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Items: 1 to 20 of 25

1.

The pattern of hMENA isoforms is regulated by TGF-β1 in pancreatic cancer and may predict patient outcome.

Melchionna R, Iapicca P, Di Modugno F, Trono P, Sperduti I, Fassan M, Cataldo I, Rusev BC, Lawlor RT, Diodoro MG, Milella M, Grazi GL, Bissell MJ, Scarpa A, Nisticò P.

Oncoimmunology. 2016 Aug 12;5(12):e1221556. doi: 10.1080/2162402X.2016.1221556.

2.

Macrophage-dependent tumor cell transendothelial migration is mediated by Notch1/MenaINV-initiated invadopodium formation.

Pignatelli J, Bravo-Cordero JJ, Roh-Johnson M, Gandhi SJ, Wang Y, Chen X, Eddy RJ, Xue A, Singer RH, Hodgson L, Oktay MH, Condeelis JS.

Sci Rep. 2016 Nov 30;6:37874. doi: 10.1038/srep37874.

3.

MenaINV dysregulates cortactin phosphorylation to promote invadopodium maturation.

Weidmann MD, Surve CR, Eddy RJ, Chen X, Gertler FB, Sharma VP, Condeelis JS.

Sci Rep. 2016 Nov 8;6:36142. doi: 10.1038/srep36142.

4.

The alternatively-included 11a sequence modifies the effects of Mena on actin cytoskeletal organization and cell behavior.

Balsamo M, Mondal C, Carmona G, McClain LM, Riquelme DN, Tadros J, Ma D, Vasile E, Condeelis JS, Lauffenburger DA, Gertler FB.

Sci Rep. 2016 Oct 17;6:35298. doi: 10.1038/srep35298.

5.

Signatures of breast cancer metastasis at a glance.

Karagiannis GS, Goswami S, Jones JG, Oktay MH, Condeelis JS.

J Cell Sci. 2016 May 1;129(9):1751-8. doi: 10.1242/jcs.183129. Review.

6.

3-D individual cell based computational modeling of tumor cell-macrophage paracrine signaling mediated by EGF and CSF-1 gradients.

Knutsdottir H, Condeelis JS, Palsson E.

Integr Biol (Camb). 2016 Jan;8(1):104-19. doi: 10.1039/c5ib00201j.

7.

Characterization of the expression of the pro-metastatic Mena(INV) isoform during breast tumor progression.

Oudin MJ, Hughes SK, Rohani N, Moufarrej MN, Jones JG, Condeelis JS, Lauffenburger DA, Gertler FB.

Clin Exp Metastasis. 2016 Mar;33(3):249-61. doi: 10.1007/s10585-015-9775-5.

PMID:
26680363
8.

PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena.

Hughes SK, Oudin MJ, Tadros J, Neil J, Del Rosario A, Joughin BA, Ritsma L, Wyckoff J, Vasile E, Eddy R, Philippar U, Lussiez A, Condeelis JS, van Rheenen J, White F, Lauffenburger DA, Gertler FB.

Mol Biol Cell. 2015 Nov 1;26(21):3867-78. doi: 10.1091/mbc.E15-06-0442.

9.

Perivascular M2 Macrophages Stimulate Tumor Relapse after Chemotherapy.

Hughes R, Qian BZ, Rowan C, Muthana M, Keklikoglou I, Olson OC, Tazzyman S, Danson S, Addison C, Clemons M, Gonzalez-Angulo AM, Joyce JA, De Palma M, Pollard JW, Lewis CE.

Cancer Res. 2015 Sep 1;75(17):3479-91. doi: 10.1158/0008-5472.CAN-14-3587.

10.

Selectivity in subunit composition of Ena/VASP tetramers.

Riquelme DN, Meyer AS, Barzik M, Keating A, Gertler FB.

Biosci Rep. 2015 Jul 28;35(5). pii: e00246. doi: 10.1042/BSR20150149.

11.

Menacalc, a quantitative method of metastasis assessment, as a prognostic marker for axillary node-negative breast cancer.

Forse CL, Agarwal S, Pinnaduwage D, Gertler F, Condeelis JS, Lin J, Xue X, Johung K, Mulligan AM, Rohan TE, Bull SB, Andrulis IL.

BMC Cancer. 2015 Jun 27;15:483. doi: 10.1186/s12885-015-1468-6.

12.

Invasive breast carcinoma cells from patients exhibit MenaINV- and macrophage-dependent transendothelial migration.

Pignatelli J, Goswami S, Jones JG, Rohan TE, Pieri E, Chen X, Adler E, Cox D, Maleki S, Bresnick A, Gertler FB, Condeelis JS, Oktay MH.

Sci Signal. 2014 Nov 25;7(353):ra112. doi: 10.1126/scisignal.2005329.

13.

Tumor microenvironment of metastasis and risk of distant metastasis of breast cancer.

Rohan TE, Xue X, Lin HM, D'Alfonso TM, Ginter PS, Oktay MH, Robinson BD, Ginsberg M, Gertler FB, Glass AG, Sparano JA, Condeelis JS, Jones JG.

J Natl Cancer Inst. 2014 Jun 3;106(8). pii: dju136. doi: 10.1093/jnci/dju136.

14.

Traversing the basement membrane in vivo: a diversity of strategies.

Kelley LC, Lohmer LL, Hagedorn EJ, Sherwood DR.

J Cell Biol. 2014 Feb 3;204(3):291-302. doi: 10.1083/jcb.201311112. Review.

15.

Autocrine HBEGF expression promotes breast cancer intravasation, metastasis and macrophage-independent invasion in vivo.

Zhou ZN, Sharma VP, Beaty BT, Roh-Johnson M, Peterson EA, Van Rooijen N, Kenny PA, Wiley HS, Condeelis JS, Segall JE.

Oncogene. 2014 Jul 17;33(29):3784-93. doi: 10.1038/onc.2013.363.

16.

Imaging interactions between macrophages and tumour cells that are involved in metastasis in vivo and in vitro.

Dovas A, Patsialou A, Harney AS, Condeelis J, Cox D.

J Microsc. 2013 Sep;251(3):261-9. doi: 10.1111/j.1365-2818.2012.03667.x. Review.

17.

Splicing program of human MENA produces a previously undescribed isoform associated with invasive, mesenchymal-like breast tumors.

Di Modugno F, Iapicca P, Boudreau A, Mottolese M, Terrenato I, Perracchio L, Carstens RP, Santoni A, Bissell MJ, Nisticò P.

Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19280-5. doi: 10.1073/pnas.1214394109.

18.

Molecular insights on context-specific role of profilin-1 in cell migration.

Ding Z, Bae YH, Roy P.

Cell Adh Migr. 2012 Sep-Oct;6(5):442-9. doi: 10.4161/cam.21832. Review.

19.

Quantitative assessment of invasive mena isoforms (Menacalc) as an independent prognostic marker in breast cancer.

Agarwal S, Gertler FB, Balsamo M, Condeelis JS, Camp RL, Xue X, Lin J, Rohan TE, Rimm DL.

Breast Cancer Res. 2012 Sep 12;14(5):R124. doi: 10.1186/bcr3318.

20.

Mena binds α5 integrin directly and modulates α5β1 function.

Gupton SL, Riquelme D, Hughes-Alford SK, Tadros J, Rudina SS, Hynes RO, Lauffenburger D, Gertler FB.

J Cell Biol. 2012 Aug 20;198(4):657-76. doi: 10.1083/jcb.201202079.

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