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Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS): An Interplay among Drugs, Viruses, and Immune System.

Cho YT, Yang CW, Chu CY.

Int J Mol Sci. 2017 Jun 9;18(6). pii: E1243. doi: 10.3390/ijms18061243. Review.


Severe Delayed Cutaneous and Systemic Reactions to Drugs: A Global Perspective on the Science and Art of Current Practice.

Peter JG, Lehloenya R, Dlamini S, Risma K, White KD, Konvinse KC, Phillips EJ.

J Allergy Clin Immunol Pract. 2017 May - Jun;5(3):547-563. doi: 10.1016/j.jaip.2017.01.025.


Multiphenotype association study of patients randomized to initiate antiretroviral regimens in AIDS Clinical Trials Group protocol A5202.

Verma A, Bradford Y, Verma SS, Pendergrass SA, Daar ES, Venuto C, Morse GD, Ritchie MD, Haas DW.

Pharmacogenet Genomics. 2017 Mar;27(3):101-111. doi: 10.1097/FPC.0000000000000263.


Genome-wide association study of nevirapine hypersensitivity in a sub-Saharan African HIV-infected population.

Carr DF, Bourgeois S, Chaponda M, Takeshita LY, Morris AP, Castro EM, Alfirevic A, Jones AR, Rigden DJ, Haldenby S, Khoo S, Lalloo DG, Heyderman RS, Dandara C, Kampira E, van Oosterhout JJ, Ssali F, Munderi P, Novelli G, Borgiani P, Nelson MR, Holden A, Deloukas P, Pirmohamed M.

J Antimicrob Chemother. 2017 Apr 1;72(4):1152-1162. doi: 10.1093/jac/dkw545.


Are Polymorphisms in Genes Relevant to Drug Disposition Predictors of Susceptibility to Drug-Induced Liver Injury?

Daly AK.

Pharm Res. 2017 Aug;34(8):1564-1569. doi: 10.1007/s11095-016-2091-1. Epub 2016 Dec 27.


Old dog begging for new tricks: current practices and future directions in the diagnosis of delayed antimicrobial hypersensitivity.

Konvinse KC, Phillips EJ, White KD, Trubiano JA.

Curr Opin Infect Dis. 2016 Dec;29(6):561-576.


Individualization of antiretroviral therapy--pharmacogenomic aspect.

Dalal B, Shankarkumar A, Ghosh K.

Indian J Med Res. 2015 Dec;142(6):663-74. doi: 10.4103/0971-5916.174549. Review.


Classifying ADRs--does dose matter?

Phillips EJ.

Br J Clin Pharmacol. 2016 Jan;81(1):10-2. doi: 10.1111/bcp.12749. Epub 2015 Nov 2. No abstract available.


Report from the National Institute of Allergy and Infectious Diseases workshop on drug allergy.

Wheatley LM, Plaut M, Schwaninger JM, Banerji A, Castells M, Finkelman FD, Gleich GJ, Guttman-Yassky E, Mallal SA, Naisbitt DJ, Ostrov DA, Phillips EJ, Pichler WJ, Platts-Mills TA, Roujeau JC, Schwartz LB, Trepanier LA.

J Allergy Clin Immunol. 2015 Aug;136(2):262-71.e2. doi: 10.1016/j.jaci.2015.05.027.


Evolving models of the immunopathogenesis of T cell-mediated drug allergy: The role of host, pathogens, and drug response.

White KD, Chung WH, Hung SI, Mallal S, Phillips EJ.

J Allergy Clin Immunol. 2015 Aug;136(2):219-34; quiz 235. doi: 10.1016/j.jaci.2015.05.050. Review.


Phenome-wide Association Study Relating Pretreatment Laboratory Parameters With Human Genetic Variants in AIDS Clinical Trials Group Protocols.

Moore CB, Verma A, Pendergrass S, Verma SS, Johnson DH, Daar ES, Gulick RM, Haubrich R, Robbins GK, Ritchie MD, Haas DW.

Open Forum Infect Dis. 2015 Jan 9;2(1):ofu113. doi: 10.1093/ofid/ofu113. eCollection 2015 Jan.


Perspectives on pharmacogenomics of antiretroviral medications and HIV-associated comorbidities.

Haas DW, Tarr PE.

Curr Opin HIV AIDS. 2015 Mar;10(2):116-22. doi: 10.1097/COH.0000000000000134. Review.


Pharmacogenomics of antimicrobial agents.

Aung AK, Haas DW, Hulgan T, Phillips EJ.

Pharmacogenomics. 2014;15(15):1903-30. doi: 10.2217/pgs.14.147. Review.


T cell-mediated hypersensitivity reactions to drugs.

Pavlos R, Mallal S, Ostrov D, Buus S, Metushi I, Peters B, Phillips E.

Annu Rev Med. 2015;66:439-54. doi: 10.1146/annurev-med-050913-022745. Epub 2014 Oct 27. Review.


CYP2B6 c.983T>C polymorphism is associated with nevirapine hypersensitivity in Malawian and Ugandan HIV populations.

Carr DF, Chaponda M, Cornejo Castro EM, Jorgensen AL, Khoo S, Van Oosterhout JJ, Dandara C, Kampira E, Ssali F, Munderi P, Lalloo DG, Heyderman RS, Pirmohamed M.

J Antimicrob Chemother. 2014 Dec;69(12):3329-34. doi: 10.1093/jac/dku315. Epub 2014 Aug 20.


Antiviral drug allergy.

Milpied-Homsi B, Moran EM, Phillips EJ.

Immunol Allergy Clin North Am. 2014 Aug;34(3):645-62, ix. doi: 10.1016/j.iac.2014.04.011. Review.


The G⁵¹⁶T CYP2B6 germline polymorphism affects the risk of acute myeloid leukemia and is associated with specific chromosomal abnormalities.

Daraki A, Zachaki S, Koromila T, Diamantopoulou P, Pantelias GE, Sambani C, Aleporou V, Kollia P, Manola KN.

PLoS One. 2014 Feb 24;9(2):e88879. doi: 10.1371/journal.pone.0088879. eCollection 2014.


Fever, rash, and systemic symptoms: understanding the role of virus and HLA in severe cutaneous drug allergy.

Pavlos R, Mallal S, Ostrov D, Pompeu Y, Phillips E.

J Allergy Clin Immunol Pract. 2014 Jan-Feb;2(1):21-33. doi: 10.1016/j.jaip.2013.11.005. Review.


Genotyping for severe drug hypersensitivity.

Karlin E, Phillips E.

Curr Allergy Asthma Rep. 2014 Mar;14(3):418. doi: 10.1007/s11882-013-0418-0. Review.


Cytotoxic proteins and therapeutic targets in severe cutaneous adverse reactions.

Su SC, Chung WH.

Toxins (Basel). 2014 Jan 3;6(1):194-210. doi: 10.3390/toxins6010194. Review.

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