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Notch signaling is significantly suppressed in basal cell carcinomas and activation induces basal cell carcinoma cell apoptosis.

Shi FT, Yu M, Zloty D, Bell RH, Wang E, Akhoundsadegh N, Leung G, Haegert A, Carr N, Shapiro J, McElwee KJ.

Mol Med Rep. 2017 Apr;15(4):1441-1454. doi: 10.3892/mmr.2017.6163. Epub 2017 Feb 2.


Schlafen 4-expressing myeloid-derived suppressor cells are induced during murine gastric metaplasia.

Ding L, Hayes MM, Photenhauer A, Eaton KA, Li Q, Ocadiz-Ruiz R, Merchant JL.

J Clin Invest. 2016 Aug 1;126(8):2867-80. doi: 10.1172/JCI82529. Epub 2016 Jul 18.


Gene Expression Architecture of Mouse Dorsal and Tail Skin Reveals Functional Differences in Inflammation and Cancer.

Quigley DA, Kandyba E, Huang P, Halliwill KD, Sjölund J, Pelorosso F, Wong CE, Hirst GL, Wu D, Delrosario R, Kumar A, Balmain A.

Cell Rep. 2016 Jul 26;16(4):1153-65. doi: 10.1016/j.celrep.2016.06.061. Epub 2016 Jul 14.


LGR5 expression is controled by IKKα in basal cell carcinoma through activating STAT3 signaling pathway.

Jia J, Shi Y, Yan B, Xiao D, Lai W, Pan Y, Jiang Y, Chen L, Mao C, Zhou J, Xi S, Cao Y, Liu S, Tao Y.

Oncotarget. 2016 May 10;7(19):27280-94. doi: 10.18632/oncotarget.8465.


Invasive mouse gastric adenocarcinomas arising from Lgr5+ stem cells are dependent on crosstalk between the Hedgehog/GLI2 and mTOR pathways.

Syu LJ, Zhao X, Zhang Y, Grachtchouk M, Demitrack E, Ermilov A, Wilbert DM, Zheng X, Kaatz A, Greenson JK, Gumucio DL, Merchant JL, di Magliano MP, Samuelson LC, Dlugosz AA.

Oncotarget. 2016 Mar 1;7(9):10255-70. doi: 10.18632/oncotarget.7182.


Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Reprogramming and Underlies Tumor Heterogeneity.

Kretzschmar K, Weber C, Driskell RR, Calonje E, Watt FM.

Cell Rep. 2016 Jan 12;14(2):269-81. doi: 10.1016/j.celrep.2015.12.041. Epub 2016 Jan 7.


Hair Follicle Bulge Stem Cells Appear Dispensable for the Acute Phase of Wound Re-epithelialization.

Garcin CL, Ansell DM, Headon DJ, Paus R, Hardman MJ.

Stem Cells. 2016 May;34(5):1377-85. doi: 10.1002/stem.2289. Epub 2016 Feb 2.


Shh and p50/Bcl3 signaling crosstalk drives pathogenesis of BCCs in Gorlin syndrome.

Chaudhary SC, Tang X, Arumugam A, Li C, Srivastava RK, Weng Z, Xu J, Zhang X, Kim AL, McKay K, Elmets CA, Kopelovich L, Bickers DR, Athar M.

Oncotarget. 2015 Nov 3;6(34):36789-814. doi: 10.18632/oncotarget.5103.


Basal cell carcinoma: pathogenesis, epidemiology, clinical features, diagnosis, histopathology, and management.

Marzuka AG, Book SE.

Yale J Biol Med. 2015 Jun 1;88(2):167-79. eCollection 2015 Jun. Review.


Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin.

Martincorena I, Roshan A, Gerstung M, Ellis P, Van Loo P, McLaren S, Wedge DC, Fullam A, Alexandrov LB, Tubio JM, Stebbings L, Menzies A, Widaa S, Stratton MR, Jones PH, Campbell PJ.

Science. 2015 May 22;348(6237):880-6. doi: 10.1126/science.aaa6806.


Basal cell carcinoma preferentially arises from stem cells within hair follicle and mechanosensory niches.

Peterson SC, Eberl M, Vagnozzi AN, Belkadi A, Veniaminova NA, Verhaegen ME, Bichakjian CK, Ward NL, Dlugosz AA, Wong SY.

Cell Stem Cell. 2015 Apr 2;16(4):400-12. doi: 10.1016/j.stem.2015.02.006.


Developing and regenerating a sense of taste.

Barlow LA, Klein OD.

Curr Top Dev Biol. 2015;111:401-19. doi: 10.1016/bs.ctdb.2014.11.012. Epub 2015 Jan 20. Review.


Interfering with stem cell-specific gatekeeper functions controls tumour initiation and malignant progression of skin tumours.

Petersson M, Reuter K, Brylka H, Kraus A, Schettina P, Niemann C.

Nat Commun. 2015 Jan 22;6:5874. doi: 10.1038/ncomms6874.


Immune status, strain background, and anatomic site of inoculation affect mouse papillomavirus (MmuPV1) induction of exophytic papillomas or endophytic trichoblastomas.

Sundberg JP, Stearns TM, Joh J, Proctor M, Ingle A, Silva KA, Dadras SS, Jenson AB, Ghim SJ.

PLoS One. 2014 Dec 4;9(12):e113582. doi: 10.1371/journal.pone.0113582. eCollection 2014.


Sites of Basal cell carcinomas and head and neck congenital clefts: topographic correlation.

Nicoletti G, Brenta F, Malovini A, Jaber O, Faga A.

Plast Reconstr Surg Glob Open. 2014 Jul 9;2(6):e164. doi: 10.1097/GOX.0000000000000119. eCollection 2014 Jun.


Refining the role for adult stem cells as cancer cells of origin.

White AC, Lowry WE.

Trends Cell Biol. 2015 Jan;25(1):11-20. doi: 10.1016/j.tcb.2014.08.008. Epub 2014 Sep 18. Review.


Sonic hedgehog signaling in Basal cell nevus syndrome.

Athar M, Li C, Kim AL, Spiegelman VS, Bickers DR.

Cancer Res. 2014 Sep 15;74(18):4967-75. doi: 10.1158/0008-5472.CAN-14-1666. Epub 2014 Aug 29. Review.


Horrifying Basal cell carcinoma: cytological, immunohistochemical, and ultrastructural findings.

Kinoshita Y, Takasu K, Yoshizawa K, Emoto Y, Yuki M, Yuri T, Shikata N, Tsubura A.

Case Rep Oncol. 2014 Jul 11;7(2):459-64. doi: 10.1159/000365322. eCollection 2014 May.


Proliferative and non-proliferative lesions of the rat and mouse integument.

Mecklenburg L, Kusewitt D, Kolly C, Treumann S, Adams ET, Diegel K, Yamate J, Kaufmann W, Müller S, Danilenko D, Bradley A.

J Toxicol Pathol. 2013;26(3 Suppl):27S-57S. doi: 10.1293/tox.26.27S. Review.


Advanced treatment for basal cell carcinomas.

Atwood SX, Whitson RJ, Oro AE.

Cold Spring Harb Perspect Med. 2014 Jul 1;4(7):a013581. doi: 10.1101/cshperspect.a013581. Review.

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