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Items: 1 to 20 of 27


The E3 ubiquitin ligase RNF185 facilitates the cGAS-mediated innate immune response.

Wang Q, Huang L, Hong Z, Lv Z, Mao Z, Tang Y, Kong X, Li S, Cui Y, Liu H, Zhang L, Zhang X, Jiang L, Wang C, Zhou Q.

PLoS Pathog. 2017 Mar 8;13(3):e1006264. doi: 10.1371/journal.ppat.1006264. eCollection 2017 Mar.


DNA vaccines for prostate cancer.

Zahm CD, Colluru VT, McNeel DG.

Pharmacol Ther. 2017 Jun;174:27-42. doi: 10.1016/j.pharmthera.2017.02.016. Epub 2017 Feb 7. Review.


Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents.

Gaston J, Cheradame L, Yvonnet V, Deas O, Poupon MF, Judde JG, Cairo S, Goffin V.

Oncotarget. 2016 Nov 22;7(47):77205-77224. doi: 10.18632/oncotarget.12858.


STING Contributes to Abnormal Bone Formation Induced by Deficiency of DNase II in Mice.

Baum R, Sharma S, Organ JM, Jakobs C, Hornung V, Burr DB, Marshak-Rothstein A, Fitzgerald KA, Gravallese EM.

Arthritis Rheumatol. 2017 Feb;69(2):460-471. doi: 10.1002/art.39863.


Taking the STING out of TLR-driven autoimmune diseases: good, bad, or indifferent?

Pawaria S, Sharma S, Baum R, Nündel K, Busto P, Gravallese EM, Fitzgerald KA, Marshak-Rothstein A.

J Leukoc Biol. 2017 Jan;101(1):121-126. doi: 10.1189/jlb.3MR0316-115R. Epub 2016 Aug 16. Review.


Molecular characterization of woodchuck IFI16 and AIM2 and their expression in woodchucks infected with woodchuck hepatitis virus (WHV).

Yan Q, Li M, Liu Q, Li F, Zhu B, Wang J, Lu Y, Liu J, Wu J, Zheng X, Lu M, Wang B, Yang D.

Sci Rep. 2016 Jun 29;6:28776. doi: 10.1038/srep28776.


Synergy between Hematopoietic and Radioresistant Stromal Cells Is Required for Autoimmune Manifestations of DNase II-/-IFNaR-/- Mice.

Baum R, Nündel K, Pawaria S, Sharma S, Busto P, Fitzgerald KA, Gravallese EM, Marshak-Rothstein A.

J Immunol. 2016 Feb 1;196(3):1348-54. doi: 10.4049/jimmunol.1502130. Epub 2016 Jan 4.


An unexpected role for RNA-sensing toll-like receptors in a murine model of DNA accrual.

Pawaria S, Moody KL, Busto P, Nündel K, Baum R, Sharma S, Gravallese EM, Fitzgerald KA, Marshak-Rothstein A.

Clin Exp Rheumatol. 2015 Jul-Aug;33(4 Suppl 92):S70-3. Epub 2015 Oct 12. Review.


Combination of cyclophosphamide and double-stranded DNA demonstrates synergistic toxicity against established xenografts.

Alyamkina EA, Nikolin VP, Popova NA, Minkevich AM, Kozel AV, Dolgova EV, Efremov YR, Bayborodin SI, Andrushkevich OM, Taranov OS, Omigov VV, Rogachev VA, Proskurina AS, Vereschagin EI, Kiseleva EV, Zhukova MV, Ostanin AA, Chernykh ER, Bogachev SS, Shurdov MA.

Cancer Cell Int. 2015 Mar 19;15:32. doi: 10.1186/s12935-015-0180-6. eCollection 2015.


A transcriptome analysis suggests apoptosis-related signaling pathways in hemocytes of Spodoptera litura after parasitization by Microplitis bicoloratus.

Li M, Pang Z, Xiao W, Liu X, Zhang Y, Yu D, Yang M, Yang Y, Hu J, Luo K.

PLoS One. 2014 Oct 28;9(10):e110967. doi: 10.1371/journal.pone.0110967. eCollection 2014.


Cell death and DAMPs in acute pancreatitis.

Kang R, Lotze MT, Zeh HJ, Billiar TR, Tang D.

Mol Med. 2014 Oct 29;20:466-77. doi: 10.2119/molmed.2014.00117. Review.


Intracellular immunity: finding the enemy within--how cells recognize and respond to intracellular pathogens.

Tam JC, Jacques DA.

J Leukoc Biol. 2014 Aug;96(2):233-44. doi: 10.1189/jlb.4RI0214-090R. Epub 2014 Jun 4.


RNA and β-hemolysin of group B Streptococcus induce interleukin-1β (IL-1β) by activating NLRP3 inflammasomes in mouse macrophages.

Gupta R, Ghosh S, Monks B, DeOliveira RB, Tzeng TC, Kalantari P, Nandy A, Bhattacharjee B, Chan J, Ferreira F, Rathinam V, Sharma S, Lien E, Silverman N, Fitzgerald K, Firon A, Trieu-Cuot P, Henneke P, Golenbock DT.

J Biol Chem. 2014 May 16;289(20):13701-5. doi: 10.1074/jbc.C114.548982. Epub 2014 Apr 1.


Pattern recognition receptors in innate immunity, host defense, and immunopathology.

Suresh R, Mosser DM.

Adv Physiol Educ. 2013 Dec;37(4):284-91. doi: 10.1152/advan.00058.2013.


Type I interferon and lymphangiogenesis in the HSV-1 infected cornea - are they beneficial to the host?

Bryant-Hudson K, Conrady CD, Carr DJ.

Prog Retin Eye Res. 2013 Sep;36:281-91. doi: 10.1016/j.preteyeres.2013.06.003. Epub 2013 Jul 19. Review.


Reprogramming of murine macrophages through TLR2 confers viral resistance via TRAF3-mediated, enhanced interferon production.

Perkins DJ, Polumuri SK, Pennini ME, Lai W, Xie P, Vogel SN.

PLoS Pathog. 2013;9(7):e1003479. doi: 10.1371/journal.ppat.1003479. Epub 2013 Jul 11.


Nucleofection of expression vectors induces a robust interferon response and inhibition of cell proliferation.

Huerfano S, Ryabchenko B, Forstová J.

DNA Cell Biol. 2013 Aug;32(8):467-79. doi: 10.1089/dna.2012.1950. Epub 2013 Jun 8.


The importance of becoming double-stranded: Innate immunity and the kinetic model of HIV-1 central plus strand synthesis.

Poeschla E.

Virology. 2013 Jun 20;441(1):1-11. doi: 10.1016/j.virol.2013.03.010. Epub 2013 Apr 3. Review.


TLR-9 contributes to the antiviral innate immune sensing of rodent parvoviruses MVMp and H-1PV by normal human immune cells.

Raykov Z, Grekova SP, Hörlein R, Leuchs B, Giese T, Giese NA, Rommelaere J, Zawatzky R, Daeffler L.

PLoS One. 2013;8(1):e55086. doi: 10.1371/journal.pone.0055086. Epub 2013 Jan 29.


DNA recognition in immunity and disease.

Holm CK, Paludan SR, Fitzgerald KA.

Curr Opin Immunol. 2013 Feb;25(1):13-8. doi: 10.1016/j.coi.2012.12.006. Epub 2013 Jan 9. Review.

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