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Pancreatic Cancer: Molecular Characterization, Clonal Evolution and Cancer Stem Cells.

Pelosi E, Castelli G, Testa U.

Biomedicines. 2017 Nov 18;5(4). pii: E65. doi: 10.3390/biomedicines5040065. Review.


Tumor engraftment in patient-derived xenografts of pancreatic ductal adenocarcinoma is associated with adverse clinicopathological features and poor survival.

Pergolini I, Morales-Oyarvide V, Mino-Kenudson M, Honselmann KC, Rosenbaum MW, Nahar S, Kem M, Ferrone CR, Lillemoe KD, Bardeesy N, Ryan DP, Thayer SP, Warshaw AL, Fernández-Del Castillo C, Liss AS.

PLoS One. 2017 Aug 30;12(8):e0182855. doi: 10.1371/journal.pone.0182855. eCollection 2017.


Alcohol and Cancer: Mechanisms and Therapies.

Ratna A, Mandrekar P.

Biomolecules. 2017 Aug 14;7(3). pii: E61. doi: 10.3390/biom7030061. Review.


Breast tumors educate the proteome of stromal tissue in an individualized but coordinated manner.

Wang X, Mooradian AD, Erdmann-Gilmore P, Zhang Q, Viner R, Davies SR, Huang KL, Bomgarden R, Van Tine BA, Shao J, Ding L, Li S, Ellis MJ, Rogers JC, Townsend RR, Fenyö D, Held JM.

Sci Signal. 2017 Aug 8;10(491). pii: eaam8065. doi: 10.1126/scisignal.aam8065.


WNT antagonists exhibit unique combinatorial antitumor activity with taxanes by potentiating mitotic cell death.

Fischer MM, Cancilla B, Yeung VP, Cattaruzza F, Chartier C, Murriel CL, Cain J, Tam R, Cheng CY, Evans JW, O'Young G, Song X, Lewicki J, Kapoun AM, Gurney A, Yen WC, Hoey T.

Sci Adv. 2017 Jun 21;3(6):e1700090. doi: 10.1126/sciadv.1700090. eCollection 2017 Jun.


Pancreatic cancer ascites xenograft-an expeditious model mirroring advanced therapeutic resistant disease.

Golan T, Stossel C, Schvimer M, Atias D, Halperin S, Buzhor E, Raitses-Gurevich M, Cohen K, Pri-Chen S, Wilson J, Denroche RE, Lungu I, Bartlett JMS, Mbabaali F, Yarden Y, Nataraj NB, Gallinger S, Berger R.

Oncotarget. 2017 Jun 20;8(25):40778-40790. doi: 10.18632/oncotarget.17253.


Development of bioluminescent chick chorioallantoic membrane (CAM) models for primary pancreatic cancer cells: a platform for drug testing.

Rovithi M, Avan A, Funel N, Leon LG, Gomez VE, Wurdinger T, Griffioen AW, Verheul HM, Giovannetti E.

Sci Rep. 2017 Mar 17;7:44686. doi: 10.1038/srep44686.


Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer.

Öhlund D, Handly-Santana A, Biffi G, Elyada E, Almeida AS, Ponz-Sarvise M, Corbo V, Oni TE, Hearn SA, Lee EJ, Chio II, Hwang CI, Tiriac H, Baker LA, Engle DD, Feig C, Kultti A, Egeblad M, Fearon DT, Crawford JM, Clevers H, Park Y, Tuveson DA.

J Exp Med. 2017 Mar 6;214(3):579-596. doi: 10.1084/jem.20162024. Epub 2017 Feb 23.


Biological basis of cancer health disparities: resources and challenges for research.

Deshmukh SK, Azim S, Ahmad A, Zubair H, Tyagi N, Srivastava SK, Bhardwaj A, Singh S, Rocconi RP, Singh AP.

Am J Cancer Res. 2017 Jan 1;7(1):1-12. eCollection 2017. Review.


Autophagy orchestrates adaptive responses to targeted therapy in endometrial cancer.

