConnell P, Stabler C, Matsumoto S, Ludwig B, Choudhary P, Kovatchev B, Rickels MR, Sykes M, Wood K, Kraemer K, Hwa A, Stanley E, Ricordi C, Zimmerman M, Greenstein J, Montanya E, Otonkoski T.

Transplantation. 2016 Feb;100 Suppl 2:S1-44. doi: 10.1097/TP.0000000000001055. No abstract available.


Human pancreatic beta-like cells converted from fibroblasts.

Zhu S, Russ HA, Wang X, Zhang M, Ma T, Xu T, Tang S, Hebrok M, Ding S.

Nat Commun. 2016 Jan 6;7:10080. doi: 10.1038/ncomms10080.


Accelerated Maturation of Human Stem Cell-Derived Pancreatic Progenitor Cells into Insulin-Secreting Cells in Immunodeficient Rats Relative to Mice.

Bruin JE, Asadi A, Fox JK, Erener S, Rezania A, Kieffer TJ.

Stem Cell Reports. 2015 Dec 8;5(6):1081-96. doi: 10.1016/j.stemcr.2015.10.013. Epub 2015 Nov 19.


STB-HO, a novel mica fine particle, inhibits the teratoma-forming ability of human embryonic stem cells after in vivo transplantation.

Choi SW, Shin TH, Uddin MH, Shin JH, Kang TW, Lee BC, Kim HS, Seo Y, Shams S, Jung YK, Kang KS.

Oncotarget. 2016 Jan 19;7(3):2684-95. doi: 10.18632/oncotarget.6472.


Insulin-Producing Endocrine Cells Differentiated In Vitro From Human Embryonic Stem Cells Function in Macroencapsulation Devices In Vivo.

Agulnick AD, Ambruzs DM, Moorman MA, Bhoumik A, Cesario RM, Payne JK, Kelly JR, Haakmeester C, Srijemac R, Wilson AZ, Kerr J, Frazier MA, Kroon EJ, D'Amour KA.

Stem Cells Transl Med. 2015 Oct;4(10):1214-22. doi: 10.5966/sctm.2015-0079. Epub 2015 Aug 24.


Concise Review: Manufacturing of Pancreatic Endoderm Cells for Clinical Trials in Type 1 Diabetes.

Schulz TC.

Stem Cells Transl Med. 2015 Aug;4(8):927-31. doi: 10.5966/sctm.2015-0058. Epub 2015 Jun 10. Review.


Stem cells for the cell and molecular therapy of type 1 diabetes mellitus (T1D): the gap between dream and reality.

Calafiore R, Basta G.

Am J Stem Cells. 2015 Mar 15;4(1):22-31. eCollection 2015. Review.

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