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Items: 1 to 20 of 88

1.

T Cells Encountering Myeloid Cells Programmed for Amino Acid-dependent Immunosuppression Use Rictor/mTORC2 Protein for Proliferative Checkpoint Decisions.

Van de Velde LA, Subramanian C, Smith AM, Barron L, Qualls JE, Neale G, Alfonso-Pecchio A, Jackowski S, Rock CO, Wynn TA, Murray PJ.

J Biol Chem. 2017 Jan 6;292(1):15-30. doi: 10.1074/jbc.M116.766238.

PMID:
27903651
2.

Essential Role of mTORC1 in Self-Renewal of Murine Alveolar Macrophages.

Deng W, Yang J, Lin X, Shin J, Gao J, Zhong XP.

J Immunol. 2017 Jan 1;198(1):492-504.

PMID:
27881705
3.

mTOR is critical for intestinal T-cell homeostasis and resistance to Citrobacter rodentium.

Lin X, Yang J, Wang J, Huang H, Wang HX, Chen P, Wang S, Pan Y, Qiu YR, Taylor GA, Vallance BA, Gao J, Zhong XP.

Sci Rep. 2016 Oct 12;6:34939. doi: 10.1038/srep34939.

4.

Critical roles of mTOR Complex 1 and 2 for T follicular helper cell differentiation and germinal center responses.

Yang J, Lin X, Pan Y, Wang J, Chen P, Huang H, Xue HH, Gao J, Zhong XP.

Elife. 2016 Sep 30;5. pii: e17936. doi: 10.7554/eLife.17936.

5.

NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.

Yang M, Chen S, Du J, He J, Wang Y, Li Z, Liu G, Peng W, Zeng X, Li D, Xu P, Guo W, Chang Z, Wang S, Tian Z, Dong Z.

Nat Commun. 2016 Sep 7;7:12730. doi: 10.1038/ncomms12730.

6.

Schlafen2 mutation unravels a role for chronic ER stress in the loss of T cell quiescence.

Omar I, Lapenna A, Cohen-Daniel L, Tirosh B, Berger M.

Oncotarget. 2016 Jun 28;7(26):39396-39407. doi: 10.18632/oncotarget.9818.

7.

Loss of T-cell quiescence by targeting Slfn2 prevents the development and progression of T-ALL.

Goldshtein A, Zerbib SM, Omar I, Cohen-Daniel L, Popkin D, Berger M.

Oncotarget. 2016 Jul 26;7(30):46835-46847. doi: 10.18632/oncotarget.9390.

8.

Immunometabolism of regulatory T cells.

Newton R, Priyadharshini B, Turka LA.

Nat Immunol. 2016 May 19;17(6):618-25. doi: 10.1038/ni.3466. Review.

9.

Metabolic maintenance of cell asymmetry following division in activated T lymphocytes.

Verbist KC, Guy CS, Milasta S, Liedmann S, Kamiński MM, Wang R, Green DR.

Nature. 2016 Apr 21;532(7599):389-93. doi: 10.1038/nature17442.

10.

Cutting Edge: Foxp1 Controls Naive CD8+ T Cell Quiescence by Simultaneously Repressing Key Pathways in Cellular Metabolism and Cell Cycle Progression.

Wei H, Geng J, Shi B, Liu Z, Wang YH, Stevens AC, Sprout SL, Yao M, Wang H, Hu H.

J Immunol. 2016 May 1;196(9):3537-41. doi: 10.4049/jimmunol.1501896.

PMID:
27001958
11.

Mechanistic Target of Rapamycin Complex 1/S6 Kinase 1 Signals Influence T Cell Activation Independently of Ribosomal Protein S6 Phosphorylation.

Salmond RJ, Brownlie RJ, Meyuhas O, Zamoyska R.

J Immunol. 2015 Nov 15;195(10):4615-22. doi: 10.4049/jimmunol.1501473.

12.

GIMAP5 Deficiency Is Associated with Increased AKT Activity in T Lymphocytes.

Chen XL, Serrano D, Mayhue M, Hoebe K, Ilangumaran S, Ramanathan S.

PLoS One. 2015 Oct 6;10(10):e0139019. doi: 10.1371/journal.pone.0139019.

13.

Metabolic regulation of T cell differentiation and function.

Park BV, Pan F.

Mol Immunol. 2015 Dec;68(2 Pt C):497-506. doi: 10.1016/j.molimm.2015.07.027. Review.

14.

T cell metabolism drives immunity.

Buck MD, O'Sullivan D, Pearce EL.

J Exp Med. 2015 Aug 24;212(9):1345-60. doi: 10.1084/jem.20151159. Review.

15.

IL-15-PI3K-AKT-mTOR: A Critical Pathway in the Life Journey of Natural Killer Cells.

Ali AK, Nandagopal N, Lee SH.

Front Immunol. 2015 Jul 20;6:355. doi: 10.3389/fimmu.2015.00355. Review.

16.

mTOR and its tight regulation for iNKT cell development and effector function.

Yang W, Gorentla B, Zhong XP, Shin J.

Mol Immunol. 2015 Dec;68(2 Pt C):536-45. doi: 10.1016/j.molimm.2015.07.022. Review.

17.

TSC1 Promotes B Cell Maturation but Is Dispensable for Germinal Center Formation.

Ci X, Kuraoka M, Wang H, Carico Z, Hopper K, Shin J, Deng X, Qiu Y, Unniraman S, Kelsoe G, Zhong XP.

PLoS One. 2015 May 22;10(5):e0127527. doi: 10.1371/journal.pone.0127527.

18.

Invariant NKT cells require autophagy to coordinate proliferation and survival signals during differentiation.

Pei B, Zhao M, Miller BC, Véla JL, Bruinsma MW, Virgin HW, Kronenberg M.

J Immunol. 2015 Jun 15;194(12):5872-84. doi: 10.4049/jimmunol.1402154.

19.

mTORC1 and mTORC2 selectively regulate CD8⁺ T cell differentiation.

Pollizzi KN, Patel CH, Sun IH, Oh MH, Waickman AT, Wen J, Delgoffe GM, Powell JD.

J Clin Invest. 2015 May;125(5):2090-108. doi: 10.1172/JCI77746.

20.

mTOR signaling and transcriptional regulation in T lymphocytes.

Zeng H, Chi H.

Transcription. 2014;5(2):e28263. doi: 10.4161/trns.28263.

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