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Items: 1 to 20 of 121


Clinicopathological and prognostic significance of PKM2 protein expression in cirrhotic hepatocellular carcinoma and non-cirrhotic hepatocellular carcinoma.

Liu Y, Wu H, Mei Y, Ding X, Yang X, Li C, Deng M, Gong J.

Sci Rep. 2017 Nov 10;7(1):15294. doi: 10.1038/s41598-017-14813-y.


NOX4 functions as a mitochondrial energetic sensor coupling cancer metabolic reprogramming to drug resistance.

Shanmugasundaram K, Nayak BK, Friedrichs WE, Kaushik D, Rodriguez R, Block K.

Nat Commun. 2017 Oct 19;8(1):997. doi: 10.1038/s41467-017-01106-1.


Impaired p65 degradation by decreased chaperone-mediated autophagy activity facilitates epithelial-to-mesenchymal transition.

Tang J, Zhan MN, Yin QQ, Zhou CX, Wang CL, Wo LL, He M, Chen GQ, Zhao Q.

Oncogenesis. 2017 Oct 9;6(10):e387. doi: 10.1038/oncsis.2017.85.


Chaperone-mediated autophagy substrate proteins in cancer.

Tang Y, Wang XW, Liu ZH, Sun YM, Tang YX, Zhou DH.

Oncotarget. 2017 May 3;8(31):51970-51985. doi: 10.18632/oncotarget.17583. eCollection 2017 Aug 1. Review.


Enoyl-CoA hydratase-1 regulates mTOR signaling and apoptosis by sensing nutrients.

Zhang YK, Qu YY, Lin Y, Wu XH, Chen HZ, Wang X, Zhou KQ, Wei Y, Guo F, Yao CF, He XD, Liu LX, Yang C, Guan ZY, Wang SD, Zhao J, Liu DP, Zhao SM, Xu W.

Nat Commun. 2017 Sep 6;8(1):464. doi: 10.1038/s41467-017-00489-5.


The Warburg Effect and Mass Spectrometry-based Proteomic Analysis.

Zhou W, Liotta LA, Petricoin EF.

Cancer Genomics Proteomics. 2017 Jul-Aug;14(4):211-218. Review.


Associations among Metabolism, Circadian Rhythm and Age-Associated Diseases.

Cao Y, Wang RH.

Aging Dis. 2017 May 2;8(3):314-333. doi: 10.14336/AD.2016.1101. eCollection 2017 May. Review.


Identification of a multienzyme complex for glucose metabolism in living cells.

Kohnhorst CL, Kyoung M, Jeon M, Schmitt DL, Kennedy EL, Ramirez J, Bracey SM, Luu BT, Russell SJ, An S.

J Biol Chem. 2017 Jun 2;292(22):9191-9203. doi: 10.1074/jbc.M117.783050. Epub 2017 Apr 19.


Chaperone-mediated autophagy prevents cellular transformation by regulating MYC proteasomal degradation.

Gomes LR, Menck CFM, Cuervo AM.

Autophagy. 2017 May 4;13(5):928-940. doi: 10.1080/15548627.2017.1293767. Epub 2017 Mar 2.


Gcn5-mediated Rph1 acetylation regulates its autophagic degradation under DNA damage stress.

Li F, Zheng LD, Chen X, Zhao X, Briggs SD, Du HN.

Nucleic Acids Res. 2017 May 19;45(9):5183-5197. doi: 10.1093/nar/gkx129.


Acetylation targets HSD17B4 for degradation via the CMA pathway in response to estrone.

Zhang Y, Xu YY, Yao CB, Li JT, Zhao XN, Yang HB, Zhang M, Yin M, Chen J, Lei QY.

Autophagy. 2017 Mar 4;13(3):538-553. doi: 10.1080/15548627.2016.1268302. Epub 2017 Feb 22.


Autophagy and Autophagy-Related Proteins in CNS Autoimmunity.

Keller CW, L√ľnemann JD.

Front Immunol. 2017 Feb 27;8:165. doi: 10.3389/fimmu.2017.00165. eCollection 2017. Review.


HDAC6-mediated acetylation of lipid droplet-binding protein CIDEC regulates fat-induced lipid storage.

Qian H, Chen Y, Nian Z, Su L, Yu H, Chen FJ, Zhang X, Xu W, Zhou L, Liu J, Yu J, Yu L, Gao Y, Zhang H, Zhang H, Zhao S, Yu L, Xiao RP, Bao Y, Hou S, Li P, Li J, Deng H, Jia W, Li P.

J Clin Invest. 2017 Apr 3;127(4):1353-1369. doi: 10.1172/JCI85963. Epub 2017 Mar 13.


Serine phosphorylation of the cotton cytosolic pyruvate kinase GhPK6 decreases its stability and activity.

Zhang B, Liu JY.

FEBS Open Bio. 2017 Jan 25;7(3):358-366. doi: 10.1002/2211-5463.12179. eCollection 2017 Mar.


Will Quantitative Proteomics Redefine Some of the Key Concepts in Skeletal Muscle Physiology?

Gizak A, Rakus D.

Proteomes. 2016 Jan 11;4(1). pii: E2. doi: 10.3390/proteomes4010002.


Combination of Arsenic trioxide and Everolimus (Rad001) synergistically induces both autophagy and apoptosis in prostate cancer cells.

Tai S, Xu L, Xu M, Zhang L, Zhang Y, Zhang K, Zhang L, Liang C.

Oncotarget. 2017 Feb 14;8(7):11206-11218. doi: 10.18632/oncotarget.14493.


Desuccinylation of pyruvate kinase M2 by SIRT5 contributes to antioxidant response and tumor growth.

Xiangyun Y, Xiaomin N, Linping G, Yunhua X, Ziming L, Yongfeng Y, Zhiwei C, Shun L.

Oncotarget. 2017 Jan 24;8(4):6984-6993. doi: 10.18632/oncotarget.14346.


The Warburg Effect Mediator Pyruvate Kinase M2 Expression and Regulation in the Retina.

Rajala RV, Rajala A, Kooker C, Wang Y, Anderson RE.

Sci Rep. 2016 Nov 24;6:37727. doi: 10.1038/srep37727.


Tetrameric Acetyl-CoA Acetyltransferase 1 Is Important for Tumor Growth.

Fan J, Lin R, Xia S, Chen D, Elf SE, Liu S, Pan Y, Xu H, Qian Z, Wang M, Shan C, Zhou L, Lei QY, Li Y, Mao H, Lee BH, Sudderth J, DeBerardinis RJ, Zhang G, Owonikoko T, Gaddh M, Arellano ML, Khoury HJ, Khuri FR, Kang S, Doetsch PW, Lonial S, Boggon TJ, Curran WJ, Chen J.

Mol Cell. 2016 Dec 1;64(5):859-874. doi: 10.1016/j.molcel.2016.10.014. Epub 2016 Nov 17.


PKM2, cancer metabolism, and the road ahead.

Dayton TL, Jacks T, Vander Heiden MG.

EMBO Rep. 2016 Dec;17(12):1721-1730. Epub 2016 Nov 17. Review.


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