Eritja N, Chen BJ, Rodríguez-Barrueco R, Santacana M, Gatius S, Vidal A, Martí MD, Ponce J, Bergadà L, Yeramian A, Encinas M, Ribera J, Reventós J, Boyd J, Villanueva A, Matias-Guiu X, Dolcet X, Llobet-Navàs D.

Autophagy. 2017 Mar 4;13(3):608-624. doi: 10.1080/15548627.2016.1271512. Epub 2017 Jan 5.


Defining the boundaries and expanding the utility of head and neck cancer patient derived xenografts.

Swick AD, Stein AP, McCulloch TM, Hartig GK, Ong IM, Sampene E, Prabakaran PJ, Liu CZ, Kimple RJ.

Oral Oncol. 2017 Jan;64:65-72. doi: 10.1016/j.oraloncology.2016.11.017. Epub 2016 Dec 8.


Labeling of Breast Cancer Patient-derived Xenografts with Traceable Reporters for Tumor Growth and Metastasis Studies.

Hanna C, Kwok L, Finlay-Schultz J, Sartorius CA, Cittelly DM.

J Vis Exp. 2016 Nov 30;(117). doi: 10.3791/54944.


Basal Tumor Cell Isolation and Patient-Derived Xenograft Engraftment Identify High-Risk Clinical Bladder Cancers.

Skowron KB, Pitroda SP, Namm JP, Balogun O, Beckett MA, Zenner ML, Fayanju O, Huang X, Fernandez C, Zheng W, Qiao G, Chin R, Kron SJ, Khodarev NN, Posner MC, Steinberg GD, Weichselbaum RR.

Sci Rep. 2016 Oct 24;6:35854. doi: 10.1038/srep35854.


High expression of intratumoral stromal proteins is associated with chemotherapy resistance in breast cancer.

Wang T, Srivastava S, Hartman M, Buhari SA, Chan CW, Iau P, Khin LW, Wong A, Tan SH, Goh BC, Lee SC.

Oncotarget. 2016 Aug 23;7(34):55155-55168. doi: 10.18632/oncotarget.10894.


Personalized Medicine Approaches in Prostate Cancer Employing Patient Derived 3D Organoids and Humanized Mice.

Bartucci M, Ferrari AC, Kim IY, Ploss A, Yarmush M, Sabaawy HE.

Front Cell Dev Biol. 2016 Jun 23;4:64. doi: 10.3389/fcell.2016.00064. eCollection 2016. Erratum in: Front Cell Dev Biol. 2016;4:74.


Comprehensive characterization of the patient-derived xenograft and the paralleled primary hepatocellular carcinoma cell line.

Cheung PF, Yip CW, Ng LW, Lo KW, Chow C, Chan KF, Cheung TT, Cheung ST.

Cancer Cell Int. 2016 Jun 8;16:41. doi: 10.1186/s12935-016-0322-5. eCollection 2016.


Modeling pancreatic cancer with organoids.

Baker LA, Tiriac H, Clevers H, Tuveson DA.

Trends Cancer. 2016 Apr;2(4):176-190.


Whole transcriptome profiling of patient-derived xenograft models as a tool to identify both tumor and stromal specific biomarkers.

Bradford JR, Wappett M, Beran G, Logie A, Delpuech O, Brown H, Boros J, Camp NJ, McEwen R, Mazzola AM, D'Cruz C, Barry ST.

Oncotarget. 2016 Apr 12;7(15):20773-87. doi: 10.18632/oncotarget.8014.


An Integrative Approach to Precision Cancer Medicine Using Patient-Derived Xenografts.

Cho SY, Kang W, Han JY, Min S, Kang J, Lee A, Kwon JY, Lee C, Park H.

Mol Cells. 2016 Feb;39(2):77-86. doi: 10.14348/molcells.2016.2350. Epub 2016 Feb 2. Review.


Tumor-Priming Smoothened Inhibitor Enhances Deposition and Efficacy of Cytotoxic Nanoparticles in a Pancreatic Cancer Model.

Roy Chaudhuri T, Straubinger NL, Pitoniak RF, Hylander BL, Repasky EA, Ma WW, Straubinger RM.

Mol Cancer Ther. 2016 Jan;15(1):84-93. doi: 10.1158/1535-7163.MCT-15-0602. Epub 2015 Oct 29.

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