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Items: 1 to 20 of 27


Activation of murine pre-proglucagon-producing neurons reduces food intake and body weight.

Gaykema RP, Newmyer BA, Ottolini M, Raje V, Warthen DM, Lambeth PS, Niccum M, Yao T, Huang Y, Schulman IG, Harris TE, Patel MK, Williams KW, Scott MM.

J Clin Invest. 2017 Mar 1;127(3):1031-1045. doi: 10.1172/JCI81335. Epub 2017 Feb 20.


Subchronical treatment with Fluoxetine modifies the activity of the MCHergic and hypocretinergic systems. Evidences from peptide CSF concentration and gene expression.

Calegare BF, Costa A, Fernandes L, Dias AL, Torterolo P, Almeida VD.

Sleep Sci. 2016 Apr-Jun;9(2):89-93. doi: 10.1016/j.slsci.2016.05.010. Epub 2016 Jun 7.


Comprehensive Behavioral Analysis of Male Ox1r (-/-) Mice Showed Implication of Orexin Receptor-1 in Mood, Anxiety, and Social Behavior.

Abbas MG, Shoji H, Soya S, Hondo M, Miyakawa T, Sakurai T.

Front Behav Neurosci. 2015 Dec 10;9:324. doi: 10.3389/fnbeh.2015.00324. eCollection 2015 Dec 10.


CDH13 and HCRTR2 May Be Associated with Hypersomnia Symptom of Bipolar Depression: A Genome-Wide Functional Enrichment Pathway Analysis.

Cho CH, Lee HJ, Woo HG, Choi JH, Greenwood TA, Kelsoe JR.

Psychiatry Investig. 2015 Jul;12(3):402-7. doi: 10.4306/pi.2015.12.3.402. Epub 2015 Jul 6.


Early life social stress induced changes in depression and anxiety associated neural pathways which are correlated with impaired maternal care.

Murgatroyd CA, Peña CJ, Podda G, Nestler EJ, Nephew BC.

Neuropeptides. 2015 Aug;52:103-11. doi: 10.1016/j.npep.2015.05.002. Epub 2015 May 28.


The role of orexin in post-stroke inflammation, cognitive decline, and depression.

Song J, Kim E, Kim CH, Song HT, Lee JE.

Mol Brain. 2015 Mar 11;8:16. doi: 10.1186/s13041-015-0106-1. Review.


To ingest or rest? Specialized roles of lateral hypothalamic area neurons in coordinating energy balance.

Brown JA, Woodworth HL, Leinninger GM.

Front Syst Neurosci. 2015 Feb 18;9:9. doi: 10.3389/fnsys.2015.00009. eCollection 2015 Feb 18. Review.


Hypocretin (orexin) neuromodulation of stress and reward pathways.

Giardino WJ, de Lecea L.

Curr Opin Neurobiol. 2014 Dec;29:103-8. doi: 10.1016/j.conb.2014.07.006. Epub 2014 Jul 20. Review.


K-Lysine acetyltransferase 2a regulates a hippocampal gene expression network linked to memory formation.

Stilling RM, Rönicke R, Benito E, Urbanke H, Capece V, Burkhardt S, Bahari-Javan S, Barth J, Sananbenesi F, Schütz AL, Dyczkowski J, Martinez-Hernandez A, Kerimoglu C, Dent SY, Bonn S, Reymann KG, Fischer A.

EMBO J. 2014 Sep 1;33(17):1912-27. doi: 10.15252/embj.201487870. Epub 2014 Jul 14.


The hypocretin/orexin system mediates the extinction of fear memories.

Flores Á, Valls-Comamala V, Costa G, Saravia R, Maldonado R, Berrendero F.

Neuropsychopharmacology. 2014 Nov;39(12):2732-41. doi: 10.1038/npp.2014.146. Epub 2014 Jun 16.


Attenuated orexinergic signaling underlies depression-like responses induced by daytime light deficiency.

Deats SP, Adidharma W, Lonstein JS, Yan L.

Neuroscience. 2014 Jul 11;272:252-60. doi: 10.1016/j.neuroscience.2014.04.069. Epub 2014 May 9.


Orexin regulates bone remodeling via a dominant positive central action and a subordinate negative peripheral action.

Wei W, Motoike T, Krzeszinski JY, Jin Z, Xie XJ, Dechow PC, Yanagisawa M, Wan Y.

Cell Metab. 2014 Jun 3;19(6):927-40. doi: 10.1016/j.cmet.2014.03.016. Epub 2014 May 1.


Orexin antagonists for neuropsychiatric disease: progress and potential pitfalls.

Yeoh JW, Campbell EJ, James MH, Graham BA, Dayas CV.

Front Neurosci. 2014 Feb 25;8:36. doi: 10.3389/fnins.2014.00036. eCollection 2014 Feb 25. Review.


Hypocretin (orexin) regulation of sleep-to-wake transitions.

de Lecea L, Huerta R.

Front Pharmacol. 2014 Feb 12;5:16. doi: 10.3389/fphar.2014.00016. eCollection 2014 Feb 12. Review.


Pharmacological rescue of Ras signaling, GluA1-dependent synaptic plasticity, and learning deficits in a fragile X model.

Lim CS, Hoang ET, Viar KE, Stornetta RL, Scott MM, Zhu JJ.

Genes Dev. 2014 Feb 1;28(3):273-89. doi: 10.1101/gad.232470.113.


Anxiolytic function of the orexin 2/hypocretin A receptor in the basolateral amygdala.

Arendt DH, Hassell J, Li H, Achua JK, Guarnieri DJ, Dileone RJ, Ronan PJ, Summers CH.

Psychoneuroendocrinology. 2014 Feb;40:17-26. doi: 10.1016/j.psyneuen.2013.10.010. Epub 2013 Oct 30.


LSN2424100: a novel, potent orexin-2 receptor antagonist with selectivity over orexin-1 receptors and activity in an animal model predictive of antidepressant-like efficacy.

Fitch TE, Benvenga MJ, Jesudason CD, Zink C, Vandergriff AB, Menezes MM, Schober DA, Rorick-Kehn LM.

Front Neurosci. 2014 Jan 28;8:5. doi: 10.3389/fnins.2014.00005. eCollection 2014 Jan 28.


Evaluation of heritable determinants of blood and brain serotonin homeostasis using recombinant inbred mice.

Ye R, Carneiro AM, Airey D, Sanders-Bush E, Williams RW, Lu L, Wang J, Zhang B, Blakely RD.

Genes Brain Behav. 2014 Mar;13(3):247-60. doi: 10.1111/gbb.12092. Epub 2013 Oct 31.


Reward-based behaviors and emotional processing in human with narcolepsy-cataplexy.

Bayard S, Dauvilliers YA.

Front Behav Neurosci. 2013 May 23;7:50. doi: 10.3389/fnbeh.2013.00050. eCollection 2013 May 23.


Hypersomnia and depressive symptoms: methodological and clinical aspects.

Dauvilliers Y, Lopez R, Ohayon M, Bayard S.

BMC Med. 2013 Mar 21;11:78. doi: 10.1186/1741-7015-11-78. Review.

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