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A novel technique of serial biopsy in mouse brain tumour models.

Rogers S, Hii H, Huang J, Ancliffe M, Gottardo NG, Dallas P, Lee S, Endersby R.

PLoS One. 2017 Apr 10;12(4):e0175169. doi: 10.1371/journal.pone.0175169. eCollection 2017.


Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures.

Graham NA, Minasyan A, Lomova A, Cass A, Balanis NG, Friedman M, Chan S, Zhao S, Delgado A, Go J, Beck L, Hurtz C, Ng C, Qiao R, Ten Hoeve J, Palaskas N, Wu H, Müschen M, Multani AS, Port E, Larson SM, Schultz N, Braas D, Christofk HR, Mellinghoff IK, Graeber TG.

Mol Syst Biol. 2017 Feb 15;13(2):914. doi: 10.15252/msb.20167159.


Non-tumor cell IDO1 predominantly contributes to enzyme activity and response to CTLA-4/PD-L1 inhibition in mouse glioblastoma.

Zhai L, Ladomersky E, Dostal CR, Lauing KL, Swoap K, Billingham LK, Gritsina G, Wu M, McCusker RH, Binder DC, Wainwright DA.

Brain Behav Immun. 2017 May;62:24-29. doi: 10.1016/j.bbi.2017.01.022. Epub 2017 Feb 4.


Contribution of classical end-joining to PTEN inactivation in p53-mediated glioblastoma formation and drug-resistant survival.

Kang YJ, Balter B, Csizmadia E, Haas B, Sharma H, Bronson R, Yan CT.

Nat Commun. 2017 Jan 17;8:14013. doi: 10.1038/ncomms14013.


Cooperative genomic alteration network reveals molecular classification across 12 major cancer types.

Zhang H, Deng Y, Zhang Y, Ping Y, Zhao H, Pang L, Zhang X, Wang L, Xu C, Xiao Y, Li X.

Nucleic Acids Res. 2017 Jan 25;45(2):567-582. doi: 10.1093/nar/gkw1087. Epub 2016 Nov 29.


Cell of origin of glioma: biological and clinical implications.

Alcantara Llaguno SR, Parada LF.

Br J Cancer. 2016 Dec 6;115(12):1445-1450. doi: 10.1038/bjc.2016.354. Epub 2016 Nov 10.


PTEN Signaling in the Postnatal Perivascular Progenitor Niche Drives Medulloblastoma Formation.

Zhu G, Rankin SL, Larson JD, Zhu X, Chow LM, Qu C, Zhang J, Ellison DW, Baker SJ.

Cancer Res. 2017 Jan 1;77(1):123-133. doi: 10.1158/0008-5472.CAN-16-1991. Epub 2016 Nov 4.


Precision targeted therapy of ovarian cancer.

Sapiezynski J, Taratula O, Rodriguez-Rodriguez L, Minko T.

J Control Release. 2016 Dec 10;243:250-268. doi: 10.1016/j.jconrel.2016.10.014. Epub 2016 Oct 14. Review.


CRM1/XPO1 is associated with clinical outcome in glioma and represents a therapeutic target by perturbing multiple core pathways.

Liu X, Chong Y, Tu Y, Liu N, Yue C, Qi Z, Liu H, Yao Y, Liu H, Gao S, Niu M, Yu R.

J Hematol Oncol. 2016 Oct 12;9(1):108.


Methylation-induced silencing of maspin contributes to the proliferation of human glioma cells.

Xu L, Liu H, Yu J, Wang Z, Zhu Q, Li Z, Zhong Q, Zhang S, Qu M, Lan Q.

Oncol Rep. 2016 Jul;36(1):57-64. doi: 10.3892/or.2016.4783. Epub 2016 May 4.


Differential localization of glioblastoma subtype: implications on glioblastoma pathogenesis.

Steed TC, Treiber JM, Patel K, Ramakrishnan V, Merk A, Smith AR, Carter BS, Dale AM, Chow LM, Chen CC.

Oncotarget. 2016 May 3;7(18):24899-907. doi: 10.18632/oncotarget.8551.


Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation but resistant to temozolomide.

Schmid RS, Simon JM, Vitucci M, McNeill RS, Bash RE, Werneke AM, Huey L, White KK, Ewend MG, Wu J, Miller CR.

Neuro Oncol. 2016 Jul;18(7):962-73. doi: 10.1093/neuonc/nov321. Epub 2016 Jan 28.


Impaired TGF-β induced growth inhibition contributes to the increased proliferation rate of neural stem cells harboring mutant p53.

Kumar P, Naumann U, Aigner L, Wischhusen J, Beier CP, Beier D.

Am J Cancer Res. 2015 Oct 15;5(11):3436-45. eCollection 2015.


Intrinsic Astrocyte Heterogeneity Influences Tumor Growth in Glioma Mouse Models.

Irvin DM, McNeill RS, Bash RE, Miller CR.

Brain Pathol. 2017 Jan;27(1):36-50. doi: 10.1111/bpa.12348. Epub 2016 Apr 13.


Generation of brain tumours in mice by Cre-mediated recombination of neural progenitors in situ with the tamoxifen metabolite endoxifen.

Benedykcinska A, Ferreira A, Lau J, Broni J, Richard-Loendt A, Henriquez NV, Brandner S.

Dis Model Mech. 2016 Feb;9(2):211-20. doi: 10.1242/dmm.022715. Epub 2015 Dec 24.


Pediatric gliomas as neurodevelopmental disorders.

Baker SJ, Ellison DW, Gutmann DH.

Glia. 2016 Jun;64(6):879-95. doi: 10.1002/glia.22945. Epub 2015 Dec 6. Review.


An AKT3-FOXG1-reelin network underlies defective migration in human focal malformations of cortical development.

Baek ST, Copeland B, Yun EJ, Kwon SK, Guemez-Gamboa A, Schaffer AE, Kim S, Kang HC, Song S, Mathern GW, Gleeson JG.

Nat Med. 2015 Dec;21(12):1445-54. doi: 10.1038/nm.3982. Epub 2015 Nov 2.


Rapid tumor induction in zebrafish by TALEN-mediated somatic inactivation of the retinoblastoma1 tumor suppressor rb1.

Solin SL, Shive HR, Woolard KD, Essner JJ, McGrail M.

Sci Rep. 2015 Sep 8;5:13745. doi: 10.1038/srep13745.


Expression Analysis of Genes Involved in the RB/E2F Pathway in Astrocytic Tumors.

Ferreira WA, Araújo MD, Anselmo NP, de Oliveira EH, Brito JR, Burbano RR, Harada ML, Borges Bdo N.

PLoS One. 2015 Aug 28;10(8):e0137259. doi: 10.1371/journal.pone.0137259. eCollection 2015.


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