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In vitro downregulated hypoxia transcriptome is associated with poor prognosis in breast cancer.

Abu-Jamous B, Buffa FM, Harris AL, Nandi AK.

Mol Cancer. 2017 Jun 15;16(1):105. doi: 10.1186/s12943-017-0673-0.


Hypoxia-inducible factor 1 alpha is a poor prognostic factor and potential therapeutic target in malignant peripheral nerve sheath tumor.

Fukushima S, Endo M, Matsumoto Y, Fukushi JI, Matsunobu T, Kawaguchi KI, Setsu N, IIda K, Yokoyama N, Nakagawa M, Yahiro K, Oda Y, Iwamoto Y, Nakashima Y.

PLoS One. 2017 May 30;12(5):e0178064. doi: 10.1371/journal.pone.0178064. eCollection 2017.


Cardiopulmonary phenotype associated with human PHD2 mutation.

Talbot NP, Smith TG, Balanos GM, Dorrington KL, Maxwell PH, Robbins PA.

Physiol Rep. 2017 Apr;5(7). pii: e13224. doi: 10.14814/phy2.13224.


Update on hypoxia-inducible factors and hydroxylases in oxygen regulatory pathways: from physiology to therapeutics.

Ratcliffe P, Koivunen P, Myllyharju J, Ragoussis J, Bovée JV, Batinic-Haberle I, Vinatier C, Trichet V, Robriquet F, Oliver L, Gardie B.

Hypoxia (Auckl). 2017 Mar 15;5:11-20. doi: 10.2147/HP.S127042. eCollection 2017. Review.


Mitochondrial composition and function under the control of hypoxia.

Fuhrmann DC, Brüne B.

Redox Biol. 2017 Aug;12:208-215. doi: 10.1016/j.redox.2017.02.012. Epub 2017 Feb 24. Review.


Induction of Syndecan-4 by Organic-Inorganic Hybrid Molecules with a 1,10-Phenanthroline Structure in Cultured Vascular Endothelial Cells.

Hara T, Kojima T, Matsuzaki H, Nakamura T, Yoshida E, Fujiwara Y, Yamamoto C, Saito S, Kaji T.

Int J Mol Sci. 2017 Feb 8;18(2). pii: E352. doi: 10.3390/ijms18020352.


The expression of the BPIFB4 and CXCR4 associates with sustained health in long-living individuals from Cilento-Italy.

Spinetti G, Sangalli E, Specchia C, Villa F, Spinelli C, Pipolo R, Carrizzo A, Greco S, Voellenkle C, Vecchione C, Madeddu P, Martelli F, Puca AA.

Aging (Albany NY). 2017 Jan 22;9(2):370-380. doi: 10.18632/aging.101159.


Hypoxia-Induced Fibroblast Growth Factor 11 Stimulates Osteoclast-Mediated Resorption of Bone.

Knowles HJ.

Calcif Tissue Int. 2017 Apr;100(4):382-391. doi: 10.1007/s00223-016-0228-1. Epub 2017 Jan 18.


Down-Regulation of EPAS1 Transcription and Genetic Adaptation of Tibetans to High-Altitude Hypoxia.

Peng Y, Cui C, He Y, Ouzhuluobu, Zhang H, Yang D, Zhang Q, Bianbazhuoma, Yang L, He Y, Xiang K, Zhang X, Bhandari S, Shi P, Yangla, Dejiquzong, Baimakangzhuo, Duojizhuoma, Pan Y, Cirenyangji, Baimayangji, Gonggalanzi, Bai C, Bianba, Basang, Ciwangsangbu, Xu S, Chen H, Liu S, Wu T, Qi X, Su B.

Mol Biol Evol. 2017 Apr 1;34(4):818-830. doi: 10.1093/molbev/msw280.


Analysis of the FGF gene family provides insights into aquatic adaptation in cetaceans.

Nam K, Lee KW, Chung O, Yim HS, Cha SS, Lee SW, Jun J, Cho YS, Bhak J, Magalhães JP, Lee JH, Jeong JY.

Sci Rep. 2017 Jan 11;7:40233. doi: 10.1038/srep40233.


Hypoxia and cellular metabolism in tumour pathophysiology.

Parks SK, Cormerais Y, Pouysségur J.

J Physiol. 2017 Apr 15;595(8):2439-2450. doi: 10.1113/JP273309. Epub 2017 Feb 19.


A genetically encoded biosensor for visualising hypoxia responses in vivo.

Misra T, Baccino-Calace M, Meyenhofer F, Rodriguez-Crespo D, Akarsu H, Armenta-Calderón R, Gorr TA, Frei C, Cantera R, Egger B, Luschnig S.

Biol Open. 2017 Feb 15;6(2):296-304. doi: 10.1242/bio.018226.


Genome-Wide STAT3 Binding Analysis after Histone Deacetylase Inhibition Reveals Novel Target Genes in Dendritic Cells.

Sun Y, Iyer M, McEachin R, Zhao M, Wu YM, Cao X, Oravecz-Wilson K, Zajac C, Mathewson N, Wu SJ, Rossi C, Toubai T, Qin ZS, Chinnaiyan AM, Reddy P.

J Innate Immun. 2017;9(2):126-144. doi: 10.1159/000450681. Epub 2016 Nov 19.


HIF-KDM3A-MMP12 regulatory circuit ensures trophoblast plasticity and placental adaptations to hypoxia.

Chakraborty D, Cui W, Rosario GX, Scott RL, Dhakal P, Renaud SJ, Tachibana M, Rumi MA, Mason CW, Krieg AJ, Soares MJ.

Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):E7212-E7221. Epub 2016 Nov 2.


PHD2: from hypoxia regulation to disease progression.

Meneses AM, Wielockx B.

Hypoxia (Auckl). 2016 Apr 11;4:53-67. eCollection 2016. Review.


Forkhead Transcription Factor 3a (FOXO3a) Modulates Hypoxia Signaling via Up-regulation of the von Hippel-Lindau Gene (VHL).

Liu X, Cai X, Hu B, Mei Z, Zhang D, Ouyang G, Wang J, Zhang W, Xiao W.

J Biol Chem. 2016 Dec 2;291(49):25692-25705. Epub 2016 Oct 24.


Genetic variation at the 8q24.21 renal cancer susceptibility locus affects HIF binding to a MYC enhancer.

Grampp S, Platt JL, Lauer V, Salama R, Kranz F, Neumann VK, Wach S, Stöhr C, Hartmann A, Eckardt KU, Ratcliffe PJ, Mole DR, Schödel J.

Nat Commun. 2016 Oct 24;7:13183. doi: 10.1038/ncomms13183.


Signaling hypoxia by hypoxia-inducible factor protein hydroxylases: a historical overview and future perspectives.

Bishop T, Ratcliffe PJ.

Hypoxia (Auckl). 2014 Dec 5;2:197-213. eCollection 2014. Review.


The role of HIFs in ischemia-reperfusion injury.

Howell NJ, Tennant DA.

Hypoxia (Auckl). 2014 Jul 30;2:107-115. eCollection 2014. Review.


Complex role of HIF in cancer: the known, the unknown, and the unexpected.

Tiburcio PD, Choi H, Huang LE.

Hypoxia (Auckl). 2014 Jun 18;2:59-70. eCollection 2014. Review.

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