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Items: 1 to 20 of 47


Historical perspective on heart function: the Frank-Starling Law.

Sequeira V, van der Velden J.

Biophys Rev. 2015 Dec;7(4):421-447. doi: 10.1007/s12551-015-0184-4. Epub 2015 Nov 19. Review.


Myosin filament activation in the heart is tuned to the mechanical task.

Reconditi M, Caremani M, Pinzauti F, Powers JD, Narayanan T, Stienen GJ, Linari M, Lombardi V, Piazzesi G.

Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):3240-3245. doi: 10.1073/pnas.1619484114. Epub 2017 Mar 6.


Distinct contributions of the thin and thick filaments to length-dependent activation in heart muscle.

Zhang X, Kampourakis T, Yan Z, Sevrieva I, Irving M, Sun YB.

Elife. 2017 Feb 23;6. pii: e24081. doi: 10.7554/eLife.24081.


Phosphorylation of cardiac myosin binding protein C releases myosin heads from the surface of cardiac thick filaments.

Kensler RW, Craig R, Moss RL.

Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):E1355-E1364. doi: 10.1073/pnas.1614020114. Epub 2017 Feb 6.


In vivo definition of cardiac myosin-binding protein C's critical interactions with myosin.

Bhuiyan MS, McLendon P, James J, Osinska H, Gulick J, Bhandary B, Lorenz JN, Robbins J.

Pflugers Arch. 2016 Oct;468(10):1685-95. doi: 10.1007/s00424-016-1873-y. Epub 2016 Aug 27.


Alterations in Multi-Scale Cardiac Architecture in Association With Phosphorylation of Myosin Binding Protein-C.

Taylor EN, Hoffman MP, Barefield DY, Aninwene GE 2nd, Abrishamchi AD, Lynch TL 4th, Govindan S, Osinska H, Robbins J, Sadayappan S, Gilbert RJ.

J Am Heart Assoc. 2016 Mar 15;5(3):e002836. doi: 10.1161/JAHA.115.002836.


Myosin filament sliding through the Z-disc relates striated muscle fibre structure to function.

Rode C, Siebert T, Tomalka A, Blickhan R.

Proc Biol Sci. 2016 Mar 16;283(1826):20153030. doi: 10.1098/rspb.2015.3030.


Phosphorylation and calcium antagonistically tune myosin-binding protein C's structure and function.

Previs MJ, Mun JY, Michalek AJ, Previs SB, Gulick J, Robbins J, Warshaw DM, Craig R.

Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3239-44. doi: 10.1073/pnas.1522236113. Epub 2016 Feb 23.


Molecule specific effects of PKA-mediated phosphorylation on rat isolated heart and cardiac myofibrillar function.

Hanft LM, Cornell TD, McDonald CA, Rovetto MJ, Emter CA, McDonald KS.

Arch Biochem Biophys. 2016 Jul 1;601:22-31. doi: 10.1016/ Epub 2016 Feb 15.


C0 and C1 N-terminal Ig domains of myosin binding protein C exert different effects on thin filament activation.

Harris SP, Belknap B, Van Sciver RE, White HD, Galkin VE.

Proc Natl Acad Sci U S A. 2016 Feb 9;113(6):1558-63. doi: 10.1073/pnas.1518891113. Epub 2016 Feb 1.


ADP-stimulated contraction: A predictor of thin-filament activation in cardiac disease.

Sequeira V, Najafi A, Wijnker PJ, Dos Remedios CG, Michels M, Kuster DW, van der Velden J.

Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):E7003-12. doi: 10.1073/pnas.1513843112. Epub 2015 Nov 30.


Cardiac Myosin-binding Protein C and Troponin-I Phosphorylation Independently Modulate Myofilament Length-dependent Activation.

Kumar M, Govindan S, Zhang M, Khairallah RJ, Martin JL, Sadayappan S, de Tombe PP.

J Biol Chem. 2015 Dec 4;290(49):29241-9. doi: 10.1074/jbc.M115.686790. Epub 2015 Oct 9.


The Conformation of Myosin Heads in Relaxed Skeletal Muscle: Implications for Myosin-Based Regulation.

Fusi L, Huang Z, Irving M.

Biophys J. 2015 Aug 18;109(4):783-92. doi: 10.1016/j.bpj.2015.06.038.


Through Thick and Thin--Interfilament Communication in Muscle.

Woodhead JL, Craig R.

Biophys J. 2015 Aug 18;109(4):665-7. doi: 10.1016/j.bpj.2015.07.019. No abstract available.


Myosin-binding protein C corrects an intrinsic inhomogeneity in cardiac excitation-contraction coupling.

Previs MJ, Prosser BL, Mun JY, Previs SB, Gulick J, Lee K, Robbins J, Craig R, Lederer WJ, Warshaw DM.

Sci Adv. 2015;1(1). pii: e1400205.


Orientation of the N- and C-terminal lobes of the myosin regulatory light chain in cardiac muscle.

Kampourakis T, Sun YB, Irving M.

Biophys J. 2015 Jan 20;108(2):304-14. doi: 10.1016/j.bpj.2014.11.049.


Myosin binding protein-C activates thin filaments and inhibits thick filaments in heart muscle cells.

Kampourakis T, Yan Z, Gautel M, Sun YB, Irving M.

Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18763-8. doi: 10.1073/pnas.1413922112. Epub 2014 Dec 15.


Orientation of myosin binding protein C in the cardiac muscle sarcomere determined by domain-specific immuno-EM.

Lee K, Harris SP, Sadayappan S, Craig R.

J Mol Biol. 2015 Jan 30;427(2):274-86. doi: 10.1016/j.jmb.2014.10.023. Epub 2014 Nov 6.


Kinetics of cardiac myosin isoforms in mouse myocardium are affected differently by presence of myosin binding protein-C.

Tanner BC, Wang Y, Robbins J, Palmer BM.

J Muscle Res Cell Motil. 2014 Dec;35(5-6):267-78. doi: 10.1007/s10974-014-9390-0. Epub 2014 Oct 7.


Zebrafish cardiac muscle thick filaments: isolation technique and three-dimensional structure.

González-Solá M, Al-Khayat HA, Behra M, Kensler RW.

Biophys J. 2014 Apr 15;106(8):1671-80. doi: 10.1016/j.bpj.2014.01.050.

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