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Items: 1 to 20 of 36


Pediatric Sepsis Endotypes Among Adults With Sepsis.

Wong HR, Sweeney TE, Hart KW, Khatri P, Lindsell CJ.

Crit Care Med. 2017 Dec;45(12):e1289-e1291. doi: 10.1097/CCM.0000000000002733.


Three Hypothetical Inflammation Pathobiology Phenotypes and Pediatric Sepsis-Induced Multiple Organ Failure Outcome.

Carcillo JA, Halstead ES, Hall MW, Nguyen TC, Reeder R, Aneja R, Shakoory B, Simon D; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network Investigators.

Pediatr Crit Care Med. 2017 Jun;18(6):513-523. doi: 10.1097/PCC.0000000000001122.


Monitoring Severity of Multiple Organ Dysfunction Syndrome: New Technologies.

Typpo KV, Wong HR, Finley SD, Daniels RC, Seely AJ, Lacroix J.

Pediatr Crit Care Med. 2017 Mar;18(3_suppl Suppl 1):S24-S31. doi: 10.1097/PCC.0000000000001050. Review.


Simplification of a Septic Shock Endotyping Strategy for Clinical Application.

Wong HR, Sweeney TE, Lindsell CJ.

Am J Respir Crit Care Med. 2017 Jan 15;195(2):263-265. doi: 10.1164/rccm.201607-1535LE. No abstract available.


Host-Based Peripheral Blood Gene Expression Analysis for Diagnosis of Infectious Diseases.

Holcomb ZE, Tsalik EL, Woods CW, McClain MT.

J Clin Microbiol. 2017 Feb;55(2):360-368. doi: 10.1128/JCM.01057-16. Epub 2016 Oct 19. Review.


Emerging infection and sepsis biomarkers: will they change current therapies?

Jacobs L, Wong HR.

Expert Rev Anti Infect Ther. 2016 Oct;14(10):929-41. doi: 10.1080/14787210.2016.1222272. Epub 2016 Aug 17. Review.


Sepsis in Pediatric Cardiac Intensive Care.

Wheeler DS, Wong HR.

Pediatr Crit Care Med. 2016 Aug;17(8 Suppl 1):S266-71. doi: 10.1097/PCC.0000000000000796. Review.


Decreased CX3CR1 messenger RNA expression is an independent molecular biomarker of early and late mortality in critically ill patients.

Friggeri A, Cazalis MA, Pachot A, Cour M, Argaud L, Allaouchiche B, Floccard B, Schmitt Z, Martin O, Rimmelé T, Fontaine-Kesteloot O, Page M, Piriou V, Bohé J, Monneret G, Morisset S, Textoris J, Vallin H, Blein S, Maucort-Boulch D, Lepape A, Venet F; MIP Rea Study Group.

Crit Care. 2016 Jun 30;20(1):204. doi: 10.1186/s13054-016-1362-x.


Risk Stratification and Prognosis in Sepsis: What Have We Learned from Microarrays?

Sweeney TE, Wong HR.

Clin Chest Med. 2016 Jun;37(2):209-18. doi: 10.1016/j.ccm.2016.01.003. Epub 2016 Mar 10. Review.


Septic Shock: Advances in Diagnosis and Treatment.

Seymour CW, Rosengart MR.

JAMA. 2015 Aug 18;314(7):708-17. doi: 10.1001/jama.2015.7885. Review. Erratum in: JAMA. 2015 Oct 6;314(13):1404.


Postnatal Age Is a Critical Determinant of the Neonatal Host Response to Sepsis.

Wynn JL, Guthrie SO, Wong HR, Lahni P, Ungaro R, Lopez MC, Baker HV, Moldawer LL.

Mol Med. 2015 Jun 2;21:496-504. doi: 10.2119/molmed.2015.00064.


A comprehensive time-course-based multicohort analysis of sepsis and sterile inflammation reveals a robust diagnostic gene set.

Sweeney TE, Shidham A, Wong HR, Khatri P.

Sci Transl Med. 2015 May 13;7(287):287ra71. doi: 10.1126/scitranslmed.aaa5993.


Glucocorticoid Receptor Expression in Peripheral WBCs of Critically Ill Children.

Shibata AR, Troster EJ, Wong HR.

Pediatr Crit Care Med. 2015 Jun;16(5):e132-40. doi: 10.1097/PCC.0000000000000407.


Increased expression of neutrophil-related genes in patients with early sepsis-induced ARDS.

Kangelaris KN, Prakash A, Liu KD, Aouizerat B, Woodruff PG, Erle DJ, Rogers A, Seeley EJ, Chu J, Liu T, Osterberg-Deiss T, Zhuo H, Matthay MA, Calfee CS.

Am J Physiol Lung Cell Mol Physiol. 2015 Jun 1;308(11):L1102-13. doi: 10.1152/ajplung.00380.2014. Epub 2015 Mar 20.


Developing a clinically feasible personalized medicine approach to pediatric septic shock.

Wong HR, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald J, Checchia PA, Meyer K, Shanley TP, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Shekhar RS, Gertz S, Dawson E, Howard K, Harmon K, Beckman E, Frank E, Lindsell CJ.

Am J Respir Crit Care Med. 2015 Feb 1;191(3):309-15. doi: 10.1164/rccm.201410-1864OC.


Differential expression of the nuclear-encoded mitochondrial transcriptome in pediatric septic shock.

Weiss SL, Cvijanovich NZ, Allen GL, Thomas NJ, Freishtat RJ, Anas N, Meyer K, Checchia PA, Shanley TP, Bigham MT, Fitzgerald J, Banschbach S, Beckman E, Howard K, Frank E, Harmon K, Wong HR.

Crit Care. 2014 Nov 19;18(6):623. doi: 10.1186/s13054-014-0623-9.


Identifying critically ill patients who may benefit from adjunctive corticosteroids: not as easy as we thought.

Atkinson SJ, Wong HR.

Pediatr Crit Care Med. 2014 Oct;15(8):769-71. doi: 10.1097/PCC.0000000000000203. No abstract available.


A functional synonymous coding variant in the IL1RN gene is associated with survival in septic shock.

Meyer NJ, Ferguson JF, Feng R, Wang F, Patel PN, Li M, Xue C, Qu L, Liu Y, Boyd JH, Russell JA, Christie JD, Walley KR, Reilly MP.

Am J Respir Crit Care Med. 2014 Sep 15;190(6):656-64. doi: 10.1164/rccm.201403-0586OC.


Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials.

Calfee CS, Delucchi K, Parsons PE, Thompson BT, Ware LB, Matthay MA; NHLBI ARDS Network.

Lancet Respir Med. 2014 Aug;2(8):611-20. doi: 10.1016/S2213-2600(14)70097-9. Epub 2014 May 19.


Time for a neonatal-specific consensus definition for sepsis.

Wynn JL, Wong HR, Shanley TP, Bizzarro MJ, Saiman L, Polin RA.

Pediatr Crit Care Med. 2014 Jul;15(6):523-8. doi: 10.1097/PCC.0000000000000157. Review.

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