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Items: 1 to 20 of 112


The asparagine 533 residue in the outer pore loop region of the mouse PKD2L1 channel is essential for its voltage-dependent inactivation.

Shimizu T, Higuchi T, Toba T, Ohno C, Fujii T, Nilius B, Sakai H.

FEBS Open Bio. 2017 Aug 14;7(9):1392-1401. doi: 10.1002/2211-5463.12273. eCollection 2017 Sep.


Novel selective, potent naphthyl TRPM8 antagonists identified through a combined ligand- and structure-based virtual screening approach.

Beccari AR, Gemei M, Monte ML, Menegatti N, Fanton M, Pedretti A, Bovolenta S, Nucci C, Molteni A, Rossignoli A, Brandolini L, Taddei A, Za L, Liberati C, Vistoli G.

Sci Rep. 2017 Sep 8;7(1):10999. doi: 10.1038/s41598-017-11194-0.


Conjugated polymers mediate effective activation of the Mammalian Ion Channel Transient Receptor Potential Vanilloid 1.

Lodola F, Martino N, Tullii G, Lanzani G, Antognazza MR.

Sci Rep. 2017 Aug 16;7(1):8477. doi: 10.1038/s41598-017-08541-6.


Regulatory Mechanisms Controlling Maturation of Serotonin Neuron Identity and Function.

Spencer WC, Deneris ES.

Front Cell Neurosci. 2017 Jul 19;11:215. doi: 10.3389/fncel.2017.00215. eCollection 2017.


Identification of a Novel TRPM8 Agonist from Nutmeg: A Promising Cooling Compound.

Shirai T, Kumihashi K, Sakasai M, Kusuoku H, Shibuya Y, Ohuchi A.

ACS Med Chem Lett. 2017 May 31;8(7):715-719. doi: 10.1021/acsmedchemlett.7b00104. eCollection 2017 Jul 13.


TRPV4 plays a role in breast cancer cell migration via Ca2+-dependent activation of AKT and downregulation of E-cadherin cell cortex protein.

Lee WH, Choong LY, Jin TH, Mon NN, Chong S, Liew CS, Putti T, Lu SY, Harteneck C, Lim YP.

Oncogenesis. 2017 May 22;6(5):e338. doi: 10.1038/oncsis.2017.39.


Characterization of TRPA channels in the starfish Patiria pectinifera: involvement of thermally activated TRPA1 in thermotaxis in marine planktonic larvae.

Saito S, Hamanaka G, Kawai N, Furukawa R, Gojobori J, Tominaga M, Kaneko H, Satta Y.

Sci Rep. 2017 May 19;7(1):2173. doi: 10.1038/s41598-017-02171-8.


Smooth Muscle Ion Channels and Regulation of Vascular Tone in Resistance Arteries and Arterioles.

Tykocki NR, Boerman EM, Jackson WF.

Compr Physiol. 2017 Mar 16;7(2):485-581. doi: 10.1002/cphy.c160011.


Identification and Expression Analysis of the Complete Family of Zebrafish pkd Genes.

England SJ, Campbell PC, Banerjee S, Swanson AJ, Lewis KE.

Front Cell Dev Biol. 2017 Feb 21;5:5. doi: 10.3389/fcell.2017.00005. eCollection 2017.


Inhibition of cyst growth in PCK and Wpk rat models of polycystic kidney disease with low doses of peroxisome proliferator-activated receptor γ agonists.

Flaig SM, Gattone VH, Blazer-Yost BL.

J Transl Int Med. 2016 Sep 1;4(3):118-126. doi: 10.1515/jtim-2016-0028. Epub 2016 Sep 23.


Bilaterian Giant Ankyrins Have a Common Evolutionary Origin and Play a Conserved Role in Patterning the Axon Initial Segment.

Jegla T, Nguyen MM, Feng C, Goetschius DJ, Luna E, van Rossum DB, Kamel B, Pisupati A, Milner ES, Rolls MM.

PLoS Genet. 2016 Dec 2;12(12):e1006457. doi: 10.1371/journal.pgen.1006457. eCollection 2016 Dec.


The N-terminal Ankyrin Repeat Domain Is Not Required for Electrophile and Heat Activation of the Purified Mosquito TRPA1 Receptor.

Survery S, Moparthi L, Kjellbom P, Högestätt ED, Zygmunt PM, Johanson U.

J Biol Chem. 2016 Dec 23;291(52):26899-26912. doi: 10.1074/jbc.M116.743443. Epub 2016 Nov 14.


TRPA1 Channels in Drosophila and Honey Bee Ectoparasitic Mites Share Heat Sensitivity and Temperature-Related Physiological Functions.

Peng G, Kashio M, Li T, Dong X, Tominaga M, Kadowaki T.

Front Physiol. 2016 Oct 5;7:447. eCollection 2016.


Movement deficits and neuronal loss in basal ganglia in TRPC1 deficient mice.

He K, Qi F, Guo C, Zhan S, Xu H, Liu J, Yang X.

Oncotarget. 2016 Oct 25;7(43):69337-69346. doi: 10.18632/oncotarget.12567.


Nicotinamide is an endogenous agonist for a C. elegans TRPV OSM-9 and OCR-4 channel.

Upadhyay A, Pisupati A, Jegla T, Crook M, Mickolajczyk KJ, Shorey M, Rohan LE, Billings KA, Rolls MM, Hancock WO, Hanna-Rose W.

Nat Commun. 2016 Oct 12;7:13135. doi: 10.1038/ncomms13135.


Control of cell mechanics by RhoA and calcium fluxes during epithelial scattering.

Haws HJ, McNeil MA, Hansen MD.

Tissue Barriers. 2016 May 11;4(3):e1187326. doi: 10.1080/21688370.2016.1187326. eCollection 2016 Jul-Sep. Review.


Effects of N-Glycosylation of the human cation channel TRPA1 on agonist-sensitivity.

Egan TJ, Acuña MA, Zenobi-Wong M, Zeilhofer HU, Urech D.

Biosci Rep. 2016 Aug 31. pii: BSR20160149. [Epub ahead of print]


Role of TRP channels in the induction of heat shock proteins (Hsps) by heating skin.

Hsu WL, Yoshioka T.

Biophysics (Nagoya-shi). 2015 Feb 13;11:25-32. doi: 10.2142/biophysics.11.25. eCollection 2015. Review.

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