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Items: 10


Hes1 promotes cell proliferation and migration by activating Bmi-1 and PTEN/Akt/GSK3β pathway in human colon cancer.

Gao F, Huang W, Zhang Y, Tang S, Zheng L, Ma F, Wang Y, Tang H, Li X.

Oncotarget. 2015 Nov 17;6(36):38667-80. doi: 10.18632/oncotarget.5484.


Role of PAR-4 in ovarian cancer.

Meynier S, Kramer M, Ribaux P, Tille JC, Delie F, Petignat P, Cohen M.

Oncotarget. 2015 Sep 8;6(26):22641-52.


The tumor suppressor prostate apoptosis response-4 (Par-4) is regulated by mutant IDH1 and kills glioma stem cells.

Liu Y, Gilbert MR, Kyprianou N, Rangnekar VM, Horbinski C.

Acta Neuropathol. 2014 Nov;128(5):723-32. doi: 10.1007/s00401-014-1334-7. Epub 2014 Aug 19.


Identification of glycogen synthase kinase 3α as a therapeutic target in melanoma.

Madhunapantula SV, Sharma A, Gowda R, Robertson GP.

Pigment Cell Melanoma Res. 2013 Nov;26(6):886-99. doi: 10.1111/pcmr.12156. Epub 2013 Sep 19.


The Akt inhibitor ISC-4 synergizes with cetuximab in 5-FU-resistant colon cancer.

Allen JE, Gallant JN, Dicker DT, Amin S, Irby RB, Sharma AK, El-Deiry WS.

PLoS One. 2013;8(3):e59380. doi: 10.1371/journal.pone.0059380. Epub 2013 Mar 12. Erratum in: PLoS One. 2013;8(11). doi:10.1371/annotation/aaa12360-0c90-42c3-bc43-d00022b68b81.


Phenylalkyl isoselenocyanates vs phenylalkyl isothiocyanates: thiol reactivity and its implications.

Crampsie MA, Pandey MK, Desai D, Spallholz J, Amin S, Sharma AK.

Chem Biol Interact. 2012 Oct 25;200(1):28-37. doi: 10.1016/j.cbi.2012.08.022. Epub 2012 Sep 13.


Chemoprevention of melanoma.

Madhunapantula SV, Robertson GP.

Adv Pharmacol. 2012;65:361-98. doi: 10.1016/B978-0-12-397927-8.00012-9. Review.


Selenium compounds, apoptosis and other types of cell death: an overview for cancer therapy.

Sanmartín C, Plano D, Sharma AK, Palop JA.

Int J Mol Sci. 2012;13(8):9649-72. doi: 10.3390/ijms13089649. Epub 2012 Aug 2. Review.


Rational incorporation of selenium into temozolomide elicits superior antitumor activity associated with both apoptotic and autophagic cell death.

Cheng Y, Sk UH, Zhang Y, Ren X, Zhang L, Huber-Keener KJ, Sun YW, Liao J, Amin S, Sharma AK, Yang JM.

PLoS One. 2012;7(4):e35104. doi: 10.1371/journal.pone.0035104. Epub 2012 Apr 5.


Synthesis and biological evaluation of a novel class of isatin analogs as dual inhibitors of tubulin polymerization and Akt pathway.

Krishnegowda G, Prakasha Gowda AS, Tagaram HR, Carroll KF, Irby RB, Sharma AK, Amin S.

Bioorg Med Chem. 2011 Oct 15;19(20):6006-14. doi: 10.1016/j.bmc.2011.08.044. Epub 2011 Aug 26.

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