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Items: 1 to 20 of 22

1.

Base Excision Repair, a Pathway Regulated by Posttranslational Modifications.

Carter RJ, Parsons JL.

Mol Cell Biol. 2016 May 2;36(10):1426-37. doi: 10.1128/MCB.00030-16. Print 2016 May 15. Review.

2.

The Response to Oxidative DNA Damage in Neurons: Mechanisms and Disease.

Narciso L, Parlanti E, Racaniello M, Simonelli V, Cardinale A, Merlo D, Dogliotti E.

Neural Plast. 2016;2016:3619274. doi: 10.1155/2016/3619274. Epub 2016 Jan 31. Review.

3.

Polynucleotide kinase-phosphatase enables neurogenesis via multiple DNA repair pathways to maintain genome stability.

Shimada M, Dumitrache LC, Russell HR, McKinnon PJ.

EMBO J. 2015 Oct 1;34(19):2465-80. doi: 10.15252/embj.201591363. Epub 2015 Aug 19.

4.

Mutations in PNKP cause recessive ataxia with oculomotor apraxia type 4.

Bras J, Alonso I, Barbot C, Costa MM, Darwent L, Orme T, Sequeiros J, Hardy J, Coutinho P, Guerreiro R.

Am J Hum Genet. 2015 Mar 5;96(3):474-9. doi: 10.1016/j.ajhg.2015.01.005. Epub 2015 Feb 26.

5.

The role of the mammalian DNA end-processing enzyme polynucleotide kinase 3'-phosphatase in spinocerebellar ataxia type 3 pathogenesis.

Chatterjee A, Saha S, Chakraborty A, Silva-Fernandes A, Mandal SM, Neves-Carvalho A, Liu Y, Pandita RK, Hegde ML, Hegde PM, Boldogh I, Ashizawa T, Koeppen AH, Pandita TK, Maciel P, Sarkar PS, Hazra TK.

PLoS Genet. 2015 Jan 29;11(1):e1004749. doi: 10.1371/journal.pgen.1004749. eCollection 2015 Jan.

6.

Pioglitazone restores IGFBP-3 levels through DNA PK in retinal endothelial cells cultured in hyperglycemic conditions.

Thakran S, Zhang Q, Morales-Tirado V, Steinle JJ.

Invest Ophthalmol Vis Sci. 2014 Dec 18;56(1):177-84. doi: 10.1167/iovs.14-15550.

7.

Interplay of DNA damage and cell cycle signaling at the level of human replication protein A.

Borgstahl GE, Brader K, Mosel A, Liu S, Kremmer E, Goettsch KA, Kolar C, Nasheuer HP, Oakley GG.

DNA Repair (Amst). 2014 Sep;21:12-23. doi: 10.1016/j.dnarep.2014.05.005. Epub 2014 Jun 13.

8.

Monitoring regulation of DNA repair activities of cultured cells in-gel using the comet assay.

Nickson CM, Parsons JL.

Front Genet. 2014 Jul 16;5:232. doi: 10.3389/fgene.2014.00232. eCollection 2014. Review.

9.

Structural insights into NHEJ: building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a time.

Williams GJ, Hammel M, Radhakrishnan SK, Ramsden D, Lees-Miller SP, Tainer JA.

DNA Repair (Amst). 2014 May;17:110-20. doi: 10.1016/j.dnarep.2014.02.009. Epub 2014 Mar 20. Review.

10.

Non-homologous end joining: emerging themes and unanswered questions.

Radhakrishnan SK, Jette N, Lees-Miller SP.

DNA Repair (Amst). 2014 May;17:2-8. doi: 10.1016/j.dnarep.2014.01.009. Epub 2014 Feb 26. Review.

11.

Severe hypoxia induces complete antifolate resistance in carcinoma cells due to cell cycle arrest.

Raz S, Sheban D, Gonen N, Stark M, Berman B, Assaraf YG.

Cell Death Dis. 2014 Feb 20;5:e1067. doi: 10.1038/cddis.2014.39.

12.

ATM deficiency results in accumulation of DNA-topoisomerase I covalent intermediates in neural cells.

Alagoz M, Chiang SC, Sharma A, El-Khamisy SF.

PLoS One. 2013 Apr 23;8(4):e58239. doi: 10.1371/journal.pone.0058239. Print 2013.

13.

The ATM signaling network in development and disease.

Stracker TH, Roig I, Knobel PA, Marjanović M.

Front Genet. 2013 Mar 25;4:37. doi: 10.3389/fgene.2013.00037. eCollection 2013.

14.

The PARP3- and ATM-dependent phosphorylation of APLF facilitates DNA double-strand break repair.

Fenton AL, Shirodkar P, Macrae CJ, Meng L, Koch CA.

Nucleic Acids Res. 2013 Apr;41(7):4080-92. doi: 10.1093/nar/gkt134. Epub 2013 Feb 28.

15.

Detection and repair of ionizing radiation-induced DNA double strand breaks: new developments in nonhomologous end joining.

Wang C, Lees-Miller SP.

Int J Radiat Oncol Biol Phys. 2013 Jul 1;86(3):440-9. doi: 10.1016/j.ijrobp.2013.01.011. Epub 2013 Feb 20. Review.

16.

Resolution of complex ends by Nonhomologous end joining - better to be lucky than good?

Strande NT, Waters CA, Ramsden DA.

Genome Integr. 2012 Dec 31;3(1):10. doi: 10.1186/2041-9414-3-10.

17.

Phosphorylation of PNKP by ATM prevents its proteasomal degradation and enhances resistance to oxidative stress.

Parsons JL, Khoronenkova SV, Dianova II, Ternette N, Kessler BM, Datta PK, Dianov GL.

Nucleic Acids Res. 2012 Dec;40(22):11404-15. doi: 10.1093/nar/gks909. Epub 2012 Oct 5.

18.

DNA double strand breaks but not interstrand crosslinks prevent progress through meiosis in fully grown mouse oocytes.

Yuen WS, Merriman JA, O'Bryan MK, Jones KT.

PLoS One. 2012;7(8):e43875. doi: 10.1371/journal.pone.0043875. Epub 2012 Aug 22.

19.

Impact of PNKP mutations associated with microcephaly, seizures and developmental delay on enzyme activity and DNA strand break repair.

Reynolds JJ, Walker AK, Gilmore EC, Walsh CA, Caldecott KW.

Nucleic Acids Res. 2012 Aug;40(14):6608-19. doi: 10.1093/nar/gks318. Epub 2012 Apr 15.

20.

SUMO modification of the neuroprotective protein TDP1 facilitates chromosomal single-strand break repair.

Hudson JJ, Chiang SC, Wells OS, Rookyard C, El-Khamisy SF.

Nat Commun. 2012 Mar 13;3:733. doi: 10.1038/ncomms1739.

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