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A GAP that Divides.

Basant A, Glotzer M.

F1000Res. 2017 Oct 2;6:1788. doi: 10.12688/f1000research.12064.1. eCollection 2017. Review.


Deletion of RhoA in Progesterone Receptor-Expressing Cells Leads to Luteal Insufficiency and Infertility in Female Mice.

El Zowalaty AE, Li R, Zheng Y, Lydon JP, DeMayo FJ, Ye X.

Endocrinology. 2017 Jul 1;158(7):2168-2178. doi: 10.1210/en.2016-1796.


Links between DNA Replication, Stem Cells and Cancer.

Vassilev A, DePamphilis ML.

Genes (Basel). 2017 Jan 25;8(2). pii: E45. doi: 10.3390/genes8020045. Review.


LPA Induces Colon Cancer Cell Proliferation through a Cooperation between the ROCK and STAT-3 Pathways.

Leve F, Peres-Moreira RJ, Binato R, Abdelhay E, Morgado-Díaz JA.

PLoS One. 2015 Sep 29;10(9):e0139094. doi: 10.1371/journal.pone.0139094. eCollection 2015.


Cytokinesis failure in RhoA-deficient mouse erythroblasts involves actomyosin and midbody dysregulation and triggers p53 activation.

Konstantinidis DG, Giger KM, Risinger M, Pushkaran S, Zhou P, Dexheimer P, Yerneni S, Andreassen P, Klingmüller U, Palis J, Zheng Y, Kalfa TA.

Blood. 2015 Sep 17;126(12):1473-82. doi: 10.1182/blood-2014-12-616169. Epub 2015 Jul 30.


Physical view on migration modes.

Mierke CT.

Cell Adh Migr. 2015;9(5):367-79. doi: 10.1080/19336918.2015.1066958. Review.


RhoC maintains vascular homeostasis by regulating VEGF-induced signaling in endothelial cells.

Hoeppner LH, Sinha S, Wang Y, Bhattacharya R, Dutta S, Gong X, Bedell VM, Suresh S, Chun C, Ramchandran R, Ekker SC, Mukhopadhyay D.

J Cell Sci. 2015 Oct 1;128(19):3556-68. doi: 10.1242/jcs.167601. Epub 2015 Jul 1.


RhoA orchestrates glycolysis for TH2 cell differentiation and allergic airway inflammation.

Yang JQ, Kalim KW, Li Y, Zhang S, Hinge A, Filippi MD, Zheng Y, Guo F.

J Allergy Clin Immunol. 2016 Jan;137(1):231-245.e4. doi: 10.1016/j.jaci.2015.05.004. Epub 2015 Jun 19.


Loss of RhoA Exacerbates, Rather Than Dampens, Oncogenic K-Ras Induced Lung Adenoma Formation in Mice.

Zandvakili I, Davis AK, Hu G, Zheng Y.

PLoS One. 2015 Jun 1;10(6):e0127923. doi: 10.1371/journal.pone.0127923. eCollection 2015.


RhoA and ROCK mediate histamine-induced vascular leakage and anaphylactic shock.

Mikelis CM, Simaan M, Ando K, Fukuhara S, Sakurai A, Amornphimoltham P, Masedunskas A, Weigert R, Chavakis T, Adams RH, Offermanns S, Mochizuki N, Zheng Y, Gutkind JS.

Nat Commun. 2015 Apr 10;6:6725. doi: 10.1038/ncomms7725.


Rhof promotes murine marginal zone B cell development.

Kishimoto M, Matsuda T, Yanase S, Katsumi A, Suzuki N, Ikejiri M, Takagi A, Ikawa M, Kojima T, Kunishima S, Kiyoi H, Naoe T, Matsushita T, Maruyama M.

Nagoya J Med Sci. 2014 Aug;76(3-4):293-305.


Gene targeting RhoA reveals its essential role in coordinating mitochondrial function and thymocyte development.

Zhang S, Konstantinidis DG, Yang JQ, Mizukawa B, Kalim K, Lang RA, Kalfa TA, Zheng Y, Guo F.

J Immunol. 2014 Dec 15;193(12):5973-82. doi: 10.4049/jimmunol.1400839. Epub 2014 Nov 14.


Mouse macrophages completely lacking Rho subfamily GTPases (RhoA, RhoB, and RhoC) have severe lamellipodial retraction defects, but robust chemotactic navigation and altered motility.

Königs V, Jennings R, Vogl T, Horsthemke M, Bachg AC, Xu Y, Grobe K, Brakebusch C, Schwab A, Bähler M, Knaus UG, Hanley PJ.

J Biol Chem. 2014 Oct 31;289(44):30772-84. doi: 10.1074/jbc.M114.563270. Epub 2014 Sep 11.


Rho GTPases: masters of cell migration.

Sadok A, Marshall CJ.

Small GTPases. 2014;5:e29710. doi: 10.4161/sgtp.29710. Epub 2014 Jun 30. Review.


The PI3K/Akt signaling pathway exerts effects on the implantation of mouse embryos by regulating the expression of RhoA.

Liu L, Wang Y, Yu Q.

Int J Mol Med. 2014 May;33(5):1089-96. doi: 10.3892/ijmm.2014.1701. Epub 2014 Mar 17.


Rho, nuclear actin, and actin-binding proteins in the regulation of transcription and gene expression.

Rajakylä EK, Vartiainen MK.

Small GTPases. 2014;5:e27539. doi: 10.4161/sgtp.27539. Epub 2014 Mar 6. Review.


A RhoC biosensor reveals differences in the activation kinetics of RhoA and RhoC in migrating cells.

Zawistowski JS, Sabouri-Ghomi M, Danuser G, Hahn KM, Hodgson L.

PLoS One. 2013 Nov 5;8(11):e79877. doi: 10.1371/journal.pone.0079877. eCollection 2013.


Cell type-specific signaling function of RhoA GTPase: lessons from mouse gene targeting.

Zhou X, Zheng Y.

J Biol Chem. 2013 Dec 20;288(51):36179-88. doi: 10.1074/jbc.R113.515486. Epub 2013 Nov 7. Review.


RhoA GTPase controls cytokinesis and programmed necrosis of hematopoietic progenitors.

Zhou X, Florian MC, Arumugam P, Chen X, Cancelas JA, Lang R, Malik P, Geiger H, Zheng Y.

J Exp Med. 2013 Oct 21;210(11):2371-85. doi: 10.1084/jem.20122348. Epub 2013 Oct 7.


RhoA and Cdc42 are required in pre-migratory progenitors of the medial ganglionic eminence ventricular zone for proper cortical interneuron migration.

Katayama K, Imai F, Campbell K, Lang RA, Zheng Y, Yoshida Y.

Development. 2013 Aug;140(15):3139-45. doi: 10.1242/dev.092585.

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