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Items: 1 to 20 of 39

1.

The Role of Conformational Dynamics in Antigen Trimming by Intracellular Aminopeptidases.

Papakyriakou A, Stratikos E.

Front Immunol. 2017 Aug 7;8:946. doi: 10.3389/fimmu.2017.00946. eCollection 2017. Review.

2.

The interplay between HLA-B27 and ERAP1/ERAP2 aminopeptidases: from anti-viral protection to spondyloarthritis.

Vitulano C, Tedeschi V, Paladini F, Sorrentino R, Fiorillo MT.

Clin Exp Immunol. 2017 Dec;190(3):281-290. doi: 10.1111/cei.13020. Epub 2017 Aug 30. Review.

PMID:
28759104
3.

Allosteric inhibition of aminopeptidase N functions related to tumor growth and virus infection.

Santiago C, Mudgal G, Reguera J, Recacha R, Albrecht S, Enjuanes L, Casasnovas JM.

Sci Rep. 2017 Apr 10;7:46045. doi: 10.1038/srep46045.

4.

Structural basis of pH-dependent client binding by ERp44, a key regulator of protein secretion at the ER-Golgi interface.

Watanabe S, Harayama M, Kanemura S, Sitia R, Inaba K.

Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):E3224-E3232. doi: 10.1073/pnas.1621426114. Epub 2017 Apr 3.

5.

Role of HLA-B27 in the pathogenesis of ankylosing spondylitis (Review).

Chen B, Li J, He C, Li D, Tong W, Zou Y, Xu W.

Mol Med Rep. 2017 Apr;15(4):1943-1951. doi: 10.3892/mmr.2017.6248. Epub 2017 Feb 24. Review.

6.

The Human Leukocyte Antigen (HLA)-B27 Peptidome in Vivo, in Spondyloarthritis-susceptible HLA-B27 Transgenic Rats and the Effect of Erap1 Deletion.

Barnea E, Melamed Kadosh D, Haimovich Y, Satumtira N, Dorris ML, Nguyen MT, Hammer RE, Tran TM, Colbert RA, Taurog JD, Admon A.

Mol Cell Proteomics. 2017 Apr;16(4):642-662. doi: 10.1074/mcp.M116.066241. Epub 2017 Feb 10.

PMID:
28188227
7.

Crystal structure of a polypeptide's C-terminus in complex with the regulatory domain of ER aminopeptidase 1.

Sui L, Gandhi A, Guo HC.

Mol Immunol. 2016 Dec;80:41-49. doi: 10.1016/j.molimm.2016.10.012. Epub 2016 Nov 5.

8.

Present Yourself! By MHC Class I and MHC Class II Molecules.

Rock KL, Reits E, Neefjes J.

Trends Immunol. 2016 Nov;37(11):724-737. doi: 10.1016/j.it.2016.08.010. Epub 2016 Sep 7. Review.

9.

ERAP1-ERAP2 dimers trim MHC I-bound precursor peptides; implications for understanding peptide editing.

Chen H, Li L, Weimershaus M, Evnouchidou I, van Endert P, Bouvier M.

Sci Rep. 2016 Aug 12;6:28902. doi: 10.1038/srep28902.

10.

Screening Identifies Thimerosal as a Selective Inhibitor of Endoplasmic Reticulum Aminopeptidase 1.

Stamogiannos A, Papakyriakou A, Mauvais FX, van Endert P, Stratikos E.

ACS Med Chem Lett. 2016 May 31;7(7):681-5. doi: 10.1021/acsmedchemlett.6b00084. eCollection 2016 Jul 14.

11.

Structural Basis for Antigenic Peptide Recognition and Processing by Endoplasmic Reticulum (ER) Aminopeptidase 2.

Mpakali A, Giastas P, Mathioudakis N, Mavridis IM, Saridakis E, Stratikos E.

J Biol Chem. 2015 Oct 23;290(43):26021-32. doi: 10.1074/jbc.M115.685909. Epub 2015 Sep 17.

12.

The Anopheles-midgut APN1 structure reveals a new malaria transmission-blocking vaccine epitope.

Atkinson SC, Armistead JS, Mathias DK, Sandeu MM, Tao D, Borhani-Dizaji N, Tarimo BB, Morlais I, Dinglasan RR, Borg NA.

Nat Struct Mol Biol. 2015 Jul;22(7):532-9. doi: 10.1038/nsmb.3048. Epub 2015 Jun 15.

13.

Endoplasmic Reticulum Aminopeptidase 1 (ERAP1) Polymorphism Relevant to Inflammatory Disease Shapes the Peptidome of the Birdshot Chorioretinopathy-Associated HLA-A*29:02 Antigen.

Alvarez-Navarro C, Martín-Esteban A, Barnea E, Admon A, López de Castro JA.

Mol Cell Proteomics. 2015 Jul;14(7):1770-80. doi: 10.1074/mcp.M115.048959. Epub 2015 Apr 19.

14.

Autoimmune disease-associated variants of extracellular endoplasmic reticulum aminopeptidase 1 induce altered innate immune responses by human immune cells.

Aldhamen YA, Pepelyayeva Y, Rastall DP, Seregin SS, Zervoudi E, Koumantou D, Aylsworth CF, Quiroga D, Godbehere S, Georgiadis D, Stratikos E, Amalfitano A.

J Innate Immun. 2015;7(3):275-89. doi: 10.1159/000368899. Epub 2015 Jan 14.

15.

A role for naturally occurring alleles of endoplasmic reticulum aminopeptidases in tumor immunity and cancer pre-disposition.

Stratikos E, Stamogiannos A, Zervoudi E, Fruci D.

Front Oncol. 2014 Dec 19;4:363. doi: 10.3389/fonc.2014.00363. eCollection 2014. Review.

16.
17.

Functionally distinct ERAP1 allotype combinations distinguish individuals with Ankylosing Spondylitis.

Reeves E, Colebatch-Bourn A, Elliott T, Edwards CJ, James E.

Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):17594-9. doi: 10.1073/pnas.1408882111. Epub 2014 Nov 24.

18.

Crystal structure of human insulin-regulated aminopeptidase with specificity for cyclic peptides.

Hermans SJ, Ascher DB, Hancock NC, Holien JK, Michell BJ, Chai SY, Morton CJ, Parker MW.

Protein Sci. 2015 Feb;24(2):190-9. doi: 10.1002/pro.2604. Epub 2014 Dec 26.

19.

Modeling of human M1 aminopeptidases for in silico screening of potential Plasmodium falciparum alanine aminopeptidase (PfA-M1) specific inhibitors.

Sahi S, Rai S, Chaudhary M, Nain V.

Bioinformation. 2014 Aug 30;10(8):518-25. doi: 10.6026/97320630010518. eCollection 2014.

20.

ERAP1 functions override the intrinsic selection of specific antigens as immunodominant peptides, thereby altering the potency of antigen-specific cytolytic and effector memory T-cell responses.

Rastall DP, Aldhamen YA, Seregin SS, Godbehere S, Amalfitano A.

Int Immunol. 2014 Dec;26(12):685-95. doi: 10.1093/intimm/dxu078. Epub 2014 Aug 2.

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